Evidence Map

The Evidence Map

The whole guide on one plate. Every intervention, placed by how strong its science is — click any name to open its entry.

	Strongmultiple RCTs	Promisingearly human trials	Preclinicalanimal / in-vitro	Anecdotalcommunity reports	Not supportedtrials show no meaningful benefit
Foods		gelatin + vit C	dietary collagen omega-3s	bone broth chicken feet
Supplements	collagen (FORTIGEL)	boswellia creatine curcumin eggshell membrane glucosamine MSM oral HA UC-II vitamin D vitamin K2	NMN TMG
Peptides		pentosan polysulfate	BPC-157 GHK-Cu TB-500	Cartalax Sigumir
Injections		adipose MSC stem cells (BMAC)cultured MSC high-dose PRP			hyaluronic acid
Surgery	MACI microfracture OATS osteotomy	Agili-C ICC / CEMTRO Cell allograft

Strong

multiple RCTs

collagen (FORTIGEL) SUPP MACI SURG microfracture SURG OATS SURG osteotomy SURG

Promising

early human trials

gelatin + vit C FOOD adipose MSC INJ stem cells (BMAC) INJ cultured MSC INJ high-dose PRP INJ pentosan polysulfate PEP boswellia SUPP creatine SUPP curcumin SUPP eggshell membrane SUPP glucosamine SUPP MSM SUPP oral HA SUPP UC-II SUPP vitamin D SUPP vitamin K2 SUPP Agili-C SURG ICC / CEMTRO Cell SURG allograft SURG

Preclinical

animal / in-vitro

dietary collagen FOOD omega-3s FOOD BPC-157 PEP GHK-Cu PEP TB-500 PEP NMN SUPP TMG SUPP

Anecdotal

community reports

bone broth FOOD chicken feet FOOD Cartalax PEP Sigumir PEP

Not supported

trials show no meaningful benefit

hyaluronic acid INJ

Placement reflects the best available human evidence for cartilage specifically, not general popularity. FOOD · SUPP · PEP · INJ · SURG mark the domain. Full reasoning inside each entry.