Study Library

1079 papers

Every paper cited anywhere on this site, in one browsable place — what was studied, in whom, and what it actually found. Open one for the full record and the entries that cite it.

1079 of 1079

Review · 2026
Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157 — A Review
Matek D et al. · Pharmaceuticals · cited by Peptides
In vitro · 2026 · n=12
Endothelium-Dependent Nitric Oxide-Mediated Vasorelaxant Effects of BPC 157 in Human Internal Mammary Artery
Yildirim AK et al. · Journal of Clinical Medicine · cited by Peptides
Review · 2026
BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers
Mateescu DM et al. · Pharmaceutics · cited by Peptides
Registry · 2026 · n=120
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of Pentadecapeptide BPC 157 for Accelerated Repair of Acute Grade II Hamstring Strain Confirmed by MRI
Hudson Biotech · ClinicalTrials.gov registration · cited by Peptides
Review · 2026
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications
Villegas Meza AD et al. · JBJS Reviews · cited by Peptides
RCT · 2026 · n=30
Oral Administration of Specific Bioactive Collagen Peptides in the Treatment of Moderate Forms of Atopic Dermatitis: A New Approach
Proksch E et al. · Skin Pharmacology and Physiology · cited by Supplements
Meta-analysis · 2026
The Effect of Vitamin C Supplements on Urinary Stone Risk: A Systematic Review and Meta-Analysis
Farkouh A et al. · Journal of Endourology · cited by Supplements
RCT · 2026 · n=120
Effect of aerobic exercise of different intensity on articular cartilage metabolism in patients with knee osteoarthritis: A randomized controlled trial
Song L et al. · Medicine · cited by Exercise & Rehab
Cohort · 2026 · n=3,056
Knee muscle strength as a mediator of sex differences in incident knee osteoarthritis
Li X et al. · Arthritis Research & Therapy · cited by Exercise & Rehab
Cohort · 2026 · n=620
Dietary factors and MRI-Defined synovial inflammation progression in knee osteoarthritis: a longitudinal mixed-effects analysis from the osteoarthritis initiative
Wang Y et al. · Frontiers in Aging · cited by Foods & Nutrition
Cohort · 2026 · n=615
Ultra-processed Foods and Muscle Fat Infiltration at Thigh MRI: Data from the Osteoarthritis Initiative
Akkaya Z et al. · Radiology · cited by Foods & Nutrition
Meta-analysis · 2026 · n=392
Tart cherry intake and serum uric acid: Meta-analysis of randomized controlled trials and evidence from network pharmacology
Zhang Z et al. · Asia Pacific Journal of Clinical Nutrition · cited by Foods & Nutrition
Systematic review · 2026
Pomegranate (Punica granatum) as an adjunctive therapy in rheumatic diseases: A systematic review
de Carvalho JF et al. · Clinical Nutrition ESPEN · cited by Foods & Nutrition
Review · 2026
Crosstalk Between Inflammation and Cellular Senescence in Osteoarthritis: Modulatory Actions of Olive Oil and Its Bioactive Compounds
Medoro A et al. · Mediators of Inflammation · cited by Foods & Nutrition
RCT · 2026 · n=34
Recombinant human growth hormone (rHGH) for muscle enhancement in knee osteoarthritis: protocol for a pilot, randomised placebo-controlled trial
Shah A et al. · BMJ Open · cited by Peptides
Review · 2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Dominikowski A et al. · Frontiers in Endocrinology · cited by Peptides
Animal · 2026
Glycyl-L-histidyl-L-lysine-Cu2(+) (GHK-Cu) Attenuates CuSO(4) or LPS induced-inflammation in Zebrafish larvae model
Hu J et al. · European Journal of Pharmacology · cited by Peptides
Animal · 2026
The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways
Wen H et al. · Biogerontology · cited by Peptides
Review · 2026
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
Mendias CL et al. · Sports Medicine · cited by Peptides
Review · 2026
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians
Mayfield CK et al. · The American Journal of Sports Medicine · cited by Peptides
Review · 2026
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
Rahman OF et al. · JAAOS Global Research and Reviews · cited by Peptides
Meta-analysis · 2026 · n=1,172
The time-effect relationship of intra-articular ozone injection for knee osteoarthritis: a systematic review and meta-analysis
Chen F et al. · Frontiers in Pain Research · cited by Injections
Meta-analysis · 2026 · n=409
Ozone injections reduce pain in knee osteoarthritis: a systematic review and meta-analysis
Arias-Vázquez PI et al. · Medical Gas Research · cited by Injections
Meta-analysis · 2026 · n=1,376
Comparative efficacy of platelet-rich plasma monotherapy versus combination therapies for knee osteoarthritis: a systematic review and network meta-analysis
Luan D et al. · Journal of Orthopaedic Surgery and Research · cited by Injections
RCT · 2026 · n=65
The differential impact of three different NAD(+) boosters on circulatory NAD and microbial metabolism in humans
Christen S et al. · Nature Metabolism · cited by Supplements
Meta-analysis · 2026 · n=349
Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Zhang M et al. · Nutrients · cited by Supplements
Meta-analysis · 2026
Safety and Metabolism-Related Outcomes of Oral Nicotinamide Mononucleotide Supplementation in Adults: A Systematic Review and Meta-Analysis
Yang W et al. · Nutrients · cited by Supplements
Systematic review · 2026
Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials
Sun JN et al. · Nutrition Journal · cited by Supplements
Animal · 2026
Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study
Biçer O et al. · Joint Diseases and Related Surgery · cited by Peptides
RCT · 2026 · n=61
Effects of pentosan polysulfate sodium on synovial fluid biomarkers in moderate to severe knee osteoarthritis: an exploratory, phase 2, randomized, double-blind, placebo-controlled trial
Skerrett DL et al. · Arthritis Research & Therapy · cited by Peptides
Animal · 2026
Effects of pentosan polysulfate sodium on joint structure and function out to six months in naturally-occurring canine osteoarthritis
Stapledon CJM et al. · PLoS One · cited by Peptides
Case series · 2026 · n=3
Pentosan Polysulfate Maculopathy Following Subcutaneous Injections for Arthritis
Fung AT et al. · JAMA Ophthalmology · cited by Peptides
In vitro · 2026
Pentosan Polysulfate and Heparin Exhibit Comparable Interactions with Platelet Factor 4, Suggesting a Potential Risk of Thrombocytopenia
Nizzolo S et al. · ACS Omega · cited by Peptides
Review · 2026
Elamipretide: The first cardiolipin-directed mitochondrial therapeutic for Barth syndrome approved under accelerated approval
Zhao C et al. · Drug Discoveries & Therapeutics · cited by Peptides
Cohort · 2026 · n=187
Risk factors for pentosan polysulfate maculopathy
Shiromani S et al. · Canadian Journal of Ophthalmology · cited by Peptides
Cohort · 2026 · n=336
Pigmentary Maculopathy in Patients with Interstitial Cystitis: Association with Pentosan Polysulfate and Other Therapies
Qin S et al. · Ophthalmology Science · cited by Peptides
Review · 2026 · n=59
Photobiomodulation for the treatment of knee osteoarthritis: therapeutic effects and molecular mechanism
Xia P et al. · Frontiers in Cell and Developmental Biology · cited by Light, Heat & Devices and Exercise & Rehab
Review · 2026
Extracorporeal Shock Wave Therapy in Knee Osteoarthritis: A Mechanistic Narrative Review of Neurogenic Inflammation and the MMP/ADAMTS Axis
Guo Z et al. · International Journal of General Medicine · cited by Light, Heat & Devices
RCT · 2026 · n=84
Effect of an oral complementary medicine combination for symptomatic knee osteoarthritis: A double-blind, randomized, placebo-controlled trial
Yuan S et al. · Osteoarthritis and Cartilage · cited by Supplements
Review · 2026
Rarely reported cases of hepatotoxicity associated with turmeric- and curcuminoid-containing dietary supplements: a comprehensive review by USP
Akhtar N et al. · Pharmaceutical Biology · cited by Supplements
RCT · 2026 · n=68
The effect of curcumin and piperine co-supplementation on glycemic indices in prediabetes: A triple-blind randomized controlled trial
Ghazaee H et al. · Avicenna Journal of Phytomedicine · cited by Supplements
Animal · 2026
Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration
Yu J et al. · Aging Cell · cited by Supplements
Animal · 2026
NMN-primed exosomes derived from infrapatellar fat pad mesenchymal stem cells exert synergistic anti-inflammatory and cartilage-protective effects via MERTK pathway activation in knee osteoarthritis
Chen KT et al. · International Journal of Pharmaceutics · cited by Supplements
RCT · 2026 · n=70
Pilot trials of oral betaine in participants with metabolic dysfunction-associated steatotic liver disease and elevated alanine aminotransferase
Lim AS et al. · Hepatology · cited by Supplements
Animal · 2026 · n=24
Betaine Downregulates RARRES1 to Alleviate Cartilage Fibrosis and Promote Hyaline Cartilage Repair
Wang S et al. · International Journal of Molecular Sciences · cited by Supplements
RCT · 2026 · n=180
Two Years of Menaquinone-7 Supplementation and Coronary Artery Calcification: A Randomized Clinical Trial
Vossen LM et al. · JAMA Cardiology · cited by Supplements
RCT · 2026 · n=251
Five-Year Follow-up of a Multicenter Randomized Controlled Trial Comparing an Aragonite-Based Scaffold With Microfracture and Debridement for Chondral and Osteochondral Knee Lesions
Altschuler N et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
Systematic review · 2026
Peptide Supplements and Their Therapeutic Applications in Sports Medicine
Tewari K et al. · The American Journal of Sports Medicine · cited by Peptides
Review · 2025
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
Araj SK et al. · International Journal of Molecular Sciences · cited by Peptides
In vitro · 2025
Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity
Al-Dulaimi S et al. · Biogerontology · cited by Peptides
In vitro · 2025
The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy
Gatta M et al. · Stem Cell Rev Rep · cited by Peptides
Animal · 2025
Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats
Matek D et al. · Pharmaceutics · cited by Peptides
Registry · 2025 · n=40
A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery
Parlay Wellness · ClinicalTrials.gov registration · cited by Peptides
Systematic review · 2025
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
Vasireddi N et al. · HSS Journal · cited by Peptides
Review · 2025
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
McGuire FP et al. · Current Reviews in Musculoskeletal Medicine · cited by Peptides
Review · 2025
Multifunctionality and Possible Medical Application of the BPC 157 Peptide — Literature and Patent Review
Józwiak M et al. · Pharmaceuticals · cited by Peptides
Review · 2025
BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide's Cytotoxic and Damaging Actions, but Maintaining, Promoting, or Recovering Their Essential Protective Functions. Comment on Józwiak et al
Sikiric P et al. · Pharmaceuticals · cited by Peptides
RCT · 2025 · n=68
Efficacy of combined undenatured type II collagen and hydrolysed collagen supplementation in knee osteoarthritis: a randomised controlled trial
Yuenyongviwat V et al. · Scientific Reports · cited by Supplements
Systematic review · 2025
The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review
Brueckheimer PJ et al. · Orthopedic Reviews · cited by Supplements
RCT · 2025 · n=80
Efficacy and safety of low-molecular-weight collagen peptides in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial
Park SY et al. · Frontiers in Nutrition · cited by Supplements
RCT · 2025 · n=77
The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Wang Y et al. · Journal of Cosmetic Dermatology · cited by Supplements
RCT · 2025 · n=50
Collagen Peptide Supplementation Enhances Muscle-Tendon Stiffness and Explosive Strength: A 16-wk Randomized Controlled Trial
Miyamoto N et al. · Medicine and Science in Sports and Exercise · cited by Supplements
RCT · 2025 · n=20
Hydrolysed Collagen Supplementation Enhances Patellar Tendon Adaptations to 12 Weeks' Resistance Training in Middle-Aged Men
Nulty CD et al. · European Journal of Sport Science · cited by Supplements
RCT · 2025 · n=11
High-intensity resistance training and collagen supplementation improve patellar tendon adaptations in professional female soccer athletes
Lee J et al. · Experimental Physiology · cited by Supplements
Meta-analysis · 2025 · n=15,684
Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis
Yan L et al. · BMJ · cited by Exercise & Rehab
Meta-analysis · 2025 · n=3,463
Optimal resistance training strategies for knee osteoarthritis symptom relief: a systematic review and network meta-analysis
Yang Y et al. · BMC Musculoskeletal Disorders · cited by Exercise & Rehab
Cohort · 2025 · n=4,403
Ultra-processed food consumption is associated with knee osteoarthritis: Data from the Osteoarthritis Initiative
Akkaya Z et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
Review · 2025
Ultra-Processed Food and Its Impact on Bone Health and Joint Diseases: A Scoping Review
Ciaffi J et al. · Nutrients · cited by Foods & Nutrition
Meta-analysis · 2025 · n=2,800
Comparison of weight loss interventions in overweight and obese adults with knee osteoarthritis: A systematic review and network meta-analysis of randomized trials
Shahid A et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
Animal · 2025 · n=40
Anti-Inflammatory and Joint-Protective Effects of Blueberries in a Monosodium Iodoacetate (MIA)-Induced Rat Model of Osteoarthritis
South SM et al. · Nutrients · cited by Foods & Nutrition
In vitro · 2025
Sustainable gelatin extraction from poultry skin-head-feet blend: An ultrasound-assisted approach
Bhargavi PK et al. · Poultry Science · cited by Foods & Nutrition
In vitro · 2025
Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects
Greco V et al. · Bioconjugate Chemistry · cited by Peptides
Animal · 2025
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms
Mao S et al. · Frontiers in Pharmacology · cited by Peptides
Review · 2025
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective
Mortazavi SM et al. · BioImpacts · cited by Peptides
Systematic review · 2025 · n=1,652
A Greater Platelet Dose May Yield Better Clinical Outcomes for Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Systematic Review
Berrigan WA et al. · Arthroscopy · cited by Injections
Meta-analysis · 2025 · n=1,616
Efficacy of intra-articular platelet-rich plasma compared with placebo in knee osteoarthritis: A systematic review and meta-analysis
Auroux M et al. · Joint Bone Spine · cited by Injections
RCT · 2025 · n=75
Microfragmented Adipose Tissue Injection Reduced Pain Compared With a Saline Control Among Patients With Symptomatic Osteoarthritis of the Knee During 1-Year Follow-Up: A Randomized Controlled Trial
Richter DL et al. · Arthroscopy · cited by Injections
Meta-analysis · 2025
Microfragmented Adipose Tissue as an Alternative to Platelet-Rich Plasma for Intra-articular Injection in Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Park YB et al. · The American Journal of Sports Medicine · cited by Injections
Systematic review · 2025 · n=5
The effects of oxygen-ozone therapy in knee osteoarthritis: A systematic review
Farì G et al. · Journal of Back and Musculoskeletal Rehabilitation · cited by Injections
Animal · 2025 · n=33
Resveratrol does not mimic the positive effects of calorie restriction on lifespan in Microcebus murinus
Pifferi F et al. · Communications Biology · cited by Supplements
Review · 2025
Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects
Ren ZQ et al. · MedComm · cited by Supplements
Review · 2025
The Influence of Sirtuin 6 on Chondrocyte Senescence in Osteoarthritis Under Aging: Focusing on Mitochondrial Dysfunction and Oxidative Stress
Zhao H et al. · Antioxidants · cited by Supplements
Meta-analysis · 2025
The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis
Prokopidis K et al. · Journal of Cachexia, Sarcopenia and Muscle · cited by Supplements
Animal · 2025
NAD+ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice
Wang YJ et al. · Atherosclerosis · cited by Supplements
RCT · 2025 · n=100
Effect of Different Neuromuscular Electrical Stimulation Modalities on Clinical and Functional Outcomes in Older Adults with Knee Osteoarthritis: A Randomized Controlled Trial
De Almeida CC et al. · Clinical Interventions in Aging · cited by Light, Heat & Devices
Cohort · 2025
Limited effects of non-steroidal anti-inflammatory drugs (NSAIDs) on imaging outcomes in osteoarthritis: observational data from the osteoarthritis initiative (OAI)
Kreutzinger V et al. · BMC Musculoskeletal Disorders · cited by Precautions
Case series · 2025 · n=2
Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study
Lee E et al. · Alternative Therapies in Health and Medicine · cited by Peptides
Registry · 2025
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain (PARA_OA_012)
Paradigm Biopharmaceuticals · ClinicalTrials.gov registration · cited by Peptides
Review · 2025
A review of the clinical efficacy and adverse effects of disease modifying osteoarthritic drugs (DMOADs) in dogs with special focus on glucosamine and pentosan polysulfate; do they work?
