A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain (PARA_OA_012)

Paradigm Biopharmaceuticals · ClinicalTrials.gov registration

Anecdotalcounts toward this tier

The pivotal phase 3 readout to watch: interim DSMB review targeted late 2026, primary top-line results expected first quarter of 2027.

Population: Adults with knee OA pain; pivotal phase 3, ~65 sites, enrolment completed 2026
Intervention: Subcutaneous injectable PPS (Zilosul)
Comparator: Placebo
Limitations: No results yet; registration record included for tracking.

Cited by

2 entries reference this study

Pentosan polysulfate (PPS)
Peptides → Clinically studied · key study
PROM.Promising
Peptide "cycles" for joint repair
Peptides → Preclinical & experimental
ANECD.Anecdotal