Bwalya EC et al. · The Journal of Veterinary Medical Science · cited by Peptides
Cohort · 2025 · n=14,053
Retrospective study of incidence/prevalence of pigmentary maculopathy and retinopathy in patients receiving pentosan polysulfate sodium
Yuan Z et al. · PLoS One · cited by Peptides
RCT · 2025 · n=176
ReCLAIM-2: A Randomized Phase II Clinical Trial Evaluating Elamipretide in Age-related Macular Degeneration, Geographic Atrophy Growth, Visual Function, and Ellipsoid Zone Preservation
Ehlers JP et al. · Ophthalmology Science · cited by Peptides
Cohort · 2025 · n=133
An Observational Follow-up Study to Investigate the Duration of Treatment Effect With Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain (PARA_OA_006)
Paradigm Biopharmaceuticals Ltd · ClinicalTrials.gov · cited by Peptides
Review · 2025
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality
Hall BP et al. · Progress in Retinal and Eye Research · cited by Peptides
Registry · 2025 · n=11,471
Post-marketing safety of pentosan polysulfate sodium: a 21-year pharmacovigilance analysis of the FAERS database
Wang B et al. · Frontiers in Medicine · cited by Peptides
In vitro · 2025
Near-infrared photobiomodulation stimulates viability and cartilage matrix synthesis in human chondrocytes
Oliveira S et al. · Scientific Reports · cited by Light, Heat & Devices
Animal · 2025
Optimizing LED photobiomodulation parameters to prevent cartilage matrix degradation in knee osteoarthritis: in vitro and in vivo study
Fan T et al. · Journal of Orthopaedic Surgery and Research · cited by Light, Heat & Devices
Review · 2025
Photobiomodulation in Promoting Cartilage Regeneration
Hang NLT et al. · International Journal of Molecular Sciences · cited by Light, Heat & Devices
Review · 2025
Effects of Photobiomodulation on Osteoarthritis from In Vivo and In Vitro Studies: A Narrative Review
Kunimatsu R et al. · International Journal of Molecular Sciences · cited by Light, Heat & Devices
Meta-analysis · 2025 · n=2,078
Physical modalities for the treatment of knee osteoarthritis: a network meta-analysis
Lan X et al. · Aging Clinical and Experimental Research · cited by Light, Heat & Devices
Meta-analysis · 2025 · n=913
Effect of turmeric products on knee osteoarthritis: a systematic review and network meta-analysis
Wai HS et al. · BMC Complementary Medicine and Therapies · cited by Supplements
Meta-analysis · 2025 · n=4,599
Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis
Zhang Y et al. · Nutrients · cited by Supplements
RCT · 2025 · n=9
A pharmacokinetic study and critical reappraisal of curcumin formulations enhancing bioavailability
Kroon MAGM et al. · iScience · cited by Supplements
Case report · 2025 · n=1
Drug-Induced Liver Injury Secondary to Turmeric Supplement Containing Piperine: A Case Report
Koo N et al. · Cureus · cited by Supplements
Meta-analysis · 2025 · n=1,705
Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Hsueh HC et al. · BMC Complementary Medicine and Therapies · cited by Supplements
Meta-analysis · 2025
Effects of Curcuminoids Plus Piperine Co-Supplementation on Liver Enzymes and Inflammation in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis
Karimi M et al. · Food Science & Nutrition · cited by Supplements
RCT · 2025 · n=137
Resveratrol supplementation improves functional performance in knee osteoarthritis by upregulating sirtuin 1: a randomized study
Karim A et al. · Inflammopharmacology · cited by Supplements
Animal · 2025 · n=40
Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81
Wang M et al. · Stem Cell Research & Therapy · cited by Supplements
Animal · 2025
Altered nicotinamide adenine dinucleotide metabolism drives cartilage degeneration and osteoarthritis
Wu X et al. · Clinical and Translational Medicine · cited by Supplements
RCT · 2025 · n=40
Additional Benefits of Creatine Supplementation with Physical Therapy and Resistance Exercise in Knee Osteoarthritis: A Randomized Controlled Trial
Osama M et al. · Journal of Clinical Medicine · cited by Supplements
Animal · 2025 · n=40
Screen of FDA-approved drug library identifies vitamin K as anti-ferroptotic drug for osteoarthritis therapy through Gas6
Shi Y et al. · Journal of Pharmaceutical Analysis · cited by Supplements
Animal · 2025
Vitamins D and K jointly protect against osteoarthritis via regulating OSCAR during osteoclastogenesis
Zhao Y et al. · Journal of Orthopaedic Translation · cited by Supplements
Case series · 2025 · n=48
Intermediate-Term Clinical Outcomes of High-Density Autologous Chondrocyte Implantation in Patients with Concomitant Anterior Cruciate Ligament Reconstruction and Focal Chondral Lesions
Guillén-Vicente I et al. · Cartilage · cited by Treatments & Surgery
Meta-analysis · 2025 · n=5,162
Conversion to Total Knee Arthroplasty After High Tibial Osteotomy: A Systematic Review and Meta-analysis
Loke RWK et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
RCT · 2025 · n=96
Recombinant human thymosin beta 4 improves ischemic cardiac dysfunction in mice and patients with acute ST-segment elevation myocardial infarction after reperfusion
Zhang Y et al. · Cardiovascular Research · cited by Peptides
Systematic review · 2025 · n=494
Medical and surgical interventions for neurotrophic keratopathy
Kruoch Z et al. · Cochrane Database of Systematic Reviews · cited by Peptides
Review · 2024
Aging and the emerging role of cellular senescence in osteoarthritis
Diekman BO et al. · Osteoarthritis Cartilage · cited by Peptides
Review · 2024
Therapeutic targets and potential delivery systems of melatonin in osteoarthritis
Xiong Z et al. · Front Immunol · cited by Peptides
Case series · 2024 · n=12
Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study
Lee E et al. · Alternative Therapies in Health and Medicine · cited by Peptides
Meta-analysis · 2024 · n=3,165
Efficacy and safety of collagen derivatives for osteoarthritis: A trial sequential meta-analysis
Liang CW et al. · Osteoarthritis and Cartilage · cited by Supplements
RCT · 2024 · n=100
Management and Amelioration of Knee Joint Osteoarthritis in Adults Using a Novel High-Functional Bovine Collagen Peptide as a Nutritional Therapy
Devasia S et al. · Cartilage · cited by Supplements
Meta-analysis · 2024
Impact of Collagen Peptide Supplementation in Combination with Long-Term Physical Training on Strength, Musculotendinous Remodeling, Functional Recovery, and Body Composition in Healthy Adults: A Systematic Review with Meta-analysis
Bischof K et al. · Sports Medicine · cited by Supplements
RCT · 2024 · n=85
Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial
Vleminckx S et al. · Journal of Cosmetic Dermatology · cited by Supplements
RCT · 2024 · n=182
Impact of Specific Bioactive Collagen Peptides on Joint Discomforts in the Lower Extremity during Daily Activities: A Randomized Controlled Trial
Schulze C et al. · International Journal of Environmental Research and Public Health · cited by Supplements
Animal · 2024 · n=31
The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients-A translational large animal model for a nutritional therapy option
Dobenecker B et al. · PLoS One · cited by Supplements
RCT · 2024 · n=25
Collagen Peptide Supplementation during Training Does Not Further Increase Connective Tissue Protein Synthesis Rates
Kirmse M et al. · Medicine and Science in Sports and Exercise · cited by Supplements
RCT · 2024 · n=6
Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals
Virgilio N et al. · Frontiers in Nutrition · cited by Supplements
Cohort · 2024 · n=57
Two Members of Vitamin-K-Dependent Proteins, Gla-Rich Protein (GRP) and Matrix Gla Protein (MGP), as Possible New Players in the Molecular Mechanism of Osteoarthritis
Kurtuluş B et al. · Journal of Clinical Medicine · cited by Foods & Nutrition
Case series · 2024 · n=14
The effect of a low-carbohydrate diet on evoked pain and quality of life in Non-Hispanic black women with knee osteoarthritis: a pilot study
Wiggins AM et al. · BMC Musculoskeletal Disorders · cited by Foods & Nutrition
Cohort · 2024 · n=163,987
Ultra-processed food consumption, genetic susceptibility, and the risk of hip/knee osteoarthritis
Wei Y et al. · Clinical Nutrition · cited by Foods & Nutrition
RCT · 2024 · n=54
Effect of prebiotic fiber on physical function and gut microbiota in adults, mostly women, with knee osteoarthritis and obesity: a randomized controlled trial
Fortuna R et al. · European Journal of Nutrition · cited by Foods & Nutrition
Cohort · 2024 · n=200
Diet influences knee osteoarthritis osteophyte formation via gut microbiota and serum metabolites
Zhu D et al. · iScience · cited by Foods & Nutrition
Animal · 2024 · n=63
Development of shoulder osteoarthritis and bone lesions in female and male rats subjected to a high fat/sucrose diet
Abughazaleh N et al. · Scientific Reports · cited by Foods & Nutrition
Cohort · 2024
Coffee and the risk of osteoarthritis: a two-sample, two-step multivariable Mendelian randomization study
Zhang W et al. · Frontiers in Genetics · cited by Foods & Nutrition
Cohort · 2024 · n=14,580
Effect of caffeine intake on self-reported and genetic prediction of osteoarthritis: an epidemiological study and Mendelian randomization analysis
Ji Z et al. · Frontiers in Nutrition · cited by Foods & Nutrition
RCT · 2024 · n=407
Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis
Bliddal H et al. · The New England Journal of Medicine · cited by Foods & Nutrition
Review · 2024
Dietary anthocyanins balance immune signs in osteoarthritis and obesity - update of human in vitro studies and clinical trials
Pomilio AB et al. · Critical Reviews in Food Science and Nutrition · cited by Foods & Nutrition
RCT · 2024 · n=66
Effects of Pomegranate (Punica granatum L.) Peel Extract Supplementation on Markers of Inflammation and Serum Matrix Metalloproteinase 1 in Women With Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Study
Rafraf M et al. · Nutrition and Metabolism Insights · cited by Foods & Nutrition
Cohort · 2024 · n=403,124
Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysis
Lv X et al. · PLoS One · cited by Foods & Nutrition
In vitro · 2024
Targeting PAR2-mediated inflammation in osteoarthritis: a comprehensive in vitro evaluation of oleocanthal's potential as a functional food intervention for chondrocyte protection and anti-inflammatory effects
Patnaik R et al. · BMC Musculoskeletal Disorders · cited by Foods & Nutrition
Animal · 2024 · n=32
Intra-articular administration of extra-virgin olive oil in degenerative osteoarthritis
Pamiry A et al. · Journal of Orthopaedic Surgery and Research · cited by Foods & Nutrition
Animal · 2024
Hyaluronan and chondroitin sulfate in chicken-vegetable bone broth delay osteoporosis progression
Seki Y et al. · Journal of Food Science · cited by Foods & Nutrition and Supplements
RCT · 2024 · n=262
Krill Oil for Knee Osteoarthritis: A Randomized Clinical Trial
Laslett LL et al. · JAMA · cited by Foods & Nutrition
In vitro · 2024
Migration of Nutrient Substances and Characteristic Changes of Chicken White Soup Emulsion from Chicken Skeleton during Cooking
Guan H et al. · Foods · cited by Foods & Nutrition
In vitro · 2024
Extraction and physicochemical characterization of native and broiler chicken feet gelatin
Usman M et al. · Journal of the Science of Food and Agriculture · cited by Foods & Nutrition
Review · 2024
Approach to the patient with controlled acromegaly and acromegalic arthropathy: clinical diagnosis and management
Pelsma ICM et al. · Pituitary · cited by Peptides
Animal · 2024
The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6
Bian Y et al. · Redox Biology · cited by Peptides
Meta-analysis · 2024
The Effect of Platelet Dose on Outcomes after Platelet Rich Plasma Injections for Musculoskeletal Conditions: A Systematic Review and Meta-Analysis
Berrigan W et al. · Current Reviews in Musculoskeletal Medicine · cited by Injections
Meta-analysis · 2024 · n=424
Intra-articular injections of ozone versus hyaluronic acid for knee osteoarthritis: a level I meta-analysis
Migliorini F et al. · European Journal of Orthopaedic Surgery and Traumatology · cited by Injections
RCT · 2024 · n=60
Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study
Morifuji M et al. · GeroScience · cited by Supplements
Meta-analysis · 2024 · n=342
Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials
Chen F et al. · Current Diabetes Reports · cited by Supplements
RCT · 2024 · n=20
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment
Orr ME et al. · GeroScience · cited by Supplements
RCT · 2024 · n=90
Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial
McDermott MM et al. · Nature Communications · cited by Supplements
RCT · 2024 · n=40
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial
Norheim KL et al. · Nature Aging · cited by Supplements
Review · 2024
SIRT1, resveratrol and aging
Rogina B et al. · Frontiers in Genetics · cited by Supplements
Systematic review · 2024
Addressing meniscal deficiency part 1: An umbrella review of systematic reviews and meta-analyses on meniscal allograft transplantation
Wu KA et al. · Journal of Experimental Orthopaedics · cited by Treatments & Surgery
RCT · 2024 · n=75
A controlled randomized trial with a 12-week follow-up investigating the effects of medium-frequency neuromuscular electrical stimulation on pain, VMO thickness, and functionality in patients with knee osteoarthritis
Moezy A et al. · BMC Musculoskeletal Disorders · cited by Light, Heat & Devices
Cohort · 2024 · n=133,762
Screening practices and risk assessment for maculopathy in pentosan polysulfate users across different exposure levels
Kwon HY et al. · Scientific Reports · cited by Peptides
Cohort · 2024 · n=10
Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER
Thompson WR et al. · Genetics in Medicine · cited by Peptides
RCT · 2024 · n=92
Efficacy and safety of pentosan polysulfate sodium in people with symptomatic knee osteoarthritis and dyslipidaemia: protocol of the MaRVeL trial
Siddiq MAB et al. · BMJ Open · cited by Peptides
Meta-analysis · 2024 · n=2,831
Adjunctive electrophysical therapies used in addition to land-based exercise therapy for osteoarthritis of the hip or knee: A systematic review and meta-analysis
French HP et al. · Osteoarthritis and Cartilage Open · cited by Light, Heat & Devices
Cohort · 2024 · n=4,197
Association of long-term use of non-steroidal anti-inflammatory drugs with knee osteoarthritis: a prospective multi-cohort study over 4-to-5 years
Salis Z et al. · Scientific Reports · cited by Precautions
Meta-analysis · 2024
The efficacy of extracorporeal shock wave therapy for knee osteoarthritis : an umbrella review
Tang P et al. · International Journal of Surgery (London, England) · cited by Light, Heat & Devices
Meta-analysis · 2024 · n=2,175
Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis
Zhao J et al. · Journal of Ethnopharmacology · cited by Supplements
Systematic review · 2024
The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses
Bideshki MV et al. · Phytotherapy Research · cited by Supplements
RCT · 2024 · n=16
Comparative Pharmacokinetics of Curcuminoids from Water-Dispersible Turmeric Extract Against a Curcuminoids-Piperine Combination: An Open-Label, Randomized, Balanced, 2-Treatment, 2-Sequence, 2-Period Crossover Study
Thanawala S et al. · Alternative Therapies in Health and Medicine · cited by Supplements
Cohort · 2024 · n=9,685
Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults
Likhitsup A et al. · JAMA Network Open · cited by Supplements
Animal · 2024 · n=32
The effect of MSM in the treatment of ankle arthrosis: Is MSM as effective as methylprednisolone or hyaluronic acid?
Akpınar K et al. · Journal of Orthopaedic Research · cited by Supplements
RCT · 2024 · n=142
Oral resveratrol in adults with knee osteoarthritis: A randomized placebo-controlled trial (ARTHROL)
Nguyen C et al. · PLoS Medicine · cited by Supplements
Meta-analysis · 2024
Effects of resveratrol on biochemical and structural outcomes in osteoarthritis: A systematic review and meta-analysis of preclinical studies
Zhao W et al. · Heliyon · cited by Supplements
Meta-analysis · 2024
Serum trace elements and osteoarthritis: A meta-analysis and Mendelian randomization study
Shi H et al. · Journal of Trace Elements in Medicine and Biology · cited by Supplements
Meta-analysis · 2024 · n=317
Effects of chronic betaine supplementation on exercise performance: Systematic review and meta-analysis
Zawieja E et al. · Journal of Sports Sciences · cited by Supplements
Animal · 2024
Vitamin K2 ameliorates osteoarthritis by suppressing ferroptosis and extracellular matrix degradation through activation GPX4's dual functions
He Q et al. · Biomedicine & Pharmacotherapy · cited by Supplements
Systematic review · 2024 · n=495
Autologous Osteochondral Transfer of the Knee Demonstrates Continued High Rates of Return to Sport and Low Rates of Conversion to Arthroplasty at Long-Term Follow-Up: A Systematic Review
Oeding JF et al. · Arthroscopy · cited by Treatments & Surgery
Animal · 2024
Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice
Hao M et al. · Experimental Cell Research · cited by Peptides
Meta-analysis · 2024 · n=1,315
Effects of therapeutic ultrasound in patients with knee osteoarthritis: A systematic review and meta-analysis
Luo Y et al. · Heliyon · cited by Light, Heat & Devices
Meta-analysis · 2024
Ultrasound therapy for pain reduction in musculoskeletal disorders: a systematic review and meta-analysis
Guan H et al. · Therapeutic Advances in Chronic Disease · cited by Light, Heat & Devices
In vitro · 2023
[The influence of peptides on the chondrogenic differentiation of human mesenchymal stem cells during replicative aging.]
Myakisheva SN et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
In vitro · 2023
[Peptides prevent the forming of secretory phenotype of chondrocytes associated with the aging.]
Myakisheva SN et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Review · 2023
Peptide Regulation of Chondrogenic Stem Cell Differentiation
Linkova N et al. · International Journal of Molecular Sciences · cited by Peptides
In vitro · 2023
Feasibility of Transport of 26 Biologically Active Ultrashort Peptides via LAT and PEPT Family Transporters
Khavinson VK et al. · Biomolecules · cited by Peptides
RCT · 2023 · n=160
Randomized, double-blind, four-arm pilot study on the effects of chicken essence and type II collagen hydrolysate on joint, bone, and muscle functions
Chen CC et al. · Nutrition Journal · cited by Foods & Nutrition
Meta-analysis · 2023 · n=507
Analgesic efficacy of collagen peptide in knee osteoarthritis: a meta-analysis of randomized controlled trials
Lin CR et al. · Journal of Orthopaedic Surgery and Research · cited by Supplements
RCT · 2023 · n=39
The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training
Balshaw TG et al. · Medicine and Science in Sports and Exercise · cited by Supplements
RCT · 2023 · n=50
Specific collagen peptides increase adaptions of patellar tendon morphology following 14-weeks of high-load resistance training: A randomized-controlled trial
Jerger S et al. · European Journal of Sport Science · cited by Supplements
RCT · 2023 · n=86
Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults
Kviatkovsky SA et al. · Journal of the International Society of Sports Nutrition · cited by Supplements
Meta-analysis · 2023 · n=2,646
Exercise Therapy for Knee Osteoarthritis: A Systematic Review and Network Meta-analysis
Mo L et al. · Orthopaedic Journal of Sports Medicine · cited by Exercise & Rehab
Meta-analysis · 2023
The Prevalence of Kashin-Beck Disease in China: a Systematic Review and Meta-analysis
Xu J et al. · Biological Trace Element Research · cited by Foods & Nutrition
Meta-analysis · 2023
The Causal Association between Alcohol, Smoking, Coffee Consumption, and the Risk of Arthritis: A Meta-Analysis of Mendelian Randomization Studies
Wang J et al. · Nutrients · cited by Foods & Nutrition
RCT · 2023 · n=282
Efficacy and safety of tart cherry supplementary citrate mixture on gout patients: a prospective, randomized, controlled study
Wang C et al. · Arthritis Research & Therapy · cited by Foods & Nutrition
Case series · 2023 · n=12
Pharmacokinetics and Pharmacodynamics of Anthocyanins after Administration of Tart Cherry Juice to Individuals with Gout
Brunetti L et al. · Molecular Nutrition & Food Research · cited by Foods & Nutrition
RCT · 2023 · n=45
Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates
Aussieker T et al. · Medicine and Science in Sports and Exercise · cited by Foods & Nutrition and Supplements
In vitro · 2023
Characterization of Low-Molecular-Weight Collagen from Korean Native Chicken Feet Hydrolyzed Using Alcalase
Woo H et al. · Journal of Microbiology and Biotechnology · cited by Foods & Nutrition
In vitro · 2023
Using high-temperature cooking for different times for bone soup: Physicochemical properties, protein oxidation and nutritional value
Ma C et al. · Journal of Food Composition and Analysis · cited by Foods & Nutrition
Animal · 2023
Glycyl-l-histidyl-l-lysine-Cu(2+) rescues cigarette smoking-induced skeletal muscle dysfunction via a sirtuin 1-dependent pathway
Deng M et al. · Journal of Cachexia, Sarcopenia and Muscle · cited by Peptides
RCT · 2023 · n=480
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
Mautner K et al. · Nature Medicine · cited by Injections
RCT · 2023 · n=14
Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study
Akasaka H et al. · Geriatrics & Gerontology International · cited by Supplements
RCT · 2023 · n=30
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study
Pencina KM et al. · The Journal of Clinical Endocrinology and Metabolism · cited by Supplements
RCT · 2023 · n=36
Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial
Katayoshi T et al. · Scientific Reports · cited by Supplements
Meta-analysis · 2023 · n=31,783
Meniscectomy is associated with a higher rate of osteoarthritis compared to meniscal repair following acute tears: a meta-analysis
Migliorini F et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Treatments & Surgery
Meta-analysis · 2023 · n=2,184
Risk Factors for Graft Failure After Meniscal Allograft Transplantation: A Systematic Review and Meta-analysis
Kunze KN et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
Cohort · 2023 · n=38
The effect of pentosan polysulfate sodium for improving dyslipidaemia and knee pain in people with knee osteoarthritis: A pilot study
Liu X et al. · Osteoarthritis and Cartilage Open · cited by Peptides
Review · 2023
Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
Smith MM et al. · Pharmaceuticals (Basel) · cited by Peptides
Review · 2023
Chondrocytes secretory phenotype associated with aging: role in the pathogenesis of osteoarthritis and prospects for peptide bioregulation
Myakisheva SN et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Animal · 2023 · n=12
Synovial fluid mitochondrial DNA concentration reflects the degree of cartilage damage after naturally occurring articular injury
Seewald LA et al. · Osteoarthritis and Cartilage · cited by Peptides
RCT · 2023 · n=218
Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial
Karaa A et al. · Neurology · cited by Peptides
In vitro · 2023
Pentosan polysulfate sodium promotes redifferentiation to the original phenotype in micromass-cultured canine articular chondrocytes and exerts molecular weight-dependent effects
Wang Y et al. · The Journal of Veterinary Medical Science · cited by Peptides
In vitro · 2023
Chemical and biological differences between original and mimetic pentosan polysulfates
Lenhart D et al. · Carbohydrate Polymers · cited by Peptides
Review · 2023
The Mechanisms and Efficacy of Photobiomodulation Therapy for Arthritis: A Comprehensive Review
Zhang R et al. · International Journal of Molecular Sciences · cited by Light, Heat & Devices
Animal · 2023
Photobiomodulation ameliorates inflammatory parameters in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis
Ryu JH et al. · Frontiers in Immunology · cited by Light, Heat & Devices
RCT · 2023 · n=18
Effects of extracorporeal shockwave therapy for mild knee osteoarthritis: A pilot study
Choi IJ et al. · Medicine · cited by Light, Heat & Devices
Case series · 2023 · n=10
Liver Injury Associated with Turmeric-A Growing Problem: Ten Cases from the Drug-Induced Liver Injury Network [DILIN]
Halegoua-DeMarzio D et al. · The American Journal of Medicine · cited by Supplements
Meta-analysis · 2023
Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials
Dehzad MJ et al. · Cytokine · cited by Supplements
RCT · 2023 · n=200
Efficacy and safety of curcumin in maintaining remission during disease-modifying antirheumatic drug withdrawal in rheumatoid arthritis at 52 weeks: a phase III double-blind, randomized placebo-controlled trial
Bhat SS et al. · Rheumatology International · cited by Supplements
Meta-analysis · 2023 · n=3,077
Relationship between 25-hydroxy vitamin D and knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Wang R et al. · Frontiers in Medicine · cited by Supplements
Cohort · 2023
Associations of Homocysteine, Folate, and Vitamin B12 with Osteoarthritis: A Mendelian Randomization Study
Hong H et al. · Nutrients · cited by Supplements
RCT · 2023 · n=80
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial
Yi L et al. · GeroScience · cited by Supplements
Animal · 2023
Targeting CD38 to Suppress Osteoarthritis Development and Associated Pain After Joint Injury in Mice
Gil Alabarse P et al. · Arthritis & Rheumatology · cited by Supplements
Animal · 2023 · n=20
The Potential Benefic Effect of Nicotinamide Riboside in Treating a Murine Model of Monoiodoacetate-Induced Knee Osteoarthritis
Gherghina FL et al. · Journal of Clinical Medicine · cited by Supplements
Cohort · 2023 · n=474
The influence of zinc and iron intake on osteoarthritis patients' subchondral sclerosis progression: A prospective observational study using data from the osteoarthritis Initiative
Zheng Z et al. · Heliyon · cited by Supplements
Cohort · 2023 · n=4,200
The Daily Intake Levels of Copper, Selenium, and Zinc Are Associated with Osteoarthritis but Not with Rheumatoid Arthritis in a Cross-sectional Study
Yang WM et al. · Biological Trace Element Research · cited by Supplements
RCT · 2023 · n=92
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Lu XT et al. · European Journal of Nutrition · cited by Supplements
Meta-analysis · 2023 · n=277
Effects of betaine supplementation on inflammatory markers: a systematic review and meta-analysis of randomised controlled trials
Xu J et al. · International Journal of Food Sciences and Nutrition · cited by Supplements
RCT · 2023 · n=40
Effect of vitamin K supplementation on serum calcification propensity and arterial stiffness in vitamin K-deficient kidney transplant recipients: A double-blind, randomized, placebo-controlled clinical trial
Eelderink C et al. · American Journal of Transplantation · cited by Supplements
Cohort · 2023 · n=259
Associations Between Dietary Intake of Vitamin K and Changes in Symptomatic and Structural Changes in Patients With Knee Osteoarthritis
Liao Z et al. · Arthritis Care & Research · cited by Foods & Nutrition and Supplements
Cohort · 2023 · n=94
An Exploratory Case-Control Study on the Associations of Bacterially-Derived Vitamin K Forms with the Intestinal Microbiome and Obesity-Related Osteoarthritis
Liu M et al. · Current Developments in Nutrition · cited by Supplements
RCT · 2023 · n=450
Study protocol of the InterVitaminK trial: a Danish population-based randomised double-blinded placebo-controlled trial of the effects of vitamin K (menaquinone-7) supplementation on cardiovascular, metabolic and bone health
Kampmann FB et al. · BMJ Open · cited by Supplements
In vitro · 2023
Positive Regulation of S-Adenosylmethionine on Chondrocytic Differentiation via Stimulation of Polyamine Production and the Gene Expression of Chondrogenic Differentiation Factors
Hoang LD et al. · International Journal of Molecular Sciences · cited by Supplements
RCT · 2023 · n=120
The short-term effect of glucosamine-sulfate, nonanimal chondroitin-sulfate, and S-adenosylmethionine combination on ultrasonography findings, inflammation, pain, and functionality in patients with knee osteoarthritis: A pilot, double-blind, randomized, placebo-controlled clinical trial
Veličković Z et al. · Archives of Rheumatology · cited by Supplements
RCT · 2023 · n=251
Aragonite-Based Scaffold Versus Microfracture and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicenter Randomized Controlled Trial
Altschuler N et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
Animal · 2023
Thymosin β4 and prothymosin α promote cardiac regeneration post-ischaemic injury in mice
Gladka MM et al. · Cardiovascular Research · cited by Peptides
Animal · 2023
Targeted Deletion of Thymosin Beta 4 in Hepatic Stellate Cells Ameliorates Liver Fibrosis in a Transgenic Mouse Model
Kim J et al. · Cells · cited by Peptides
Animal · 2023 · n=4
Low-intensity pulsed ultrasound irradiation attenuates collagen degradation of articular cartilage in early osteoarthritis-like model mice
Kojima Y et al. · Journal of Experimental Orthopaedics · cited by Light, Heat & Devices
Case series · 2022
[Bioregulation therapy in the treatment of age-related osteoarthropathy of the temporomandibular joint.]
Serikov AA et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
In vitro · 2022
Short Peptides Induce Development of Root Hair Nicotiana tabacum
Fedoreyeva LI et al. · Plants · cited by Peptides
In vitro · 2022
Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro
Yue X et al. · Aging (Albany NY) · cited by Peptides
Animal · 2022
Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy
Perovic D et al. · Current Issues in Molecular Biology · cited by Peptides
Animal · 2022
Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs
He L et al. · Frontiers in Pharmacology · cited by Peptides
Animal · 2022
The anti-nociceptive effect of BPC-157 on the incisional pain model in rats
Jung YH et al. · Journal of Dental Anesthesia and Pain Medicine · cited by Peptides
RCT · 2022 · n=9
Comparison of gelatin and low-molecular weight gelatin hydrolysate ingestion on hydroxyproline (Hyp), Pro-Hyp and Hyp-Gly concentrations in human blood
Iwasaki Y et al. · Food Chemistry · cited by Foods & Nutrition and Supplements
RCT · 2022 · n=27
Effects of specific collagen peptide supplementation combined with resistance training on Achilles tendon properties
Jerger S et al. · Scandinavian Journal of Medicine & Science in Sports · cited by Supplements
RCT · 2022 · n=98
Does vitamin C supplementation improve rotator cuff healing? A preliminary study
Martel M et al. · European Journal of Orthopaedic Surgery & Traumatology · cited by Supplements
Cohort · 2022 · n=1,212
Association Between Walking for Exercise and Symptomatic and Structural Progression in Individuals With Knee Osteoarthritis: Data From the Osteoarthritis Initiative Cohort
Lo GH et al. · Arthritis & Rheumatology · cited by Exercise & Rehab
RCT · 2022 · n=235
Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial
Stonehouse W et al. · The American Journal of Clinical Nutrition · cited by Foods & Nutrition
Cohort · 2022 · n=5,503
Analysis of correlation between the consumption of beverages and the risk of radiographic knee osteoarthritis in Korean people: A cross-sectional study using the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V-1, 2)
Lim CO et al. · Medicine (Baltimore) · cited by Foods & Nutrition
Cohort · 2022 · n=1,249
Dietary inflammation index and osteoarthritis in the elderly: is there a mediating role of physical activity?
Wang H et al. · The British Journal of Nutrition · cited by Foods & Nutrition
Case series · 2022 · n=28
An anti-inflammatory diet intervention for knee osteoarthritis: a feasibility study
Cooper I et al. · BMC Musculoskeletal Disorders · cited by Foods & Nutrition
Review · 2022
Do Pomegranate Hydrolyzable Tannins and Their Derived Metabolites Provide Relief in Osteoarthritis? Findings from a Scoping Review
Govoni M et al. · Molecules · cited by Foods & Nutrition
In vitro · 2022
Thermo-Responsive Gel Containing Hydroxytyrosol-Chitosan Nanoparticles (Hyt@tgel) Counteracts the Increase of Osteoarthritis Biomarkers in Human Chondrocytes
Valentino A et al. · Antioxidants (Basel) · cited by Foods & Nutrition
Cohort · 2022 · n=50,508
Genetically predicted tea intake increases the risk of osteoarthritis: A Mendelian randomization study
Li G et al. · Frontiers in Genetics · cited by Foods & Nutrition
Meta-analysis · 2022
A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms
Mathieu S et al. · Nutrients · cited by Foods & Nutrition and Supplements
Animal · 2022
Components of tart cherry juice inhibit NFκB activation and inflammation in acute gout
Schlesinger N et al. · Clinical and Experimental Rheumatology · cited by Foods & Nutrition
RCT · 2022 · n=50
Collagen and Vitamin C Supplementation Increases Lower Limb Rate of Force Development
Lis DM et al. · International Journal of Sport Nutrition and Exercise Metabolism · cited by Foods & Nutrition
Review · 2022
The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review
Holwerda AM et al. · Nutrition Reviews · cited by Foods & Nutrition and Supplements
Animal · 2022
Biomimetic Hydrogel Scaffolds with Copper Peptide-Functionalized RADA16 Nanofiber Improve Wound Healing in Diabetes
Yang X et al. · Macromolecular Bioscience · cited by Peptides
RCT · 2022 · n=90
Bone Marrow Aspirate Concentrate Is Equivalent to Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis at 2 Years: A Prospective Randomized Trial
Anz AW et al. · The American Journal of Sports Medicine · cited by Injections
Systematic review · 2022 · n=299
Bone Marrow Aspirate Concentrate for the Treatment of Knee Osteoarthritis: A Systematic Review
Keeling LE et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2022 · n=118
Microfragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Prospective Randomized Controlled Trial at 2-Year Follow-up
Zaffagnini S et al. · The American Journal of Sports Medicine · cited by Injections
Meta-analysis · 2022 · n=21,163
Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis
Pereira TV et al. · BMJ · cited by Injections
Review · 2022
AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition
Brophy RH et al. · The Journal of the American Academy of Orthopaedic Surgeons · cited by Injections
Meta-analysis · 2022 · n=978
Effectiveness, Compliance, and Safety of Dextrose Prolotherapy for Knee Osteoarthritis: A Meta-Analysis and Metaregression of Randomized Controlled Trials
Chen YW et al. · Clinical Rehabilitation · cited by Injections
RCT · 2022 · n=30
Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects
Okabe K et al. · Frontiers in Nutrition · cited by Supplements
RCT · 2022 · n=108
Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study
Kim M et al. · Nutrients · cited by Supplements
RCT · 2022 · n=32
A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals
Jensen JB et al. · JCI Insight · cited by Supplements
RCT · 2022 · n=321
Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial
Noorduyn JCA et al. · JAMA Network Open · cited by Treatments & Surgery
RCT · 2022 · n=100
Arthroscopic partial meniscectomy versus physical therapy for traumatic meniscal tears in a young study population: a randomised controlled trial
van der Graaff SJA et al. · British Journal of Sports Medicine · cited by Treatments & Surgery
Systematic review · 2022 · n=12
A systematic review about long-term results after meniscus repair
Petersen W et al. · Archives of Orthopaedic and Trauma Surgery · cited by Treatments & Surgery
Case series · 2022 · n=61
Outcomes, Complications, and Reoperations After Meniscal Allograft Transplantation
Vasta S et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
Case series · 2022 · n=4
Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
Parker LA et al. · Case Reports in Veterinary Medicine · cited by Peptides
Meta-analysis · 2022 · n=1,670
Efficacy and safety of curcuminoids alone in alleviating pain and dysfunction for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Feng J et al. · BMC Complementary Medicine and Therapies · cited by Supplements
RCT · 2022 · n=24
Superior Bioavailability of a Novel Curcumin Formulation in Healthy Humans Under Fasting Conditions
Kothaplly S et al. · Advances in Therapy · cited by Supplements
RCT · 2022 · n=96
UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study
Schön C et al. · Journal of Integrative and Complementary Medicine · cited by Supplements
Animal · 2022 · n=48
Improvement of tissue-specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol
Bai LB et al. · Pharmacology Research & Perspectives · cited by Supplements
RCT · 2022 · n=42
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men
Igarashi M et al. · NPJ Aging · cited by Supplements
RCT · 2022 · n=31
Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women
Fukamizu Y et al. · Scientific Reports · cited by Supplements
Registry · 2022 · n=130
Postauthorization safety study of betaine anhydrous
Mütze U et al. · Journal of Inherited Metabolic Disease · cited by Supplements
RCT · 2022 · n=365
Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial
Diederichsen ACP et al. · Circulation · cited by Supplements
Cohort · 2022 · n=826,690
Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study
Zhao SS et al. · Seminars in Arthritis and Rheumatism · cited by Supplements
Case series · 2022 · n=125
10-Year Survival Rates After High Tibial Osteotomy Using Angular Stable Internal Plate Fixation: Case Series With Subgroup Analysis of Outcomes After Combined Autologous Chondrocyte Implantation and High Tibial Osteotomy
Bode L et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
RCT · 2022 · n=18
0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial
Sosne G et al. · International Journal of Molecular Sciences · cited by Peptides
Meta-analysis · 2022 · n=807
Effects of low-intensity pulsed ultrasound on knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials
Chen H et al. · Clinical Rehabilitation · cited by Light, Heat & Devices
Meta-analysis · 2022 · n=423
A systematic review and meta-analysis of the effect of phonophoresis on patients with knee osteoarthritis
Yang FA et al. · Scientific Reports · cited by Light, Heat & Devices
Cohort · 2021 · n=2,955
[Efficacy of combined use of glycosaminoglycan peptide complex for intramuscular administration and oral diacerein in osteoarthritis: evaluation according to an observational multicenter clinical trial]
Karateev AE et al. · Terapevticheskii Arkhiv · cited by Peptides
Review · 2021
Melatonin: Effects on Cartilage Homeostasis and Therapeutic Prospects in Cartilage-related Diseases
Xie WQ et al. · Aging Dis · cited by Peptides
Animal · 2021
Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats
Japjec M et al. · Biomedicines · cited by Peptides
Case series · 2021 · n=31
Specific Bioactive Collagen Peptides in Osteopenia and Osteoporosis: Long-Term Observation in Postmenopausal Women
Zdzieblik D et al. · Journal of Bone Metabolism · cited by Supplements
RCT · 2021 · n=180
The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial
Zdzieblik D et al. · Nutrients · cited by Supplements
Systematic review · 2021 · n=37
Management of patellar tendinopathy: a systematic review and network meta-analysis of randomised studies
Challoumas D et al. · BMJ Open Sport & Exercise Medicine · cited by Exercise & Rehab
Cohort · 2021 · n=392
Associations between diet quality and knee joint structures, symptoms and systemic abnormalities in people with symptomatic knee osteoarthritis
Ruan G et al. · Clinical Nutrition · cited by Foods & Nutrition
Review · 2021
Magnesium in joint health and osteoarthritis
Kuang X et al. · Nutrition Research · cited by Foods & Nutrition
Cohort · 2021 · n=63,129
Food sources of dietary fibre and risk of total knee replacement related to severe osteoarthritis, the Singapore Chinese Health Study
Leung YY et al. · RMD Open · cited by Foods & Nutrition
Meta-analysis · 2021 · n=25,192
The association between alcohol consumption and osteoarthritis: a meta-analysis and meta-regression of observational studies
To K et al. · Rheumatology International · cited by Foods & Nutrition
Cohort · 2021 · n=50,508
Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study
Zhang Y et al. · Frontiers in Endocrinology · cited by Foods & Nutrition
RCT · 2021 · n=58
Thirty Days of Montmorency Tart Cherry Supplementation Has No Effect on Gut Microbiome Composition, Inflammation, or Glycemic Control in Healthy Adults
Hillman AR et al. · Frontiers in Nutrition · cited by Foods & Nutrition
In vitro · 2021
Chondroprotective effects of purple corn anthocyanins on advanced glycation end products induction through suppression of NF-κB and MAPK signaling
Chuntakaruk H et al. · Scientific Reports · cited by Foods & Nutrition
Systematic review · 2021
Systematic review of the effects of pomegranate (Punica granatum) on osteoarthritis
Malek Mahdavi A et al. · Health Promotion Perspectives · cited by Foods & Nutrition
Animal · 2021
Punicalin alleviates TNF-α- and IL-1β-induced chondrocyte dysfunction and cartilage metabolism via mediating FOXO3 signaling axis
Yang L et al. · Journal of Food Biochemistry · cited by Foods & Nutrition
Animal · 2021
Sulforaphane protects against oxidative stress-induced apoptosis via activating SIRT1 in mouse osteoarthritis
Chen M et al. · Molecular Medicine Reports · cited by Foods & Nutrition
Animal · 2021 · n=34
Dietary Oleocanthal Supplementation Prevents Inflammation and Oxidative Stress in Collagen-Induced Arthritis in Mice
Montoya T et al. · Antioxidants (Basel) · cited by Foods & Nutrition
Animal · 2021 · n=24
Analysis of the Anti-Inflammatory Capacity of Bone Broth in a Murine Model of Ulcerative Colitis
Mar-Solís LM et al. · Medicina (Kaunas) · cited by Foods & Nutrition
In vitro · 2021
Enhanced angiogenic effects of RGD, GHK peptides and copper (II) compositions in synthetic cryogel ECM model
Zoughaib M et al. · Materials Science and Engineering C · cited by Peptides
In vitro · 2021
Ternary Cu(2+) Complexes of Human Serum Albumin and Glycyl-l-histidyl-l-lysine
Bossak-Ahmad K et al. · Inorganic Chemistry · cited by Peptides
RCT · 2021 · n=288
Effect of Intra-articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients With Knee Osteoarthritis: The RESTORE Randomized Clinical Trial
Bennell KL et al. · JAMA · cited by Injections
Meta-analysis · 2021 · n=1,608
Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Belk JW et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2021 · n=150
Platelet-rich plasma (PRP) in osteoarthritis (OA) knee: Correct dose critical for long term clinical efficacy
Bansal H et al. · Scientific Reports · cited by Injections
Cohort · 2021 · n=175
Bone Marrow Aspirate Concentrate versus Platelet Rich Plasma or Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Dulic O et al. · Medicina (Kaunas) · cited by Injections
Review · 2021
NAD(+) metabolism and its roles in cellular processes during ageing
Covarrubias AJ et al. · Nature Reviews Molecular Cell Biology · cited by Supplements
RCT · 2021 · n=48
Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study
Liao B et al. · Journal of the International Society of Sports Nutrition · cited by Supplements
Meta-analysis · 2021 · n=30
Hypoglycemic Effect of Resveratrol: A Systematic Review and Meta-Analysis
García-Martínez BI et al. · Antioxidants · cited by Supplements
Animal · 2021
Restoration of energy homeostasis by SIRT6 extends healthy lifespan
Roichman A et al. · Nature Communications · cited by Supplements
Systematic review · 2021 · n=10
Common elective orthopaedic procedures and their clinical effectiveness: umbrella review of level 1 evidence
Blom AW et al. · BMJ · cited by Treatments & Surgery
Meta-analysis · 2021 · n=691
Effect of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Peng L et al. · Frontiers in Medicine · cited by Light, Heat & Devices
Systematic review · 2021
A Comparison of Neuromuscular Electrical Stimulation Parameters for Postoperative Quadriceps Strength in Patients After Knee Surgery: A Systematic Review
Conley CEW et al. · Sports Health · cited by Light, Heat & Devices
Case series · 2021 · n=16
Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain
Lee E et al. · Alternative Therapies in Health and Medicine · cited by Peptides
Registry · 2021 · n=602
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain (PARA_OA_002)
Paradigm Biopharmaceuticals · ClinicalTrials.gov registration · cited by Peptides
RCT · 2021 · n=12
A phase 2/3 randomized clinical trial followed by an open-label extension to evaluate the effectiveness of elamipretide in Barth syndrome, a genetic disorder of mitochondrial cardiolipin metabolism
Reid Thompson W et al. · Genetics in Medicine · cited by Peptides
RCT · 2021 · n=20
Pentosan polysulfate sodium for Ross River virus-induced arthralgia: a phase 2a, randomized, double-blind, placebo-controlled study
Krishnan R et al. · BMC Musculoskeletal Disorders · cited by Peptides
Case report · 2021 · n=1
Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
Tong MX et al. · JFMS Open Reports · cited by Peptides
Systematic review · 2021 · n=33
In Vitro and In Vivo Effects of Light Therapy on Cartilage Regeneration for Knee Osteoarthritis: A Systematic Review
Oliveira S et al. · Cartilage · cited by Light, Heat & Devices, Injections and Supplements
RCT · 2021 · n=101
An Investigation into the Effects of a Curcumin Extract (Curcugen) on Osteoarthritis Pain of the Knee: A Randomised, Double-Blind, Placebo-Controlled Study
Lopresti AL et al. · Nutrients · cited by Supplements
RCT · 2021 · n=72
Influence of a low-dose supplementation of curcumagalactomannoside complex (CurQfen) in knee osteoarthritis: A randomized, open-labeled, active-controlled clinical trial
Thomas JV et al. · Phytotherapy Research · cited by Supplements
RCT · 2021 · n=68
Acute Effects of Turmeric Extracts on Knee Joint Pain: A Pilot, Randomized Controlled Trial
Calderón-Pérez L et al. · Journal of Medicinal Food · cited by Supplements
Meta-analysis · 2021 · n=1,810
Efficacy and Safety of Turmeric Extracts for the Treatment of Knee Osteoarthritis: a Systematic Review and Meta-analysis of Randomised Controlled Trials
Wang Z et al. · Current Rheumatology Reports · cited by Supplements
Meta-analysis · 2021 · n=1,258
The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Hsiao AF et al. · Complementary Therapies in Medicine · cited by Supplements
RCT · 2021 · n=12
Increasing Post-Digestive Solubility of Curcumin Is the Most Successful Strategy to Improve its Oral Bioavailability: A Randomized Cross-Over Trial in Healthy Adults and In Vitro Bioaccessibility Experiments
Flory S et al. · Molecular Nutrition & Food Research · cited by Supplements
RCT · 2021 · n=24
Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects
Chung H et al. · International Journal of Clinical Pharmacology and Therapeutics · cited by Supplements
Systematic review · 2021 · n=30
Acute liver injury following turmeric use in Tuscany: An analysis of the Italian Phytovigilance database and systematic review of case reports
Lombardi N et al. · British Journal of Clinical Pharmacology · cited by Supplements
RCT · 2021 · n=110
Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam
Marouf BH et al. · Indian Journal of Pharmacology · cited by Supplements
Animal · 2021
Betaine Attenuates Osteoarthritis by Inhibiting Osteoclastogenesis and Angiogenesis in Subchondral Bone
Yajun W et al. · Frontiers in Pharmacology · cited by Supplements
RCT · 2021 · n=25
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Yoshino M et al. · Science · cited by Supplements
Meta-analysis · 2021
Betaine Supplementation Moderately Increases Total Cholesterol Levels: A Systematic Review and Meta-Analysis
Zawieja EE et al. · Journal of Dietary Supplements · cited by Supplements
Cohort · 2021 · n=3,494
Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis
Boer CG et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition and Supplements
Cohort · 2021 · n=4,285
Warfarin use and risk of knee and hip replacements
Ballal P et al. · Annals of the Rheumatic Diseases · cited by Supplements
Cohort · 2021 · n=1,977
The association between vitamin K and medial tibial-femoral knee osteoarthritis progression: Data from the osteoarthritis initiative
Horace RW et al. · Osteoarthritis and Cartilage Open · cited by Supplements
Cohort · 2021 · n=450
Vitamin K and D Status in Patients with Knee Osteoarthritis: An Analytical Cross-sectional Study
Askari A et al. · Mediterranean Journal of Rheumatology · cited by Supplements
Case series · 2021 · n=87
Long-term Prospective Clinical and Magnetic Resonance Imaging-Based Evaluation of Matrix-Induced Autologous Chondrocyte Implantation
Ebert JR et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
RCT · 2021 · n=35
An accelerated 6-week return to full weight bearing after matrix-induced autologous chondrocyte implantation results in good clinical outcomes to 5 years post-surgery
Ebert JR et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Treatments & Surgery
Case series · 2021 · n=24
High-Density Autologous Chondrocyte Implantation as Treatment for Ankle Osteochondral Defects
López-Alcorocho JM et al. · Cartilage · cited by Treatments & Surgery
Cohort · 2021 · n=86
Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions in Mild to Moderate Osteoarthritic Knees: Results of a 2-Year Multicenter Prospective Study
Kon E et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
RCT · 2021 · n=84
A first-in-human, randomized, double-blind, single- and multiple-dose, phase I study of recombinant human thymosin β4 in healthy Chinese volunteers
Wang X et al. · Journal of Cellular and Molecular Medicine · cited by Peptides
Animal · 2021
In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis
An HW et al. · Molecular Carcinogenesis · cited by Peptides
Meta-analysis · 2021 · n=264
Therapeutic ultrasound for knee osteoarthritis: A systematic review and meta-analysis with grade quality assessment
Dantas LO et al. · Brazilian Journal of Physical Therapy · cited by Light, Heat & Devices
Animal · 2021
Low-Intensity Pulsed Ultrasound Alleviates Osteoarthritis Condition Through Focal Adhesion Kinase-Mediated Chondrocyte Proliferation and Differentiation
Sang F et al. · Cartilage · cited by Light, Heat & Devices
Review · 2020
[Age features of bioregulatory therapy of dental diseases.]
Pinelis IS et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
In vitro · 2020
Identification of short peptides as part of polypeptide complexes isolated from animal organs
Zhurkovich IK et al. · Uspekhi Sovremennoi Biologii (Biology Bulletin Reviews) · cited by Peptides
In vitro · 2020
Comparison of the Effects of KE and AED Peptides on Functional Activity of Human Skin Fibroblasts during Their Replicative Aging
Fridman NV et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
In vitro · 2020
Short Peptides Protect Oral Stem Cells from Ageing
Sinjari B et al. · Stem Cell Reviews and Reports · cited by Peptides
In vitro · 2020
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
Khavinson V et al. · Molecules · cited by Peptides
Review · 2020
Telomere length and telomerase activity in osteoporosis and osteoarthritis
Fragkiadaki P et al. · Exp Ther Med · cited by Peptides
In vitro · 2020
Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway
Hsieh MJ et al. · Scientific Reports · cited by Peptides
Animal · 2020
Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157
Wu H et al. · Drug Design, Development and Therapy · cited by Peptides
Systematic review · 2020
Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping
Honvo G et al. · Rheumatology and Therapy · cited by Supplements
RCT · 2020 · n=22
Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial
Oikawa SY et al. · The American Journal of Clinical Nutrition · cited by Supplements
Cohort · 2020 · n=1,785
Associations Between Vitamins C and D Intake and Cartilage Composition and Knee Joint Morphology Over 4 Years: Data From the Osteoarthritis Initiative
Joseph GB et al. · Arthritis Care & Research · cited by Supplements
RCT · 2020 · n=91
Isometric exercises do not provide immediate pain relief in Achilles tendinopathy: A quasi-randomized clinical trial
van der Vlist AC et al. · Scandinavian Journal of Medicine & Science in Sports · cited by Exercise & Rehab
Systematic review · 2020 · n=10
Effectiveness of isometric exercise in the management of tendinopathy: a systematic review and meta-analysis of randomised trials
Clifford C et al. · BMJ Open Sport & Exercise Medicine · cited by Exercise & Rehab
Systematic review · 2020 · n=6
Effects of exercise therapy on joint instability in patients with osteoarthritis of the knee: A systematic review
Kawabata S et al. · Osteoarthritis and Cartilage Open · cited by Exercise & Rehab
RCT · 2020 · n=120
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
Sasahara I et al. · The Journal of Nutrition · cited by Foods & Nutrition
RCT · 2020 · n=80
Oral intake of Streptococcus thermophilus improves knee osteoarthritis degeneration: A randomized, double-blind, placebo-controlled clinical study
Lyu JL et al. · Heliyon · cited by Foods & Nutrition
Cohort · 2020 · n=1,323
Vitamin K Status and Mobility Limitation and Disability in Older Adults: The Health, Aging, and Body Composition Study
Shea MK et al. · The Journals of Gerontology. Series A · cited by Foods & Nutrition
Registry · 2020 · n=574,925
Endemic Kashin-Beck disease: A food-sourced osteoarthropathy
Wang K et al. · Seminars in Arthritis and Rheumatism · cited by Foods & Nutrition
Review · 2020
The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies
Kang D et al. · Experimental & Molecular Medicine · cited by Foods & Nutrition
RCT · 2020 · n=21
The Effect of Low-Carbohydrate and Low-Fat Diets on Pain in Individuals with Knee Osteoarthritis
Strath LJ et al. · Pain Medicine · cited by Foods & Nutrition
Systematic review · 2020
The effects of weight loss on imaging outcomes in osteoarthritis of the hip or knee in people who are overweight or obese: a systematic review
Daugaard CL et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
RCT · 2020 · n=50
Lack of effect of tart cherry concentrate dose on serum urate in people with gout
Stamp LK et al. · Rheumatology (Oxford) · cited by Foods & Nutrition
RCT · 2020
Effect of tart cherry juice on risk of gout attacks: protocol for a randomised controlled trial
Lamb KL et al. · BMJ Open · cited by Foods & Nutrition
RCT · 2020 · n=60
The Effectiveness of Olive Oil in Controlling Morning Inflammatory Pain of Phalanges and Knees Among Women With Rheumatoid Arthritis: A Randomized Clinical Trial
Hekmatpou D et al. · Rehabilitation Nursing · cited by Foods & Nutrition
Animal · 2020 · n=36
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model
Huang HT et al. · Antioxidants (Basel) · cited by Foods & Nutrition
Review · 2020
Effects of Nutritional Interventions in the Control of Musculoskeletal Pain: An Integrative Review
Mendonça CR et al. · Nutrients · cited by Foods & Nutrition
Meta-analysis · 2020
Effectiveness of Ginger on Pain and Function in Knee Osteoarthritis: A PRISMA Systematic Review and Meta-Analysis
Araya-Quintanilla F et al. · Pain Physician · cited by Supplements
In vitro · 2020
Valorization of Chicken Feet By-Product of the Poultry Industry: High Qualities of Gelatin and Biofilm from Extraction of Collagen
Santana JCC et al. · Polymers · cited by Foods & Nutrition
In vitro · 2020
Extraction and characterization of gelatin from black-bone chicken by-products
Saenmuang S et al. · Food Science and Biotechnology · cited by Foods & Nutrition
RCT · 2020 · n=19
The Use of Recombinant Human Growth Hormone to Protect Against Muscle Weakness in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Pilot, Randomized Placebo-Controlled Trial
Mendias CL et al. · The American Journal of Sports Medicine · cited by Peptides
In vitro · 2020
Enhanced biological properties of collagen/chitosan-coated poly(ε-caprolactone) scaffold by surface modification with GHK-Cu peptide and 58S bioglass
Molavi AM et al. · Progress in Biomaterials · cited by Peptides
Animal · 2020
Hydrogels based on low-methoxyl amidated citrus pectin and flaxseed gum formulated with tripeptide glycyl-l-histidyl-l-lysine improve the healing of experimental cutting wounds in rats
Synytsya A et al. · International Journal of Biological Macromolecules · cited by Peptides
Case series · 2020 · n=10
Combination Tripeptide/Hexapeptide Serum with 1540 nm Nonablative Fractional Laser for the Treatment of Striae Distensae: A Pilot Study
McGuinn KP et al. · Skinmed · cited by Peptides
RCT · 2020 · n=76
Efficacy of Intra-Articular Hypertonic Dextrose (Prolotherapy) for Knee Osteoarthritis: A Randomized Controlled Trial
Sit RWS et al. · Annals of Family Medicine · cited by Injections
Systematic review · 2020 · n=858
Oxygen-Ozone Therapy for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials
Sconza C et al. · Arthroscopy · cited by Injections
Case series · 2020 · n=10
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
Irie J et al. · Endocrine Journal · cited by Supplements
RCT · 2020 · n=13
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans
Remie CME et al. · The American Journal of Clinical Nutrition · cited by Supplements
Meta-analysis · 2020 · n=31
The effects of resveratrol on lipid profiles and liver enzymes in patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials
Akbari M et al. · Lipids in Health and Disease · cited by Supplements
Review · 2020 · n=27
Management of traumatic meniscus tears: the 2019 ESSKA meniscus consensus
Kopf S et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Treatments & Surgery
RCT · 2020 · n=146
Arthroscopic partial meniscectomy for a degenerative meniscus tear: a 5 year follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial
Sihvonen R et al. · British Journal of Sports Medicine · cited by Treatments & Surgery
Systematic review · 2020
Clinical and Radiological Outcomes of Meniscal Repair Versus Partial Meniscectomy for Medial Meniscus Root Tears: A Systematic Review and Meta-analysis
Ro KH et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
Cohort · 2020 · n=109
Meniscal allograft transplantation in The Netherlands: long-term survival, patient-reported outcomes, and their association with preoperative complaints and interventions
van der Wal RJP et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Treatments & Surgery
RCT · 2020 · n=21
Utility of Neuromuscular Electrical Stimulation to Preserve Quadriceps Muscle Fiber Size and Contractility After Anterior Cruciate Ligament Injuries and Reconstruction: A Randomized, Sham-Controlled, Blinded Trial
Toth MJ et al. · The American Journal of Sports Medicine · cited by Light, Heat & Devices
In vitro · 2020
Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides
Ashapkin V et al. · Molecular Biology Reports · cited by Peptides
In vitro · 2020
Mitoprotective therapy prevents rapid, strain-dependent mitochondrial dysfunction after articular cartilage injury
Bartell LR et al. · Journal of Orthopaedic Research · cited by Peptides
RCT · 2020 · n=71
Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial
Butler J et al. · Journal of Cardiac Failure · cited by Peptides
Meta-analysis · 2020 · n=4,674
Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis
Imamura M et al. · The Cochrane Database of Systematic Reviews · cited by Peptides
Review · 2020
Acute:Chronic Workload Ratio: Conceptual Issues and Fundamental Pitfalls
Impellizzeri FM et al. · International Journal of Sports Physiology and Performance · cited by Precautions
Review · 2020
Extracorporeal shockwave treatment in knee osteoarthritis: therapeutic effects and possible mechanism
An S et al. · Bioscience Reports · cited by Light, Heat & Devices
Meta-analysis · 2020 · n=545
Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis
Yu G et al. · BMC Complementary Medicine and Therapies · cited by Supplements
RCT · 2020 · n=70
Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion-Synovitis of Knee Osteoarthritis: A Randomized Trial
Wang Z et al. · Annals of Internal Medicine · cited by Supplements
RCT · 2020 · n=71
The Effect of Nanocurcumin in Improvement of Knee Osteoarthritis: A Randomized Clinical Trial
Hashemzadeh K et al. · Current Rheumatology Reviews · cited by Supplements
RCT · 2020 · n=30
Significant immunomodulatory properties of curcumin in patients with osteoarthritis; a successful clinical trial in Iran
Atabaki M et al. · International Immunopharmacology · cited by Supplements
RCT · 2020 · n=60
Herbal formulation "turmeric extract, black pepper, and ginger" versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial
Heidari-Beni M et al. · Phytotherapy Research · cited by Supplements
Review · 2020
The Relationship between Vitamin K and Osteoarthritis: A Review of Current Evidence
Chin KY · Nutrients · cited by Supplements
RCT · 2020 · n=1,398
The Effects of Vitamin D and Marine Omega-3 Fatty Acid Supplementation on Chronic Knee Pain in Older US Adults: Results From a Randomized Trial
MacFarlane LA et al. · Arthritis & Rheumatology · cited by Supplements
RCT · 2020 · n=29
Betaine Supplementation Does Not Improve Muscle Hypertrophy or Strength Following 6 Weeks of Cross-Fit Training
Moro T et al. · Nutrients · cited by Supplements
Systematic review · 2020 · n=1,011
S-Adenosylmethionine (SAMe) in major depressive disorder (MDD): a clinician-oriented systematic review
Cuomo A et al. · Annals of General Psychiatry · cited by Supplements
In vitro · 2020
Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/microfiber hybrid yarns for tendon tissue engineering application
Wu S et al. · Materials Science and Engineering C · cited by Peptides
Review · 2019
Prospects for using peptide bioregulators for prevention and treatment of age-associated diseases of the musculoskeletal system (review of experimental data)
Ryzhak GA et al. · Patogenez (Pathogenesis) · cited by Peptides
In vitro · 2019 · n=11
Effect of Peptide AEDG on Telomere Length and Mitotic Index of PHA-Stimulated Human Blood Lymphocytes
Khavinson VK et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
Animal · 2019
Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats
Perovic D et al. · Journal of Orthopaedic Surgery and Research · cited by Peptides
Animal · 2019
Intragastric Application of Aspirin, Clopidogrel, Cilostazol, and BPC 157 in Rats: Platelet Aggregation and Blood Clot
Konosic S et al. · Oxidative Medicine and Cellular Longevity · cited by Peptides
RCT · 2019 · n=20
Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients
Praet SFE et al. · Nutrients · cited by Supplements
In vitro · 2019
Food-Derived Collagen Peptides, Prolyl-Hydroxyproline (Pro-Hyp), and Hydroxyprolyl-Glycine (Hyp-Gly) Enhance Growth of Primary Cultured Mouse Skin Fibroblast Using Fetal Bovine Serum Free from Hydroxyprolyl Peptide
Asai TT et al. · International Journal of Molecular Sciences · cited by Supplements
Case series · 2019 · n=5
Theoretical and laboratory investigations of the effects of hydroxyproline ingestion on the metabolic and physicochemical risk factors for calcium oxalate kidney stone formation in a small group of healthy subjects
Rodgers A et al. · International Urology and Nephrology · cited by Supplements
Systematic review · 2019 · n=9
Impact of exercise on articular cartilage in people at risk of, or with established, knee osteoarthritis: a systematic review of randomised controlled trials
Bricca A et al. · British Journal of Sports Medicine · cited by Exercise & Rehab
Systematic review · 2019 · n=12
Impact of Exercise Therapy on Molecular Biomarkers Related to Cartilage and Inflammation in Individuals at Risk of, or With Established, Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Bricca A et al. · Arthritis Care & Research · cited by Exercise & Rehab
RCT · 2019 · n=28
Comparing the Effectiveness of Blood Flow Restriction and Traditional Heavy Load Resistance Training in the Post-Surgery Rehabilitation of Anterior Cruciate Ligament Reconstruction Patients: A UK National Health Service Randomised Controlled Trial
Hughes L et al. · Sports Medicine · cited by Exercise & Rehab
Meta-analysis · 2019 · n=238
Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis
Centner C et al. · Sports Medicine · cited by Exercise & Rehab
Animal · 2019 · n=12
Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration
NaPier Z et al. · Medical Science Monitor · cited by Foods & Nutrition
Animal · 2019
Protective effect of prebiotic and exercise intervention on knee health in a rat model of diet-induced obesity
Rios JL et al. · Scientific Reports · cited by Foods & Nutrition
Review · 2019
Gut microbiota and osteoarthritis management: An expert consensus of the European society for clinical and economic aspects of osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO)
Biver E et al. · Ageing Research Reviews · cited by Foods & Nutrition
RCT · 2019 · n=26
Consumption of 100% Tart Cherry Juice Reduces Serum Urate in Overweight and Obese Adults
Martin KR et al. · Current Developments in Nutrition · cited by Foods & Nutrition
Animal · 2019
Cyanidin ameliorates the progression of osteoarthritis via the Sirt6/NF-κB axis in vitro and in vivo
Jiang C et al. · Food & Function · cited by Foods & Nutrition
Systematic review · 2019
A systematic review of osteoarthritis prevention and management with dietary phytochemicals from foods
Guan VX et al. · Maturitas · cited by Foods & Nutrition
Case report · 2019 · n=1
A case of acute kidney injury secondary to black cherry concentrate in a patient with chronic kidney disease secondary to type 2 diabetes mellitus
Matout M et al. · CEN Case Reports · cited by Foods & Nutrition
Animal · 2019
Urolithin A targets the PI3K/Akt/NF-κB pathways and prevents IL-1β-induced inflammatory response in human osteoarthritis: in vitro and in vivo studies
Fu X et al. · Food & Function · cited by Foods & Nutrition
Cohort · 2019 · n=36
Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration
Fahey JW et al. · Nutrients · cited by Foods & Nutrition
Animal · 2019
Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis
Szychlinska MA et al. · European Journal of Nutrition · cited by Foods & Nutrition
In vitro · 2019
Hydroxytyrosol promotes autophagy by regulating SIRT1 against advanced oxidation protein product-induced NADPH oxidase and inflammatory response
Sun T et al. · International Journal of Molecular Medicine · cited by Foods & Nutrition
RCT · 2019 · n=63
Blueberries Improve Pain, Gait Performance, and Inflammation in Individuals with Symptomatic Knee Osteoarthritis
Du C et al. · Nutrients · cited by Foods & Nutrition
In vitro · 2019
Anti-Inflammatory Action of Blueberry Polyphenols in HIG-82 Rabbit Synoviocytes
South S et al. · Journal of Medicinal Food · cited by Foods & Nutrition
Meta-analysis · 2019
Efficacy and safety of avocado-soybean unsaponifiables for the treatment of hip and knee osteoarthritis: A systematic review and meta-analysis of randomized placebo-controlled trials
Simental-Mendía M et al. · International Journal of Rheumatic Diseases · cited by Supplements
In vitro · 2019
Bone Broth Unlikely to Provide Reliable Concentrations of Collagen Precursors Compared With Supplemental Sources of Collagen Used in Collagen Research
Alcock RD et al. · International Journal of Sport Nutrition and Exercise Metabolism · cited by Foods & Nutrition
RCT · 2019 · n=10
Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis
Lis DM et al. · International Journal of Sport Nutrition and Exercise Metabolism · cited by Foods & Nutrition and Supplements
RCT · 2019 · n=15
Plasma Amino Acid Concentrations After the Ingestion of Dairy and Collagen Proteins, in Healthy Active Males
Alcock RD et al. · Frontiers in Nutrition · cited by Foods & Nutrition
Cohort · 2019 · n=4,330
Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study
Veronese N et al. · Clinical Nutrition · cited by Foods & Nutrition
In vitro · 2019
Chicken leg bone as a source of chondroitin sulfate
Wang X et al. · Carbohydrate Polymers · cited by Foods & Nutrition
In vitro · 2019
Biotechnological Preparation of Gelatines from Chicken Feet
Mokrejš P et al. · Polymers · cited by Foods & Nutrition
Cohort · 2019 · n=341
The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV
Adrian S et al. · The Journal of Frailty & Aging · cited by Peptides
RCT · 2019 · n=192
Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial
Di Martino A et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2019 · n=16
Intra-articular injection of autologous adipose-derived stromal vascular fractions for knee osteoarthritis: a double-blind randomized self-controlled trial
Hong Z et al. · International Orthopaedics · cited by Injections
RCT · 2019 · n=24
Intra-Articular Injection of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase IIb, Randomized, Placebo-Controlled Clinical Trial
Lee WS et al. · Stem Cells Translational Medicine · cited by Injections
RCT · 2019 · n=30
Adipose-derived mesenchymal stem cell therapy in the treatment of knee osteoarthritis: a randomized controlled trial
Freitag J et al. · Regenerative Medicine · cited by Injections
RCT · 2019 · n=26
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
Matas J et al. · Stem Cells Translational Medicine · cited by Injections
Case series · 2019 · n=12
Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation
Chahal J et al. · Stem Cells Translational Medicine · cited by Injections
Cohort · 2019 · n=684
Intra-articular corticosteroids and the risk of knee osteoarthritis progression: results from the Osteoarthritis Initiative
Zeng C et al. · Osteoarthritis and Cartilage · cited by Injections
Review · 2019
Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought?
Kompel AJ et al. · Radiology · cited by Injections
Cohort · 2019 · n=29
The Plasma NAD(+) Metabolome Is Dysregulated in "Normal" Aging
Clement J et al. · Rejuvenation Research · cited by Supplements
In vitro · 2019
NAD(+) metabolism governs the proinflammatory senescence-associated secretome
Nacarelli T et al. · Nature Cell Biology · cited by Supplements
In vitro · 2019
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD(+) decline
Chini C et al. · Biochemical and Biophysical Research Communications · cited by Supplements
Animal · 2019
Slc12a8 is a nicotinamide mononucleotide transporter
Grozio A et al. · Nature Metabolism · cited by Supplements
Review · 2019
Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter
Schmidt MS et al. · Nature Metabolism · cited by Supplements
Review · 2019
Reply to: Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter
Grozio A et al. · Nature Metabolism · cited by Supplements
RCT · 2019 · n=140
Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Conze D et al. · Scientific Reports · cited by Supplements
RCT · 2019 · n=12
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Elhassan YS et al. · Cell Reports · cited by Supplements
Case series · 2019 · n=2
The biomechanical role of meniscal allograft transplantation and preliminary in-vivo kinematic evaluation
Zaffagnini S et al. · Journal of Experimental Orthopaedics · cited by Treatments & Surgery
Review · 2019
Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing
Gwyer D et al. · Cell and Tissue Research · cited by Peptides
Case series · 2019 · n=35
Phenotypic Spectrum of Pentosan Polysulfate Sodium-Associated Maculopathy: A Multicenter Study
Hanif AM et al. · JAMA Ophthalmology · cited by Peptides
Meta-analysis · 2019
Efficacy of pentosan polysulfate for the treatment of interstitial cystitis/bladder pain syndrome: results of a systematic review of randomized controlled trials
van Ophoven A et al. · Current Medical Research and Opinion · cited by Peptides
In vitro · 2019
Human osteocyte expression of Nerve Growth Factor: The effect of Pentosan Polysulphate Sodium (PPS) and implications for pain associated with knee osteoarthritis
Stapledon CJM et al. · PLoS One · cited by Peptides
Meta-analysis · 2019
Fluoroquinolones and the risk of tendon injury: a systematic review and meta-analysis
Alves C et al. · European Journal of Clinical Pharmacology · cited by Precautions
Cohort · 2019 · n=186
The effect of extracorporeal shock wave therapy on the treatment of moderate to severe knee osteoarthritis and cartilage lesion
Xu Y et al. · Medicine · cited by Light, Heat & Devices
Animal · 2019 · n=40
Shockwave Targeting on Subchondral Bone Is More Suitable than Articular Cartilage for Knee Osteoarthritis
Chou WY et al. · International Journal of Medical Sciences · cited by Light, Heat & Devices
Review · 2019
OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
Bannuru RR et al. · Osteoarthritis and Cartilage · cited by Supplements
RCT · 2019 · n=150
Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study
Henrotin Y et al. · Arthritis Research & Therapy · cited by Supplements
RCT · 2019 · n=139
Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study
Shep D et al. · Trials · cited by Supplements
Animal · 2019
Involvement of TLR4 in the protective effect of intra-articular administration of curcumin on rat experimental osteoarthritis
Yan D et al. · Acta Cirurgica Brasileira · cited by Supplements
Meta-analysis · 2019 · n=1,344
Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials
White CM et al. · Pharmacological Research · cited by Supplements
RCT · 2019
Oral Bioavailability and Pharmacokinetics of Nonanimal Chondroitin Sulfate and Its Constituents in Healthy Male Volunteers
Volpi N et al. · Clinical Pharmacology in Drug Development · cited by Foods & Nutrition and Supplements
Meta-analysis · 2019 · n=195
Effect of Betaine on Reducing Body Fat-A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Gao X et al. · Nutrients · cited by Supplements
RCT · 2019 · n=68
The effect of menaquinone-7 supplementation on vascular calcification in patients with diabetes: a randomized, double-blind, placebo-controlled trial
Zwakenberg SR et al. · The American Journal of Clinical Nutrition · cited by Supplements
Meta-analysis · 2019 · n=8,882
The efficacy and safety of menatetrenone in the management of osteoporosis: a systematic review and meta-analysis of randomized controlled trials
Su S et al. · Osteoporosis International · cited by Supplements
Review · 2018
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes
Jahanban-Esfahlan R et al. · Br J Pharmacol · cited by Peptides
Review · 2018
BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing
Seiwerth S et al. · Current Pharmaceutical Design · cited by Peptides
In vitro · 2018
Comparative Analysis of Peptide Composition and Bioactivity of Different Collagen Hydrolysate Batches on Human Osteoarthritic Synoviocytes
Simons VS et al. · Scientific Reports · cited by Supplements
Meta-analysis · 2018
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis
Liu X et al. · British Journal of Sports Medicine · cited by Supplements
RCT · 2018 · n=131
Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study
König D et al. · Nutrients · cited by Supplements
RCT · 2018 · n=50
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Dressler P et al. · Journal of Sports Science & Medicine · cited by Supplements
Animal · 2018 · n=38
Specific bioactive collagen peptides (PETAGILE) as supplement for horses with osteoarthritis: A two-centred study
Dobenecker B et al. · Journal of Animal Physiology and Animal Nutrition · cited by Supplements
Case series · 2018
Changes in composition and content of food-derived peptide in human blood after daily ingestion of collagen hydrolysate for 4 weeks
Shigemura Y et al. · Journal of the Science of Food and Agriculture · cited by Supplements
RCT · 2018 · n=48
Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis
Ferraz RB et al. · Medicine and Science in Sports and Exercise · cited by Exercise & Rehab
Review · 2018
What is the evidence for a role for diet and nutrition in osteoarthritis?
Thomas S et al. · Rheumatology (Oxford) · cited by Foods & Nutrition
Cohort · 2018 · n=1,133
Association of Vitamin K Status Combined With Vitamin D Status and Lower-Extremity Function: A Prospective Analysis of Two Knee Osteoarthritis Cohorts
Shea MK et al. · Arthritis Care & Research (Hoboken) · cited by Foods & Nutrition
Meta-analysis · 2018 · n=2,931
Effects of five types of selenium supplementation for treatment of Kashin-Beck disease in children: a systematic review and network meta-analysis
Xie D et al. · BMJ Open · cited by Foods & Nutrition
Cohort · 2018
Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative
Shmagel A et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
In vitro · 2018
Cyanidin suppresses autophagic activity regulating chondrocyte hypertrophic differentiation
Cao Z et al. · Journal of Cellular Physiology · cited by Foods & Nutrition
Cohort · 2018 · n=94
The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two urolithin-metabotypes that correlate with cardiometabolic risk biomarkers: Comparison between normoweight, overweight-obesity and metabolic syndrome
Selma MV et al. · Clinical Nutrition · cited by Foods & Nutrition
Review · 2018
Dietary fruits and arthritis
Basu A et al. · Food & Function · cited by Foods & Nutrition
In vitro · 2018
Identifying chondroprotective diet-derived bioactives and investigating their synergism
Davidson RK et al. · Scientific Reports · cited by Foods & Nutrition
RCT · 2018 · n=18
Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of BMI and daily consumption in a randomised clinical trial
Charron CS et al. · The British Journal of Nutrition · cited by Foods & Nutrition
RCT · 2018 · n=50
Green tea (Camellia sinensis) for patients with knee osteoarthritis: A randomized open-label active-controlled clinical trial
Hashempur MH et al. · Clinical Nutrition · cited by Foods & Nutrition
RCT · 2018 · n=17
Strawberries decrease circulating levels of tumor necrosis factor and lipid peroxides in obese adults with knee osteoarthritis
Basu A et al. · Food & Function · cited by Foods & Nutrition
Animal · 2018
Dose-Related Antihypertensive Properties and the Corresponding Mechanisms of a Chicken Foot Hydrolysate in Hypertensive Rats
Mas-Capdevila A et al. · Nutrients · cited by Foods & Nutrition
In vitro · 2018
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
de Paz-Lugo P et al. · Amino Acids · cited by Foods & Nutrition
Cohort · 2018 · n=783
The association between the Mediterranean diet and magnetic resonance parameters for knee osteoarthritis: data from the Osteoarthritis Initiative
Veronese N et al. · Clinical Rheumatology · cited by Foods & Nutrition
In vitro · 2018
The ghrelin paradox in the control of equine chondrocyte function: The good and the bad
Ceriotti S et al. · Peptides · cited by Peptides
Cohort · 2018 · n=2,084
Sauna bathing and systemic inflammation
Laukkanen JA et al. · European Journal of Epidemiology · cited by Light, Heat & Devices
Review · 2018
Cardiovascular and Other Health Benefits of Sauna Bathing: A Review of the Evidence
Laukkanen JA et al. · Mayo Clinic Proceedings · cited by Light, Heat & Devices
RCT · 2018 · n=30
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II)
Lamo-Espinosa JM et al. · Journal of Translational Medicine · cited by Injections
Animal · 2018
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD(+) Decline
Tarragó MG et al. · Cell Metabolism · cited by Supplements
RCT · 2018 · n=30
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults
Martens CR et al. · Nature Communications · cited by Supplements
RCT · 2018 · n=128
Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Five-Year Follow-up of a Prospective Randomized Trial
Brittberg M et al. · The American Journal of Sports Medicine · cited by Exercise & Rehab and Treatments & Surgery
RCT · 2018 · n=146
Arthroscopic partial meniscectomy versus placebo surgery for a degenerative meniscus tear: a 2-year follow-up of the randomised controlled trial
Sihvonen R et al. · Annals of the Rheumatic Diseases · cited by Treatments & Surgery
Case series · 2018 · n=6
Pigmentary Maculopathy Associated with Chronic Exposure to Pentosan Polysulfate Sodium
Pearce WA et al. · Ophthalmology · cited by Peptides
In vitro · 2018
Mitochondrial dysfunction is an acute response of articular chondrocytes to mechanical injury
Delco ML et al. · Journal of Orthopaedic Research · cited by Peptides
In vitro · 2018
Mitoprotective therapy preserves chondrocyte viability and prevents cartilage degeneration in an ex vivo model of posttraumatic osteoarthritis
Delco ML et al. · Journal of Orthopaedic Research · cited by Peptides
RCT · 2018 · n=109
Sodium pentosan polysulfate efficacy as thromboprophylaxis agent in high-risk women following gynecological surgery
Indirayani I et al. · The Journal of Obstetrics and Gynaecology Research · cited by Peptides
RCT · 2018 · n=201
Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study
Haroyan A et al. · BMC Complementary and Alternative Medicine · cited by Supplements
RCT · 2018 · n=50
A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene versus Placebo in Reducing Symptoms of Knee OA
Panda SK et al. · BioMed Research International · cited by Supplements
Meta-analysis · 2018 · n=1,009
Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
Bannuru RR et al. · Seminars in Arthritis and Rheumatism · cited by Supplements
RCT · 2018 · n=12
Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects
Purpura M et al. · European Journal of Nutrition · cited by Supplements
RCT · 2018 · n=60
Beneficial effects of natural eggshell membrane versus placebo in exercise-induced joint pain, stiffness, and cartilage turnover in healthy, postmenopausal women
Ruff KJ et al. · Clinical Interventions in Aging · cited by Supplements
RCT · 2018 · n=110
Efficacy and safety of co-administration of resveratrol with meloxicam in patients with knee osteoarthritis: a pilot interventional study
Hussain SA et al. · Clinical Interventions in Aging · cited by Supplements
RCT · 2018 · n=110
Resveratrol Supplementation Reduces Pain and Inflammation in Knee Osteoarthritis Patients Treated with Meloxicam: A Randomized Placebo-Controlled Study
Marouf BH et al. · Journal of Medicinal Food · cited by Supplements
Animal · 2018
Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration
Song Y et al. · Redox Biology · cited by Supplements
RCT · 2018 · n=23
The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial
Cholewa JM et al. · Journal of the International Society of Sports Nutrition · cited by Supplements
Animal · 2018 · n=12
Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis
Ma CH et al. · Redox Biology · cited by Supplements
Case series · 2018 · n=50
Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation: Two-Year Follow-up
López-Alcorocho JM et al. · Cartilage · cited by Treatments & Surgery
Systematic review · 2018 · n=1,036
Clinical Outcomes and Failure Rates of Osteochondral Allograft Transplantation in the Knee: A Systematic Review
Familiari F et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
Animal · 2018
No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart
Weinberger F et al. · Pharmacology Research & Perspectives · cited by Peptides
RCT · 2018 · n=601
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-2
ReGenTree, LLC · ClinicalTrials.gov registration with posted results · cited by Peptides
In vitro · 2017
Identification of Peptide AEDG in the Polypeptide Complex of the Pineal Gland
Khavinson VK et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
Review · 2017
Cellular senescence in osteoarthritis pathology
McCulloch K et al. · Aging Cell · cited by Peptides
In vitro · 2017
Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation
Hsieh MJ et al. · Journal of Molecular Medicine · cited by Peptides
Animal · 2017
Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME
Drmic D et al. · World Journal of Gastroenterology · cited by Peptides
In vitro · 2017
Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H
Cox HD et al. · Drug Testing and Analysis · cited by Peptides
RCT · 2017 · n=160
Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides
Zdzieblik D et al. · Applied Physiology, Nutrition, and Metabolism · cited by Supplements
RCT · 2017 · n=8
Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis
Shaw G et al. · The American Journal of Clinical Nutrition · cited by Foods & Nutrition and Supplements
Case series · 2017 · n=25
Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails
Hexsel D et al. · Journal of Cosmetic Dermatology · cited by Supplements
Meta-analysis · 2017 · n=114,829
Running and Knee Osteoarthritis: A Systematic Review and Meta-analysis
Timmins KA et al. · The American Journal of Sports Medicine · cited by Exercise & Rehab
Case series · 2017 · n=23
The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1 rho and T2 mapping
Chen M et al. · PLoS One · cited by Exercise & Rehab
Cohort · 2017 · n=5,022
Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts
Dai Z et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition
Cohort · 2017 · n=4,470
Dietary Fiber Intake in Relation to Knee Pain Trajectory
Dai Z et al. · Arthritis Care & Research (Hoboken) · cited by Foods & Nutrition
Animal · 2017 · n=27
Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis
Akhtar N et al. · Nutrition · cited by Foods & Nutrition
In vitro · 2017
A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-κB and IL-6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes
Haseeb A et al. · Phytotherapy Research · cited by Foods & Nutrition
Review · 2017
Urolithins, the rescue of "old" metabolites to understand a "new" concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status
Tomás-Barberán FA et al. · Molecular Nutrition & Food Research · cited by Foods & Nutrition
RCT · 2017 · n=40
Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint
Davidson R et al. · Scientific Reports · cited by Foods & Nutrition
Animal · 2017 · n=16
Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis
Javaheri B et al. · Bone · cited by Foods & Nutrition
In vitro · 2017
Sulforaphane formation and bioaccessibility are more affected by steaming time than meal composition during in vitro digestion of broccoli
Sarvan I et al. · Food Chemistry · cited by Foods & Nutrition
Review · 2017
Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside
Chin KY et al. · Nutrients · cited by Foods & Nutrition
RCT · 2017 · n=17
Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis
Schell J et al. · Nutrients · cited by Foods & Nutrition
Animal · 2017
Elucidating the Role of Protandim and 6-Gingerol in Protection Against Osteoarthritis
Abusarah J et al. · Journal of Cellular Biochemistry · cited by Supplements
In vitro · 2017
Essential and toxic metals in animal bone broths
Hsu DJ et al. · Food & Nutrition Research · cited by Foods & Nutrition
Meta-analysis · 2017 · n=2,751
Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials
Senftleber NK et al. · Nutrients · cited by Foods & Nutrition
RCT · 2017 · n=99
Effect of a Mediterranean Type Diet on Inflammatory and Cartilage Degradation Biomarkers in Patients with Osteoarthritis
Dyer J et al. · The Journal of Nutrition, Health & Aging · cited by Foods & Nutrition
Cohort · 2017 · n=640
Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative
Gersing AS et al. · Radiology · cited by Foods & Nutrition
In vitro · 2017
Effects of Hot-Pressure Extraction Time on Composition and Gelatin Properties of Chicken Bone Extracts
Yue JY et al. · Journal of Food Science · cited by Foods & Nutrition
Animal · 2017
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis
Wang X et al. · Wound Repair and Regeneration · cited by Peptides
RCT · 2017 · n=162
Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled trial
Görmeli G et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Injections
RCT · 2017 · n=25
A Prospective, Single-Blind, Placebo-Controlled Trial of Bone Marrow Aspirate Concentrate for Knee Osteoarthritis
Shapiro SA et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2017 · n=140
Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial
McAlindon TE et al. · JAMA · cited by Injections
RCT · 2017 · n=98
Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study
Lopes de Jesus CC et al. · PLoS One · cited by Injections
RCT · 2017 · n=74
No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial
Kjær TN et al. · The Journal of Clinical Endocrinology and Metabolism · cited by Supplements
Cohort · 2017 · n=355
Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year
Roemer FW et al. · European Radiology · cited by Treatments & Surgery
Meta-analysis · 2017 · n=345
Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome
Martimbianco ALC et al. · Cochrane Database of Systematic Reviews · cited by Light, Heat & Devices
Case report · 2017 · n=1
Improved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment
Sampson MJ et al. · BMC Musculoskeletal Disorders · cited by Peptides
In vitro · 2017
Pentosan polysulfate inhibits IL-1β-induced iNOS, c-Jun and HIF-1α upregulation in canine articular chondrocytes
Bwalya EC et al. · PLoS One · cited by Peptides
Meta-analysis · 2017 · n=125,810
The Association of Recreational and Competitive Running With Hip and Knee Osteoarthritis: A Systematic Review and Meta-analysis
Alentorn-Geli E et al. · Journal of Orthopaedic and Sports Physical Therapy · cited by Exercise & Rehab and Precautions
Animal · 2017 · n=48
Changes of articular cartilage and subchondral bone after extracorporeal shockwave therapy in osteoarthritis of the knee
Wang CJ et al. · International Journal of Medical Sciences · cited by Light, Heat & Devices
Animal · 2017 · n=56
Medial tibial subchondral bone is the key target for extracorporeal shockwave therapy in early osteoarthritis of the knee
Wang CJ et al. · American Journal of Translational Research · cited by Light, Heat & Devices
Meta-analysis · 2017 · n=1,625
Subgroup analyses of the effectiveness of oral glucosamine for knee and hip osteoarthritis: a systematic review and individual patient data meta-analysis from the OA trial bank
Runhaar J et al. · Annals of the Rheumatic Diseases · cited by Supplements
RCT · 2017 · n=164
Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impairment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Roman-Blas JA et al. · Arthritis & Rheumatology · cited by Supplements
Review · 2017
Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
Butawan M et al. · Nutrients · cited by Foods & Nutrition and Supplements
RCT · 2017 · n=12
Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers
Asher GN et al. · Journal of Clinical Pharmacology · cited by Supplements
Review · 2017
The Essential Medicinal Chemistry of Curcumin
Nelson KM et al. · Journal of Medicinal Chemistry · cited by Supplements
Cohort · 2017 · n=340
Maintaining Vitamin D Sufficiency Is Associated with Improved Structural and Symptomatic Outcomes in Knee Osteoarthritis
Zheng S et al. · The American Journal of Medicine · cited by Supplements
Meta-analysis · 2017 · n=1,136
The effect of vitamin D supplementation on knee osteoarthritis: A meta-analysis of randomized controlled trials
Gao XR et al. · International Journal of Surgery · cited by Supplements
Meta-analysis · 2017 · n=721
Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis
Chilibeck PD et al. · Open Access Journal of Sports Medicine · cited by Supplements
Review · 2017
International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine
Kreider RB et al. · Journal of the International Society of Sports Nutrition · cited by Supplements
Review · 2017
Zinc: the Other Suspected Environmental Factor in Kashin-Beck Disease in Addition to Selenium
Wang X et al. · Biological Trace Element Research · cited by Supplements
Case series · 2017 · n=31
A Prospective Clinical and Radiological Evaluation at 5 Years After Arthroscopic Matrix-Induced Autologous Chondrocyte Implantation
Ebert JR et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
Systematic review · 2017 · n=578
Matrix-Assisted Autologous Chondrocyte Transplantation in the Knee: A Systematic Review of Mid- to Long-Term Clinical Outcomes
Schuette HB et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
Cohort · 2017 · n=143
Increased Expression of Thymosin β4 Is Independently Correlated with Hypoxia Inducible Factor-1α (HIF-1α) and Worse Clinical Outcome in Human Colorectal Cancer
Lee SY et al. · Journal of Pathology and Translational Medicine · cited by Peptides
Animal · 2016
[OPTIMIZATION OF REPARATIVE OSTEOGENESIS JAWS ON AGING (PRECLINICAL STUDIES)]
Slugina AS et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Review · 2016
Cellular senescence in aging and osteoarthritis
Toh WS et al. · Acta Orthop · cited by Peptides
Cohort · 2016 · n=775
Specific premature epigenetic aging of cartilage in osteoarthritis
Vidal-Bralo L et al. · Aging (Albany NY) · cited by Peptides
RCT · 2016 · n=30
Determination of serum biomarkers in osteoarthritis patients: a previous interventional imaging study revisited
McAlindon T et al. · Journal of Biomedical Research · cited by Supplements
Cohort · 2016 · n=197,271
Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones
Ferraro PM et al. · American Journal of Kidney Diseases · cited by Supplements
RCT · 2016 · n=48
Improved Function and Reduced Pain after Swimming and Cycling Training in Patients with Osteoarthritis
Alkatan M et al. · The Journal of Rheumatology · cited by Exercise & Rehab
Systematic review · 2016 · n=13
Aquatic exercise for the treatment of knee and hip osteoarthritis
Bartels EM et al. · Cochrane Database of Systematic Reviews · cited by Exercise & Rehab
Systematic review · 2016 · n=1,117
Return to Sport After Articular Cartilage Repair in Athletes' Knees: A Systematic Review
Campbell AB et al. · Arthroscopy · cited by Exercise & Rehab
Case series · 2016
In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee
Chan DD et al. · Scientific Reports · cited by Exercise & Rehab
Cohort · 2016 · n=5,764
Relationship between soy milk intake and radiographic knee joint space narrowing and osteophytes
Li H et al. · Rheumatology International · cited by Foods & Nutrition
Review · 2016
The Role of Vitamin K in Chronic Aging Diseases: Inflammation, Cardiovascular Disease, and Osteoarthritis
Harshman SG et al. · Current Nutrition Reports · cited by Foods & Nutrition
Meta-analysis · 2016 · n=2,652
Salt-Rich Selenium for Prevention and Control Children with Kashin-Beck Disease: a Meta-analysis of Community-Based Trial
Yu FF et al. · Biological Trace Element Research · cited by Foods & Nutrition
Meta-analysis · 2016
The effects of T-2 toxin on the prevalence and development of Kashin-Beck disease in China: a meta-analysis and systematic review
Li D et al. · Toxicology Research · cited by Foods & Nutrition
RCT · 2016 · n=202
Supplementation with omega-3 fish oil has no effect on bone mineral density in adults with knee osteoarthritis: a 2-year randomized controlled trial
Chen JS et al. · Osteoporosis International · cited by Foods & Nutrition
RCT · 2016 · n=38
The effect of pomegranate juice on clinical signs, matrix metalloproteinases and antioxidant status in patients with knee osteoarthritis
Ghoochani N et al. · Journal of the Science of Food and Agriculture · cited by Foods & Nutrition
Cohort · 2016 · n=214
Association Between Dietary Intake of Antioxidants and Prevalence of Femoral Head Cartilage Defects and Bone Marrow Lesions in Community-based Adults
Wang Y et al. · The Journal of Rheumatology · cited by Foods & Nutrition
RCT · 2016 · n=120
Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial
Mozaffari-Khosravi H et al. · Journal of Nutrition in Gerontology and Geriatrics · cited by Supplements
RCT · 2016 · n=202
Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose
Hill CL et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition
Cohort · 2016 · n=4,470
Adherence to the Mediterranean diet is associated with better quality of life: data from the Osteoarthritis Initiative
Veronese N et al. · The American Journal of Clinical Nutrition · cited by Foods & Nutrition
Cohort · 2016 · n=1,383
Is There a Dose-Response Relationship Between Weight Loss and Symptom Improvement in Persons With Knee Osteoarthritis?
Atukorala I et al. · Arthritis Care & Research · cited by Foods & Nutrition
RCT · 2016 · n=45
Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth
Lee WJ et al. · Annals of Dermatology · cited by Peptides
Case report · 2016 · n=1
Significant improvement in crow's feet after treatment with Jet-M and a mixed solution of copper-GHK, oligo-hyaluronic acid, rhodiolar extract, tranexamic acid, and β-glucan (GHR formulation)
Byun SY et al. · Journal of Cosmetic and Laser Therapy · cited by Peptides
Animal · 2016
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Park JR et al. · Oncotarget · cited by Peptides
In vitro · 2016
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
Li H et al. · Scientific Reports · cited by Peptides
RCT · 2016 · n=20
Passive heat therapy improves endothelial function, arterial stiffness and blood pressure in sedentary humans
Brunt VE et al. · The Journal of Physiology · cited by Light, Heat & Devices
Meta-analysis · 2016 · n=1,055
Effect of Leukocyte Concentration on the Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis
Riboh JC et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2016 · n=30
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
Lamo-Espinosa JM et al. · Journal of Translational Medicine · cited by Injections
Review · 2016
Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee
Altman RD et al. · The American Journal of Sports Medicine · cited by Injections
Animal · 2016
Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
Mills KF et al. · Cell Metabolism · cited by Supplements
RCT · 2016 · n=140
Exercise therapy versus arthroscopic partial meniscectomy for degenerative meniscal tear in middle aged patients: randomised controlled trial with two year follow-up
Kise NJ et al. · BMJ · cited by Treatments & Surgery
Review · 2016
Posterior meniscal root injuries
Moatshe G et al. · Acta Orthopaedica · cited by Treatments & Surgery
In vitro · 2016
Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro
Lin'kova NS et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
Animal · 2016
Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs
Simonaro CM et al. · PLoS One · cited by Peptides
Review · 2016
The training-injury prevention paradox: should athletes be training smarter and harder?
Gabbett TJ · British Journal of Sports Medicine · cited by Exercise & Rehab and Precautions
Meta-analysis · 2016 · n=50,000
Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation
Irwin MR et al. · Biological Psychiatry · cited by Precautions
RCT · 2016 · n=606
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Hochberg MC et al. · Annals of the Rheumatic Diseases · cited by Supplements
Meta-analysis · 2016 · n=937
Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Daily JW et al. · Journal of Medicinal Food · cited by Supplements
RCT · 2016 · n=40
Mitigation of Systemic Oxidative Stress by Curcuminoids in Osteoarthritis: Results of a Randomized Controlled Trial
Panahi Y et al. · Journal of Dietary Supplements · cited by Supplements
Meta-analysis · 2016
The Role of Curcumin Administration in Patients with Major Depressive Disorder: Mini Meta-Analysis of Clinical Trials
Al-Karawi D et al. · Phytotherapy Research · cited by Supplements
RCT · 2016 · n=191
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
Lugo JP et al. · Nutrition Journal · cited by Foods & Nutrition and Supplements
Review · 2016
Oral hyaluronan relieves knee pain: a review
Oe M et al. · Nutrition Journal · cited by Supplements
Animal · 2016
Absorption of Orally Administered Hyaluronan
Kimura M et al. · Journal of Medicinal Food · cited by Foods & Nutrition and Supplements
RCT · 2016 · n=39
Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial
Bakilan F et al. · Eurasian Journal of Medicine · cited by Supplements
RCT · 2016 · n=413
Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial
Jin X et al. · JAMA · cited by Supplements
RCT · 2016 · n=474
The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial
Arden NK et al. · Osteoarthritis and Cartilage · cited by Supplements
Animal · 2016
Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis
Fu Y et al. · Arthritis & Rheumatology · cited by Supplements
Animal · 2016
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism
Camacho-Pereira J et al. · Cell Metabolism · cited by Supplements
RCT · 2016 · n=40
Can Creatine Supplementation Improve Body Composition and Objective Physical Function in Rheumatoid Arthritis Patients? A Randomized Controlled Trial
Wilkinson TJ et al. · Arthritis Care & Research · cited by Supplements
Animal · 2016
Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis
Won Y et al. · Annals of the Rheumatic Diseases · cited by Supplements
Review · 2016
Concepts and Controversies in Evaluating Vitamin K Status in Population-Based Studies
Shea MK et al. · Nutrients · cited by Supplements
In vitro · 2016
Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis
Cavaco S et al. · Cellular and Molecular Life Sciences · cited by Supplements
Systematic review · 2016 · n=1,726
Knee donor-site morbidity after mosaicplasty - a systematic review
Andrade R et al. · Journal of Experimental Orthopaedics · cited by Treatments & Surgery
Systematic review · 2016 · n=610
Long-term Outcomes After Osteochondral Autograft Transfer: A Systematic Review at Mean Follow-up of 10.2 Years
Pareek A et al. · Arthroscopy · cited by Treatments & Surgery
RCT · 2016 · n=80
A Randomized Multicenter Trial Comparing Autologous Chondrocyte Implantation with Microfracture: Long-Term Follow-up at 14 to 15 Years
Knutsen G et al. · The Journal of Bone and Joint Surgery. American Volume · cited by Treatments & Surgery
Systematic review · 2016 · n=1,189
Return to Work and Sport Following High Tibial Osteotomy: A Systematic Review
Ekhtiari S et al. · The Journal of Bone and Joint Surgery. American Volume · cited by Treatments & Surgery
In vitro · 2016 · n=50
The TMSB4 Pseudogene LncRNA Functions as a Competing Endogenous RNA to Promote Cartilage Degradation in Human Osteoarthritis
Liu Q et al. · Molecular Therapy · cited by Peptides
In vitro · 2016
Thymosin β4 induces proliferation, invasion, and epithelial-to-mesenchymal transition of oral squamous cell carcinoma
Hong KO et al. · Amino Acids · cited by Peptides
Animal · 2015 · n=32
Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model
Kwon DR et al. · Annals of Clinical and Laboratory Science · cited by Peptides
In vitro · 2015
[POLYPEPTIDES INFLUENCE ON TISSUE CELL CULTURES REGENERATION OF VARIOUS AGE RATS]
Ryzhak AP et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Review · 2015
Osteoarthritis and telomere shortening
Kuszel L et al. · J Appl Genet · cited by Peptides
Animal · 2015
Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro
Huang T et al. · Drug Design, Development and Therapy · cited by Peptides
Registry · 2015 · n=42
Phase I, Pilot Study in Healthy Volunteers, to Assess the Safety and Pharmacokinetics of PCO-02, Which Active Ingredient is BPC-157, a Penta-deca-peptide From Gastric Source
PharmaCotherapia d.o.o. · ClinicalTrials.gov registration · cited by Peptides
RCT · 2015
A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis
Kumar S et al. · Journal of the Science of Food and Agriculture · cited by Supplements
RCT · 2015 · n=53
Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial
Zdzieblik D et al. · British Journal of Nutrition · cited by Supplements
RCT · 2015 · n=105
Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology
Schunck M et al. · Journal of Medicinal Food · cited by Supplements
Cohort · 2015 · n=210
Accuracy of cartilage-specific 3-Tesla 3D-DESS magnetic resonance imaging in the diagnosis of chondral lesions: comparison with knee arthroscopy
Kohl S et al. · Journal of Orthopaedic Surgery and Research · cited by 1 page
Systematic review · 2015 · n=54
Exercise for osteoarthritis of the knee
Fransen M et al. · Cochrane Database of Systematic Reviews · cited by Exercise & Rehab
RCT · 2015 · n=40
Efficacy of blood flow-restricted, low-load resistance training in women with risk factors for symptomatic knee osteoarthritis
Segal NA et al. · PM&R · cited by Exercise & Rehab
RCT · 2015 · n=249
Randomized Multicenter Placebo-Controlled Trial of Omega-3 Fatty Acids for the Control of Aromatase Inhibitor-Induced Musculoskeletal Pain: SWOG S0927
Hershman DL et al. · Journal of Clinical Oncology · cited by Foods & Nutrition
Cohort · 2015 · n=1,626
Association between Dietary Magnesium Intake and Radiographic Knee Osteoarthritis
Zeng C et al. · PLoS One · cited by Foods & Nutrition
Review · 2015
Nothing Boring About Boron
Pizzorno L · Integrative Medicine (Encinitas) · cited by Foods & Nutrition
Animal · 2015 · n=42
Intra-Articular Injections of Polyphenols Protect Articular Cartilage from Inflammation-Induced Degradation: Suggesting a Potential Role in Cartilage Therapeutics
Natarajan V et al. · PLoS One · cited by Foods & Nutrition
Meta-analysis · 2015 · n=593
Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials
Bartels EM et al. · Osteoarthritis and Cartilage · cited by Supplements
Review · 2015
Management of Osteoarthritis with Avocado/Soybean Unsaponifiables
Christiansen BA et al. · Cartilage · cited by Supplements
Cohort · 2015 · n=2,315
Association between sauna bathing and fatal cardiovascular and all-cause mortality events
Laukkanen T et al. · JAMA Internal Medicine · cited by Light, Heat & Devices
RCT · 2015 · n=10
Effects of far-infrared sauna bathing on recovery from strength and endurance training sessions in men
Mero A et al. · SpringerPlus · cited by Light, Heat & Devices
RCT · 2015 · n=192
Platelet-Rich Plasma Intra-articular Knee Injections Show No Superiority Versus Viscosupplementation: A Randomized Controlled Trial
Filardo G et al. · The American Journal of Sports Medicine · cited by Injections
RCT · 2015 · n=30
Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial
Vega A et al. · Transplantation · cited by Injections
Meta-analysis · 2015 · n=33,243
Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis
Bannuru RR et al. · Annals of Internal Medicine · cited by Injections
Meta-analysis · 2015 · n=1,767
Intra-articular corticosteroid for knee osteoarthritis
Jüni P et al. · The Cochrane Database of Systematic Reviews · cited by Injections
Cohort · 2015 · n=17
In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences
Zhu XH et al. · Proceedings of the National Academy of Sciences · cited by Supplements
In vitro · 2015
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Cao D et al. · Genes & Development · cited by Supplements
RCT · 2015 · n=119
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
Turner RS et al. · Neurology · cited by Supplements
Review · 2015
The Meniscus-Deficient Knee: Biomechanics, Evaluation, and Treatment Options
Rao AJ et al. · Orthopaedic Journal of Sports Medicine · cited by Treatments & Surgery
Meta-analysis · 2015 · n=9
Arthroscopic surgery for degenerative knee: systematic review and meta-analysis of benefits and harms
Thorlund JB et al. · BMJ · cited by Treatments & Surgery
Animal · 2015
Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction
Fu SC et al. · Journal of Orthopaedic Research · cited by Peptides
Review · 2015
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Pickart L et al. · BioMed Research International · cited by Peptides
Review · 2015
Advances in the basic and clinical applications of thymosin β4
Goldstein AL et al. · Expert Opinion on Biological Therapy · cited by Peptides
RCT · 2015 · n=368
Pentosan polysulfate sodium for treatment of interstitial cystitis/bladder pain syndrome: insights from a randomized, double-blind, placebo controlled study
Nickel JC et al. · The Journal of Urology · cited by Peptides
Cohort · 2015 · n=1,846
Effects of prescription nonsteroidal antiinflammatory drugs on symptoms and disease progression among patients with knee osteoarthritis
Lapane KL et al. · Arthritis & Rheumatology · cited by Precautions
Cohort · 2015 · n=208
Sleep, Pain Catastrophizing, and Central Sensitization in Knee Osteoarthritis Patients With and Without Insomnia
Campbell CM et al. · Arthritis Care & Research · cited by Precautions
RCT · 2015 · n=40
Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial
Rahimnia AR et al. · Drug Research · cited by Supplements
In vitro · 2015
Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer
Comblain F et al. · PLoS One · cited by Supplements
Systematic review · 2015 · n=9,110
Chondroitin for osteoarthritis
Singh JA et al. · Cochrane Database of Systematic Reviews · cited by Foods & Nutrition and Supplements
Animal · 2015
Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α
Li W et al. · Journal of Orthopaedic Research · cited by Supplements
Cohort · 2015 · n=523
The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study
Shea MK et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition and Supplements
RCT · 2015 · n=244
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial
Knapen MH et al. · Thrombosis and Haemostasis · cited by Supplements
RCT · 2015 · n=9
Thymosin β4 significantly improves signs and symptoms of severe dry eye in a phase 2 randomized trial
Sosne G et al. · Cornea · cited by Peptides
RCT · 2015 · n=72
Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial conducted using the controlled adverse environment (CAE) model
Sosne G et al. · Clinical Ophthalmology · cited by Peptides
In vitro · 2015
Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence
Wang YY et al. · Chinese Medical Journal · cited by Peptides
Animal · 2014
Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health
Moré MI et al. · Journal of Endocrinology and Metabolism · cited by Peptides
In vitro · 2014
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
Chang CH et al. · Molecules · cited by Peptides
Animal · 2014
Pentadecapeptide BPC 157 and anaphylactoid reaction in rats and mice after intravenous dextran and white egg administration
Duplancic B et al. · European Journal of Pharmacology · cited by Peptides
RCT · 2014 · n=114
Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis
Proksch E et al. · Skin Pharmacology and Physiology · cited by Supplements
RCT · 2014 · n=69
Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study
Proksch E et al. · Skin Pharmacology and Physiology · cited by Supplements
In vitro · 2014 · n=29
Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues
Blackburn AR 2nd et al. · BMC Musculoskeletal Disorders · cited by Supplements
RCT · 2014 · n=42
Effect of isometric quadriceps exercise on muscle strength, pain, and function in patients with knee osteoarthritis: a randomized controlled study
Anwer S et al. · Journal of Physical Therapy Science · cited by Exercise & Rehab
Cohort · 2014 · n=1,788
Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study
White DK et al. · Arthritis Care & Research · cited by Exercise & Rehab
Case series · 2014 · n=8
Standardized loads acting in knee implants
Bergmann G et al. · PLoS One · cited by Exercise & Rehab
Animal · 2014
Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
Huang MJ et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition
Cohort · 2014 · n=2,148
Milk consumption and progression of medial tibiofemoral knee osteoarthritis: data from the Osteoarthritis Initiative
Lu B et al. · Arthritis Care & Research (Hoboken) · cited by Foods & Nutrition
Review · 2014
Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis
Shearer MJ et al. · Journal of Lipid Research · cited by Foods & Nutrition
Review · 2014
Does broccoli protect from osteoarthritis?
Berenbaum F · Joint Bone Spine · cited by Foods & Nutrition
Animal · 2014
Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model
Leong DJ et al. · Arthritis Research & Therapy · cited by Foods & Nutrition
RCT · 2014 · n=399
Randomised, controlled trial of avocado-soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study
Maheu E et al. · Annals of the Rheumatic Diseases · cited by Supplements
In vitro · 2014
Chondroitin sulphate distribution in broiler chicken carcasses
Nakano T et al. · British Poultry Science · cited by Foods & Nutrition
In vitro · 2014
Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts
Gruchlik A et al. · Acta Poloniae Pharmaceutica · cited by Peptides
RCT · 2014 · n=74
Resveratrol increases bone mineral density and bone alkaline phosphatase in obese men: a randomized placebo-controlled trial
Ornstrup MJ et al. · The Journal of Clinical Endocrinology and Metabolism · cited by Supplements
RCT · 2014 · n=46
Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults
Witte AV et al. · The Journal of Neuroscience · cited by Supplements
Cohort · 2014 · n=783
Resveratrol levels and all-cause mortality in older community-dwelling adults
Semba RD et al. · JAMA Internal Medicine · cited by Supplements
RCT · 2014 · n=144
Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Two-Year Follow-up of a Prospective Randomized Trial
Saris D et al. · The American Journal of Sports Medicine · cited by Exercise & Rehab and Treatments & Surgery
Registry · 2014
Survey of the therapeutic approach and efficacy of pentosan polysulfate for the prevention and treatment of equine osteoarthritis in veterinary practice in Australia
Kramer CM et al. · Australian Veterinary Journal · cited by Peptides
Review · 2014
First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics
Szeto HH · British Journal of Pharmacology · cited by Peptides
Animal · 2014
Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment
Frohbergh M et al. · PLoS One · cited by Peptides
Animal · 2014 · n=16
Treatment of experimentally induced osteoarthritis in horses using an intravenous combination of sodium pentosan polysulfate, N-acetyl glucosamine, and sodium hyaluronan
Koenig TJ et al. · Veterinary Surgery · cited by Peptides
RCT · 2014 · n=367
Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study
Kuptniratsaikul V et al. · Clinical Interventions in Aging · cited by Supplements
RCT · 2014 · n=40
Curcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trial
Panahi Y et al. · Phytotherapy Research · cited by Supplements
RCT · 2014 · n=50
Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study
Nakagawa Y et al. · Journal of Orthopaedic Science · cited by Supplements
RCT · 2014 · n=100
Lipid-modifying effects of adjunctive therapy with curcuminoids-piperine combination in patients with metabolic syndrome: results of a randomized controlled trial
Panahi Y et al. · Complementary Therapies in Medicine · cited by Supplements
Animal · 2014
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
Matsuzaki T et al. · Annals of the Rheumatic Diseases · cited by Supplements
Animal · 2014
Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis
Kim JH et al. · Cell · cited by Supplements
In vitro · 2014
Cereal foods are the major source of betaine in the Western diet--analysis of betaine and free choline in cereal foods and updated assessments of betaine intake
Ross AB et al. · Food Chemistry · cited by Supplements
Cohort · 2014 · n=475
Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study
Lever M et al. · PLoS One · cited by Supplements
Cohort · 2014 · n=3,903
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide
Wang Z et al. · European Heart Journal · cited by Supplements
RCT · 2014 · n=200
Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study
Caluwé R et al. · Nephrology, Dialysis, Transplantation · cited by Supplements
Animal · 2014 · n=15
Increasing the Dose of Autologous Chondrocytes Improves Articular Cartilage Repair: Histological and Molecular Study in the Sheep Animal Model
Guillén-García P et al. · Cartilage · cited by Treatments & Surgery
Case series · 2014 · n=63
Distal Femoral Fresh Osteochondral Allografts: Follow-up at a Mean of Twenty-two Years
Raz G et al. · The Journal of Bone and Joint Surgery. American Volume · cited by Treatments & Surgery
Animal · 2014
A dose-response study of thymosin β4 for the treatment of acute stroke
Morris DC et al. · Journal of the Neurological Sciences · cited by Peptides
Animal · 2014
In vivo growth suppression of CT-26 mouse colorectal cancer cells by adenovirus-expressed small hairpin RNA specifically targeting thymosin beta-4 mRNA
Chao TC et al. · Cancer Gene Therapy · cited by Peptides
Review · 2013 · n=893
Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans
Stier H et al. · Journal of Endocrinology and Metabolism · cited by Peptides
Systematic review · 2013 · n=19
The basic science of continuous passive motion in promoting knee health: a systematic review of studies in a rabbit model
Knapik DM et al. · Arthroscopy · cited by Exercise & Rehab
Cohort · 2013 · n=2,149
Soft drink intake and progression of radiographic knee osteoarthritis: data from the osteoarthritis initiative
Lu B et al. · BMJ Open · cited by Foods & Nutrition
RCT · 2013 · n=58
Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee
Schumacher HR et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
Animal · 2013
Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo
Davidson RK et al. · Arthritis and Rheumatism · cited by Foods & Nutrition
Animal · 2013
Sulforaphane-PLGA microspheres for the intra-articular treatment of osteoarthritis
Ko JY et al. · Biomaterials · cited by Foods & Nutrition
In vitro · 2013
The risk of lead contamination in bone broth diets
Monro JA et al. · Medical Hypotheses · cited by Foods & Nutrition
RCT · 2013 · n=454
Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial
Messier SP et al. · JAMA · cited by Foods & Nutrition
Animal · 2013 · n=23
Effects of topical copper tripeptide complex on wound healing in an irradiated rat model
Parker NP et al. · Otolaryngology–Head and Neck Surgery · cited by Peptides
Systematic review · 2013 · n=1,301
Do thermal agents affect range of movement and mechanical properties in soft tissues? A systematic review
Bleakley CM et al. · Archives of Physical Medicine and Rehabilitation · cited by Light, Heat & Devices
RCT · 2013 · n=78
Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial
Patel S et al. · The American Journal of Sports Medicine · cited by Injections
Review · 2013
Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition
Jevsevar DS · The Journal of the American Academy of Orthopaedic Surgeons · cited by Injections
RCT · 2013 · n=90
Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial
Rabago D et al. · Annals of Family Medicine · cited by Injections
In vitro · 2013
Evidence for a common mechanism of SIRT1 regulation by allosteric activators
Hubbard BP et al. · Science · cited by Supplements
RCT · 2013 · n=24
High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
Poulsen MM et al. · Diabetes · cited by Supplements
RCT · 2013 · n=27
Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men
Gliemann L et al. · The Journal of Physiology · cited by Supplements
RCT · 2013 · n=351
Surgery versus physical therapy for a meniscal tear and osteoarthritis
Katz JN et al. · The New England Journal of Medicine · cited by Treatments & Surgery
Animal · 2013
Thymosin β4 enhances the healing of medial collateral ligament injury in rat
Xu B et al. · Regulatory Peptides · cited by Peptides
Cohort · 2013 · n=216
Increased thymosin β4 levels in the serum and SF of knee osteoarthritis patients correlate with disease severity
Wei M et al. · Regulatory Peptides · cited by Peptides
Animal · 2013
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin
Birk AV et al. · Journal of the American Society of Nephrology · cited by Peptides
RCT · 2013 · n=8
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers
Volak LP et al. · British Journal of Clinical Pharmacology · cited by Supplements
In vitro · 2013
Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1
Wang YM et al. · Toxicology and Applied Pharmacology · cited by Supplements
RCT · 2013 · n=55
Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers
Lugo JP et al. · Journal of the International Society of Sports Nutrition · cited by Supplements
Animal · 2013
Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model
Ezaki J et al. · Journal of Bone and Mineral Metabolism · cited by Supplements
Cohort · 2013 · n=1,180
Vitamin K deficiency is associated with incident knee osteoarthritis
Misra D et al. · The American Journal of Medicine · cited by Foods & Nutrition and Supplements
RCT · 2013 · n=146
Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial
McAlindon T et al. · JAMA · cited by Supplements
Meta-analysis · 2013
Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis
McRae MP · Journal of Chiropractic Medicine · cited by Supplements
Animal · 2013
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
Gomes AP et al. · Cell · cited by Supplements
RCT · 2013 · n=18
Effect of low-dose supplements of menaquinone-7 (vitamin K2) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers
Theuwissen E et al. · Journal of Thrombosis and Haemostasis · cited by Supplements
RCT · 2013 · n=244
Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women
Knapen MH et al. · Osteoporosis International · cited by Supplements
Review · 2013
Menatetrenone for the treatment of osteoporosis
Iwamoto J et al. · Expert Opinion on Pharmacotherapy · cited by Supplements
Cohort · 2013 · n=77
Preoperative MRI underestimates articular cartilage defect size compared with findings at arthroscopic knee surgery
Campbell AB et al. · The American Journal of Sports Medicine · cited by 1 page
Systematic review · 2013 · n=3,122
Evidence-based status of microfracture technique: a systematic review of level I and II studies
Goyal D et al. · Arthroscopy · cited by Treatments & Surgery
Case series · 2013 · n=122
Do fresh osteochondral allografts successfully treat femoral condyle lesions?
Levy YD et al. · Clinical Orthopaedics and Related Research · cited by Treatments & Surgery
Systematic review · 2013 · n=644
Outcomes of osteochondral allograft transplantation in the knee
Chahal J et al. · Arthroscopy · cited by Treatments & Surgery
Cohort · 2013 · n=43
A non-randomized controlled clinical trial on autologous chondrocyte implantation (ACI) in cartilage defects of the medial femoral condyle with or without high tibial osteotomy in patients with varus deformity of less than 5°
Bode G et al. · Archives of Orthopaedic and Trauma Surgery · cited by Treatments & Surgery
Cohort · 2012 · n=3
The distribution pattern of critically short telomeres in human osteoarthritic knees
Harbo M et al. · Arthritis Res Ther · cited by Peptides
Review · 2012
Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157
Sikiric P et al. · Current Medicinal Chemistry · cited by Peptides
Animal · 2012
Distribution of prolylhydroxyproline and its metabolites after oral administration in rats
Kawaguchi T et al. · Biological and Pharmaceutical Bulletin · cited by Foods & Nutrition and Supplements
Systematic review · 2012
Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review
Van Vijven JP et al. · Osteoarthritis and Cartilage · cited by Supplements
RCT · 2012 · n=200
Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study
Bruyère O et al. · Complementary Therapies in Medicine · cited by Supplements
Case series · 2012
Quantification of hydroxyprolyl-glycine (Hyp-Gly) in human blood after ingestion of collagen hydrolysate
Sugihara F et al. · Journal of Bioscience and Bioengineering · cited by Supplements
Cohort · 2012 · n=2,112
Association of dietary magnesium intake with radiographic knee osteoarthritis: results from a population-based study
Qin B et al. · Arthritis Care & Research (Hoboken) · cited by Foods & Nutrition
RCT · 2012 · n=77
An un-commissioned randomized, placebo-controlled double-blind study to test the effect of deep sea fish oil as a pain reliever for dogs suffering from canine OA
Hielm-Björkman A et al. · BMC Veterinary Research · cited by Foods & Nutrition
Cohort · 2012 · n=633
Cherry consumption and decreased risk of recurrent gout attacks
Zhang Y et al. · Arthritis and Rheumatism · cited by Foods & Nutrition
Review · 2012
Dietary polyphenols and mechanisms of osteoarthritis
Shen CL et al. · The Journal of Nutritional Biochemistry · cited by Foods & Nutrition
In vitro · 2012
Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes
Fragoulis A et al. · Arthritis Research & Therapy · cited by Foods & Nutrition
In vitro · 2012
Sulforaphane inhibits proliferation by causing cell cycle arrest at the G2/M phase in rabbit articular chondrocytes
Jeong HJ et al. · Molecular Medicine Reports · cited by Foods & Nutrition
Cohort · 2012 · n=472
Association of plasma n-6 and n-3 polyunsaturated fatty acids with synovitis in the knee: the MOST study
Baker KR et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition
Cohort · 2012 · n=111
Weight loss in obese people has structure-modifying effects on medial but not on lateral knee articular cartilage
Anandacoomarasamy A et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition
In vitro · 2012
Stem cell recovering effect of copper-free GHK in skin
Choi HR et al. · Journal of Peptide Science · cited by Peptides
In vitro · 2012
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK
Campbell JD et al. · Genome Medicine · cited by Peptides
In vitro · 2012
Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts
Gruchlik A et al. · Acta Poloniae Pharmaceutica · cited by Peptides
Meta-analysis · 2012 · n=12,667
Viscosupplementation for osteoarthritis of the knee: a systematic review and meta-analysis
Rutjes AW et al. · Annals of Internal Medicine · cited by Injections
Cohort · 2012 · n=49
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue
Massudi H et al. · PLoS One · cited by Supplements
RCT · 2012 · n=29
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance
Yoshino J et al. · Cell Metabolism · cited by Supplements
Review · 2012
The basic science of human knee menisci: structure, composition, and function
Fox AJ et al. · Sports Health · cited by Treatments & Surgery
Meta-analysis · 2012 · n=566
Meniscal repair outcomes at greater than five years: a systematic literature review and meta-analysis
Nepple JJ et al. · The Journal of Bone and Joint Surgery. American Volume · cited by Treatments & Surgery
Meta-analysis · 2012 · n=409
Neuromuscular electrical stimulation in the treatment of knee osteoarthritis: a systematic review and meta-analysis
Giggins O et al. · Clinical Rehabilitation · cited by Light, Heat & Devices
RCT · 2012 · n=66
Early neuromuscular electrical stimulation to improve quadriceps muscle strength after total knee arthroplasty: a randomized controlled trial
Stevens-Lapsley JE et al. · Physical Therapy · cited by Light, Heat & Devices
Animal · 2012 · n=18
Evaluation of intramuscularly administered sodium pentosan polysulfate for treatment of experimentally induced osteoarthritis in horses
McIlwraith CW et al. · American Journal of Veterinary Research · cited by Peptides
Cohort · 2012 · n=62
Application of bioregulating therapy in complex treatment of temporomandibular joint diseases in people of elderly and senile age
Iordanishvili AK et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
In vitro · 2012
Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
Troeberg L et al. · The Biochemical Journal · cited by Peptides
Systematic review · 2012
The effect of smoking on ligament and cartilage surgery in the knee: a systematic review
Kanneganti P et al. · The American Journal of Sports Medicine · cited by Precautions
RCT · 2012 · n=88
The efficacy of Curcuma Longa L. extract as an adjuvant therapy in primary knee osteoarthritis: a randomized control trial
Pinsornsak P et al. · Journal of the Medical Association of Thailand · cited by Supplements
RCT · 2012 · n=60
Oral administration of polymer hyaluronic acid alleviates symptoms of knee osteoarthritis: a double-blind, placebo-controlled study over a 12-month period
Tashiro T et al. · The Scientific World Journal · cited by Supplements
RCT · 2012 · n=80
Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: a randomized, double-blind, placebo-controlled trial
Schauss AG et al. · Journal of Agricultural and Food Chemistry · cited by Foods & Nutrition
RCT · 2012 · n=10
Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women
Sato T et al. · Nutrition Journal · cited by Supplements
RCT · 2012
Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance
del Favero S et al. · Amino Acids · cited by Supplements
RCT · 2012 · n=42
Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects
Theuwissen E et al. · British Journal of Nutrition · cited by Supplements
RCT · 2012 · n=53
Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial
Westenfeld R et al. · American Journal of Kidney Diseases · cited by Supplements
RCT · 2012 · n=57
Ten-year follow-up of a prospective, randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint of athletes
Gudas R et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
In vitro · 2012
Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential
Esposito S et al. · Drug Testing and Analysis · cited by Peptides
Animal · 2012
Doping control analysis of TB-500, a synthetic version of an active region of thymosin β4, in equine urine and plasma by liquid chromatography-mass spectrometry
Ho EN et al. · Journal of Chromatography A · cited by Peptides
Animal · 2012
Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes
Zhou B et al. · Journal of Molecular and Cellular Cardiology · cited by Peptides
Review · 2012
The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients
Treadwell T et al. · Annals of the New York Academy of Sciences · cited by Peptides
In vitro · 2011
[The geroprotective effect of the amino acids and tripeptides in the cartilage tissue culture in rats]
Smirnov AV et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
In vitro · 2011
Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA
Fedoreyeva LI et al. · Biochemistry (Moscow) · cited by Peptides
Animal · 2011
Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions
Ilic S et al. · Life Sciences · cited by Peptides
RCT · 2011 · n=30
Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
McAlindon TE et al. · Osteoarthritis and Cartilage · cited by Supplements
Case series · 2011 · n=5
Identification of a novel food-derived collagen peptide, hydroxyprolyl-glycine, in human peripheral blood by pre-column derivatisation with phenyl isothiocyanate
Shigemura Y et al. · Food Chemistry · cited by Supplements
Cohort · 2011 · n=35,331
Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study
Wang Y et al. · BMC Musculoskeletal Disorders · cited by Foods & Nutrition
In vitro · 2011
Sulforaphane protects human chondrocytes against cell death induced by various stimuli
Facchini A et al. · Journal of Cellular Physiology · cited by Foods & Nutrition
In vitro · 2011
Human skin penetration of a copper tripeptide in vitro as a function of skin layer
Hostynek JJ et al. · Inflammation Research · cited by Peptides
Animal · 2011
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
Burnett C et al. · Nature · cited by Supplements
Animal · 2011
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
Miller RA et al. · The Journals of Gerontology, Series A · cited by Supplements
RCT · 2011 · n=11
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Timmers S et al. · Cell Metabolism · cited by Supplements
In vitro · 2011
The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
Chang CH et al. · Journal of Applied Physiology · cited by Peptides
Review · 2011
The role of mitochondria in osteoarthritis
Blanco FJ et al. · Nature Reviews Rheumatology · cited by Peptides
Systematic review · 2011 · n=16,184
Ciprofloxacin safety in paediatrics: a systematic review
Adefurin A et al. · Archives of Disease in Childhood · cited by Precautions
Meta-analysis · 2011 · n=537,730
Does smoking protect against osteoarthritis? Meta-analysis of observational studies
Hui M et al. · Annals of the Rheumatic Diseases · cited by Precautions
RCT · 2011 · n=50
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study
Debbi EM et al. · BMC Complementary and Alternative Medicine · cited by Supplements
Meta-analysis · 2011 · n=326
Meta-analysis of the related nutritional supplements dimethyl sulfoxide and methylsulfonylmethane in the treatment of osteoarthritis of the knee
Brien S et al. · Evidence-Based Complementary and Alternative Medicine · cited by Foods & Nutrition and Supplements
RCT · 2011 · n=24
Beneficial effect of creatine supplementation in knee osteoarthritis
Neves M Jr et al. · Medicine and Science in Sports and Exercise · cited by Supplements
RCT · 2011 · n=63
Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects
Schwab U et al. · European Journal of Clinical Nutrition · cited by Supplements
In vitro · 2011
Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation
Thaler R et al. · The Journal of Biological Chemistry · cited by Supplements
Case series · 2011 · n=413
Long-term survival of high tibial osteotomy for medial compartment osteoarthritis of the knee
Hui C et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
In vitro · 2011
Muscle injury-induced thymosin β4 acts as a chemoattractant for myoblasts
Tokura Y et al. · Journal of Biochemistry · cited by Peptides
Cohort · 2011
Increased levels of thymosin β4 in synovial fluid of patients with rheumatoid arthritis: association of thymosin β4 with other factors that are involved in inflammation and bone erosion in joints
Choi HM et al. · International Journal of Rheumatic Diseases · cited by Peptides
In vitro · 2011
Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway
Tang MC et al. · Cancer Letters · cited by Peptides
Animal · 2010
Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application
Pevec D et al. · Medical Science Monitor · cited by Peptides
Animal · 2010
Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury
Gjurasin M et al. · Regulatory Peptides · cited by Peptides
Animal · 2010
Effects of Pro-Hyp, a collagen hydrolysate-derived peptide, on hyaluronic acid synthesis using in vitro cultured synovium cells and oral ingestion of collagen hydrolysates in a guinea pig model of osteoarthritis
Ohara H et al. · Bioscience, Biotechnology, and Biochemistry · cited by Supplements
Cohort · 2010 · n=36
Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
von Engelhardt LV et al. · BMC Musculoskeletal Disorders · cited by 1 page
Cohort · 2010 · n=1,829
Effect of quadriceps strength and proprioception on risk for knee osteoarthritis
Segal NA et al. · Medicine and Science in Sports and Exercise · cited by Exercise & Rehab
RCT · 2010 · n=70
A Prospective, Randomized Comparison of Traditional and Accelerated Approaches to Postoperative Rehabilitation following Autologous Chondrocyte Implantation
Ebert JR et al. · Cartilage · cited by Exercise & Rehab
Systematic review · 2010 · n=16
Continuous Passive Motion, Early Weight Bearing, and Active Motion following Knee Articular Cartilage Repair: Evidence for Clinical Practice
Howard JS et al. · Cartilage · cited by Exercise & Rehab
RCT · 2010 · n=127
Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs
Roush JK et al. · Journal of the American Veterinary Medical Association · cited by Foods & Nutrition
In vitro · 2010
Advanced glycation end products in foods and a practical guide to their reduction in the diet
Uribarri J et al. · Journal of the American Dietetic Association · cited by Foods & Nutrition
Review · 2010
Dietary advanced glycation end products and aging
Luevano-Contreras C et al. · Nutrients · cited by Foods & Nutrition
Animal · 2010
Chondroprotective effects of pomegranate juice on monoiodoacetate-induced osteoarthritis of the knee joint of mice
Hadipour-Jahromy M et al. · Phytotherapy Research · cited by Foods & Nutrition
In vitro · 2010
Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes
Rasheed Z et al. · Arthritis Research & Therapy · cited by Foods & Nutrition
Case series · 2010 · n=40
Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis
Brown VA et al. · Cancer Research · cited by Supplements
Animal · 2010
Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat
Cerovecki T et al. · Journal of Orthopaedic Research · cited by Peptides
In vitro · 2010
Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells
Ghosh P et al. · Arthritis Research & Therapy · cited by Peptides
Cohort · 2010 · n=20
Sodium pentosan polysulfate resulted in cartilage improvement in knee osteoarthritis--an open clinical trial
Kumagai K et al. · BMC Clinical Pharmacology · cited by Peptides
Cohort · 2010 · n=20
High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage?
Luke AC et al. · The American Journal of Sports Medicine · cited by Precautions
RCT · 2010 · n=662
Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT
Sawitzke AD et al. · Annals of the Rheumatic Diseases · cited by Supplements
Meta-analysis · 2010 · n=3,803
Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis
Wandel S et al. · BMJ · cited by Supplements
RCT · 2010 · n=60
Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study
Sengupta K et al. · International Journal of Medical Sciences · cited by Supplements
Cohort · 2010 · n=100
Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients
Belcaro G et al. · Alternative Medicine Review · cited by Supplements
Review · 2010
Biological actions of curcumin on articular chondrocytes
Henrotin Y et al. · Osteoarthritis and Cartilage · cited by Supplements
RCT · 2010 · n=71
The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combination
Jackson CG et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition and Supplements
In vitro · 2010
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1
Pacholec M et al. · The Journal of Biological Chemistry · cited by Supplements
RCT · 2010 · n=60
Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study
Basad E et al. · Knee Surgery, Sports Traumatology, Arthroscopy · cited by Treatments & Surgery
Case series · 2010 · n=224
Autologous chondrocyte implantation: a long-term follow-up
Peterson L et al. · The American Journal of Sports Medicine · cited by Treatments & Surgery
Review · 2010
Multifunctionality of the beta-thymosin/WH2 module: G-actin sequestration, actin filament growth, nucleation, and severing
Husson C et al. · Annals of the New York Academy of Sciences · cited by Peptides
Review · 2010
Biological activities of thymosin beta4 defined by active sites in short peptide sequences
Sosne G et al. · The FASEB Journal · cited by Peptides
RCT · 2010 · n=72
The effect of thymosin treatment of venous ulcers
Guarnera G et al. · Annals of the New York Academy of Sciences · cited by Peptides
RCT · 2010 · n=30
A Phase 2 Study on Effect of Thymosin Beta 4 on Wound Healing in Patients With Epidermolysis Bullosa
RegeneRx Biopharmaceuticals, Inc. · ClinicalTrials.gov registration with posted results · cited by Peptides
Animal · 2010
Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse
Spurney CF et al. · PLoS One · cited by Peptides
Animal · 2010
Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors
Hamm CA et al. · BMC Cancer · cited by Peptides
Animal · 2009
[Morphological characteristics of bone tissue regeneration process in young and old animals]
Kurilov IN et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Animal · 2009
Effect of peptide bioregulator on healing of excision wounds in old animals
Kurilov IN et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
Animal · 2009
Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing
Brcic L et al. · Journal of Physiology and Pharmacology · cited by Peptides
Animal · 2009
Gastric pentadecapeptide BPC 157 and short bowel syndrome in rats
Sever M et al. · Digestive Diseases and Sciences · cited by Peptides
Animal · 2009
Antiinflammatory effect of BPC 157 on experimental periodontitis in rats
Keremi B et al. · Journal of Physiology and Pharmacology · cited by Peptides
Animal · 2009
Chondroprotective effect of the bioactive peptide prolyl-hydroxyproline in mouse articular cartilage in vitro and in vivo
Nakatani S et al. · Osteoarthritis and Cartilage · cited by Foods & Nutrition and Supplements
Cohort · 2009 · n=2,275
Knee extensor strength does not protect against incident knee symptoms at 30 months in the multicenter knee osteoarthritis (MOST) cohort
Segal NA et al. · PM&R · cited by Exercise & Rehab
In vitro · 2009 · n=180
Sensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oils
Cicerale S et al. · Chemical Senses · cited by Foods & Nutrition
Review · 2009
A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis
Meléndez-Hevia E et al. · Journal of Biosciences · cited by Foods & Nutrition
In vitro · 2009
Copper-GHK increases integrin expression and p63 positivity by keratinocytes
Kang YA et al. · Archives of Dermatological Research · cited by Peptides
Case series · 2009 · n=34
Infrared sauna in patients with rheumatoid arthritis and ankylosing spondylitis. A pilot study showing good tolerance, short-term improvement of pain and stiffness, and a trend towards long-term beneficial effects
Oosterveld FG et al. · Clinical Rheumatology · cited by Light, Heat & Devices
Systematic review · 2009
Knee osteoarthritis after anterior cruciate ligament injury: a systematic review
Øiestad BE et al. · The American Journal of Sports Medicine · cited by Precautions
Cohort · 2009 · n=271
Smoking is associated with increased cartilage loss and persistence of bone marrow lesions over 2 years in community-based individuals
Davies-Tuck ML et al. · Rheumatology (Oxford) · cited by Precautions
Cohort · 2009 · n=114
Does smoking influence outcome after autologous chondrocyte implantation?: A case-controlled study
Jaiswal PK et al. · The Journal of Bone and Joint Surgery. British Volume · cited by Precautions
RCT · 2009 · n=8
Vibration training intervention to maintain cartilage thickness and serum concentrations of cartilage oligometric matrix protein (COMP) during immobilization
Liphardt AM et al. · Osteoarthritis and Cartilage · cited by Precautions
In vitro · 2009
Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis
Csaki C et al. · Arthritis Research & Therapy · cited by Supplements
RCT · 2009 · n=52
Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial
Crowley DC et al. · International Journal of Medical Sciences · cited by Supplements
RCT · 2009 · n=67
Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study
Ruff KJ et al. · Clinical Rheumatology · cited by Supplements
Case series · 2009 · n=39
Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies
Ruff KJ et al. · Clinical Interventions in Aging · cited by Supplements
RCT · 2009 · n=503
A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis
Wei W et al. · Arthritis Research & Therapy · cited by Supplements
RCT · 2009 · n=55
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Abdelmalek MF et al. · Hepatology · cited by Supplements
Meta-analysis · 2009 · n=656
S-Adenosylmethionine for osteoarthritis of the knee or hip
Rutjes AW et al. · Cochrane Database of Systematic Reviews · cited by Supplements
RCT · 2009 · n=4,378
Randomized controlled study on the prevention of osteoporotic fractures (OF study): a phase IV clinical study of 15-mg menatetrenone capsules
Inoue T et al. · Journal of Bone and Mineral Metabolism · cited by Supplements
Systematic review · 2009 · n=3,122
Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis
Mithoefer K et al. · The American Journal of Sports Medicine · cited by Exercise & Rehab and Treatments & Surgery
In vitro · 2009
Exogenous thymosin beta4 prevents apoptosis in human intervertebral annulus cells in vitro
Tapp H et al. · Biotechnic & Histochemistry · cited by Peptides
Animal · 2008 · n=72
Modulation of early functional recovery of Achilles tendon to bone unit after transection by BPC 157 and methylprednisolone
Krivic A et al. · Inflammation Research · cited by Peptides
Animal · 2008
Gastric pentadecapeptide BPC 157 as an effective therapy for muscle crush injury in the rat
Novinscak T et al. · Surgery Today · cited by Peptides
RCT · 2008 · n=147
24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain
Clark KL et al. · Current Medical Research and Opinion · cited by Supplements
Cohort · 2008 · n=98
Long distance running and knee osteoarthritis. A prospective study
Chakravarty EF et al. · American Journal of Preventive Medicine · cited by Exercise & Rehab
In vitro · 2008 · n=6
Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro
Shukla M et al. · Journal of Inflammation (London) · cited by Foods & Nutrition
Meta-analysis · 2008 · n=287
Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?--a meta-analysis of randomized controlled trials
Christensen R et al. · Osteoarthritis and Cartilage · cited by Supplements
Systematic review · 2008
A systematic review on the Rosa canina effect and efficacy profiles
Chrubasik C et al. · Phytotherapy Research · cited by Supplements
Meta-analysis · 2008 · n=664
Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials
Christensen R et al. · Osteoarthritis and Cartilage · cited by Supplements
RCT · 2008 · n=65
Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial
Nass R et al. · Annals of Internal Medicine · cited by Peptides
Case series · 2008 · n=13
Efficacy of Waon therapy for fibromyalgia
Matsushita K et al. · Internal Medicine · cited by Light, Heat & Devices
Animal · 2008
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
Pearson KJ et al. · Cell Metabolism · cited by Supplements
Cohort · 2008 · n=991
Incidental meniscal findings on knee MRI in middle-aged and elderly persons
Englund M et al. · The New England Journal of Medicine · cited by Treatments & Surgery
In vitro · 2008
Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases
Troeberg L et al. · FASEB Journal · cited by Peptides
In vitro · 2008
Calcium pentosan polysulfate directly inhibits enzymatic activity of ADAMTS4 (aggrecanase-1) in osteoarthritic chondrocytes
Takizawa M et al. · FEBS Letters · cited by Peptides
RCT · 2008 · n=75
A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee
Sengupta K et al. · Arthritis Research & Therapy · cited by Supplements
RCT · 2008 · n=20
Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial
Kalman DS et al. · Nutrition Journal · cited by Supplements
RCT · 2008 · n=378
Vitamin K in hand osteoarthritis: results from a randomised clinical trial
Neogi T et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition and Supplements
In vitro · 2008
Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: possible influence on osteoarthritis
Gosset M et al. · Arthritis and Rheumatism · cited by Supplements
Case series · 2008 · n=4
Denture cream: an unusual source of excess zinc, leading to hypocupremia and neurologic disease
Nations SP et al. · Neurology · cited by Supplements
RCT · 2008 · n=72
Study of Thymosin Beta 4 in Patients With Pressure Ulcers
RegeneRx Biopharmaceuticals, Inc. · ClinicalTrials.gov registration with posted results · cited by Peptides
Animal · 2007
[Effect of peptide regulators on the structural and functional status of bone tissue in ageing rats]
Povorozniuk VV et al. · Advances in Gerontology (Uspekhi Gerontologii) · cited by Peptides
Animal · 2007
Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression
Tkalcević VI et al. · European Journal of Pharmacology · cited by Peptides
RCT · 2007 · n=5
Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources
Ohara H et al. · Journal of Agricultural and Food Chemistry · cited by Foods & Nutrition and Supplements
Meta-analysis · 2007 · n=454
Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis
Christensen R et al. · Annals of the Rheumatic Diseases · cited by Foods & Nutrition
In vitro · 2007
In vitro observations on the influence of copper peptide aids for the LED photoirradiation of fibroblast collagen synthesis
Huang PJ et al. · Photomedicine and Laser Surgery · cited by Peptides
Animal · 2007
A therapeutic approach for diabetic wound healing using biotinylated GHK incorporated collagen matrices
Arul V et al. · Life Sciences · cited by Peptides
Animal · 2007
Evaluation of pentosan polysulfate sodium in the postoperative recovery from cranial cruciate injury in dogs: a randomized, placebo-controlled clinical trial
Budsberg SC et al. · Veterinary Surgery · cited by Peptides
RCT · 2007 · n=38
Continued sports activity, using a pain-monitoring model, during rehabilitation in patients with Achilles tendinopathy: a randomized controlled study
Silbernagel KG et al. · The American Journal of Sports Medicine · cited by Exercise & Rehab and Precautions
Review · 2007
The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis
Lohmander LS et al. · The American Journal of Sports Medicine · cited by Precautions
Animal · 2007 · n=48
Diminished ciprofloxacin-induced chondrotoxicity by supplementation with magnesium and vitamin E in immature rats
Pfister K et al. · Antimicrobial Agents and Chemotherapy · cited by Precautions
Cohort · 2007 · n=159
Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritis
Amin S et al. · Annals of the Rheumatic Diseases · cited by Precautions
RCT · 2007 · n=18
Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers
Haack M et al. · Sleep · cited by Precautions
Cohort · 2007 · n=992
Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies
Felson DT et al. · Arthritis and Rheumatism · cited by Supplements
RCT · 2007
Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7
Schurgers LJ et al. · Blood · cited by Supplements
Cohort · 2007 · n=25,124
Articular cartilage defects: study of 25,124 knee arthroscopies
Widuchowski W et al. · The Knee · cited by 1 page
Animal · 2007
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization
Smart N et al. · Nature · cited by Peptides
In vitro · 2007
Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase
Huang HC et al. · Oncogene · cited by Peptides
Animal · 2006
Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157
Staresinic M et al. · Journal of Orthopaedic Research · cited by Peptides
Animal · 2006
Accelerated healing of excisional skin wounds by PL 14736 in alloxan-hyperglycemic rats
Seveljević-Jaran D et al. · Skin Pharmacology and Physiology · cited by Peptides
Review · 2006
Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response
Sikiric P et al. · Inflammopharmacology · cited by Peptides
Case series · 2006
Hydroxyproline ingestion and urinary oxalate and glycolate excretion
Knight J et al. · Kidney International · cited by Supplements
Animal · 2006 · n=18
Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits
Cangul IT et al. · Veterinary Dermatology · cited by Peptides
RCT · 2006 · n=13
Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
Miller TR et al. · Archives of Facial Plastic Surgery · cited by Peptides
In vitro · 2006
Glutamine protects articular chondrocytes from heat stress and NO-induced apoptosis with HSP70 expression
Tonomura H et al. · Osteoarthritis and Cartilage · cited by Light, Heat & Devices
Animal · 2006
Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis
Grossin L et al. · The FASEB Journal · cited by Light, Heat & Devices
Review · 2006
Health effects and risks of sauna bathing
Kukkonen-Harjula K et al. · International Journal of Circumpolar Health · cited by Light, Heat & Devices
Animal · 2006
Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation
Krivic A et al. · Journal of Orthopaedic Research · cited by Peptides
RCT · 2006 · n=1,583
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Clegg DO et al. · The New England Journal of Medicine · cited by Foods & Nutrition and Supplements
RCT · 2006 · n=50
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial
Kim LS et al. · Osteoarthritis and Cartilage · cited by Supplements
Cohort · 2006 · n=672
Low vitamin K status is associated with osteoarthritis in the hand and knee
Neogi T et al. · Arthritis and Rheumatism · cited by Foods & Nutrition and Supplements
Review · 2006
Copper deficiency myelopathy (human swayback)
Kumar N · Mayo Clinic Proceedings · cited by Supplements
RCT · 2006 · n=10
Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans
Schwab U et al. · The Journal of Nutrition · cited by Supplements
Cohort · 2006 · n=85
Results after microfracture of full-thickness chondral defects in different compartments in the knee
Kreuz PC et al. · Osteoarthritis and Cartilage · cited by Treatments & Surgery
RCT · 2006 · n=68
A prospective, randomised study comparing two techniques of autologous chondrocyte implantation for osteochondral defects in the knee: Periosteum covered versus type I/III collagen covered
Gooding CR et al. · The Knee · cited by Treatments & Surgery
In vitro · 2005
Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2
McNulty AL et al. · Biochimica et Biophysica Acta · cited by Supplements
In vitro · 2005
Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint
McNulty AL et al. · Arthritis and Rheumatism · cited by Supplements
RCT · 2005 · n=30
Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritis
Roos EM et al. · Arthritis and Rheumatism · cited by Exercise & Rehab
Case series · 2005 · n=50
In vivo cartilage deformation after different types of activity and its dependence on physical training status
Eckstein F et al. · Annals of the Rheumatic Diseases · cited by Exercise & Rehab
In vitro · 2005
Phytochemistry: ibuprofen-like activity in extra-virgin olive oil
Beauchamp GK et al. · Nature · cited by Foods & Nutrition
Case series · 2005
Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates
Iwai K et al. · Journal of Agricultural and Food Chemistry · cited by Foods & Nutrition and Supplements
In vitro · 2005
Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts
Pollard JD et al. · Archives of Facial Plastic Surgery · cited by Peptides
Animal · 2005
Biotinylated GHK peptide incorporated collagenous matrix: A novel biomaterial for dermal wound healing in rats
Arul V et al. · Journal of Biomedical Materials Research Part B: Applied Biomaterials · cited by Peptides
Cohort · 2005
Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study
Reijman M et al. · Arthritis & Rheumatism · cited by Precautions
RCT · 2005 · n=114
Effects of pentosan polysulfate in osteoarthritis of the knee: A randomized, double-blind, placebo-controlled pilot study
Ghosh P et al. · Current Therapeutic Research, Clinical and Experimental · cited by Peptides
RCT · 2005 · n=380
Randomized, double-blind, dose-ranging study of pentosan polysulfate sodium for interstitial cystitis
Nickel JC et al. · Urology · cited by Peptides
Cohort · 2005 · n=16
Metabolism of [3H]pentosan polysulfate sodium (PPS) in healthy human volunteers
Simon M et al. · Xenobiotica · cited by Peptides
RCT · 2005
Pharmacokinetics and pharmacodynamics of warfarin when coadministered with pentosan polysulfate sodium
Modi NB et al. · Journal of Clinical Pharmacology · cited by Peptides
In vitro · 2005
Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells
Sendzik J et al. · Toxicology · cited by Precautions
RCT · 2005 · n=37
Creatine monohydrate supplementation does not improve functional recovery after total knee arthroplasty
Roy BD et al. · Archives of Physical Medicine and Rehabilitation · cited by Supplements
RCT · 2005 · n=151
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans
Olthof MR et al. · PLoS Medicine · cited by Supplements
Cohort · 2005 · n=500
Betaine and folate status as cooperative determinants of plasma homocysteine in humans
Holm PI et al. · Arteriosclerosis, Thrombosis, and Vascular Biology · cited by Supplements
RCT · 2005 · n=57
A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes
Gudas R et al. · Arthroscopy · cited by Treatments & Surgery
RCT · 2005 · n=91
Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study
Bartlett W et al. · The Journal of Bone and Joint Surgery. British Volume · cited by Treatments & Surgery
Animal · 2004
Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats
Xue XC et al. · World Journal of Gastroenterology · cited by Peptides
Animal · 2004
Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model
Kraus VB et al. · Arthritis and Rheumatism · cited by Supplements
Case series · 2004 · n=17
Vitamin C pharmacokinetics: implications for oral and intravenous use
Padayatty SJ et al. · Annals of Internal Medicine · cited by Supplements
Cohort · 2004 · n=655
The association of milk consumption with the occurrence of symptomatic knee osteoarthritis
Kaçar C et al. · Clinical and Experimental Rheumatology · cited by Foods & Nutrition
Cohort · 2004 · n=20
Cartilage atrophy in the knees of patients after seven weeks of partial load bearing
Hinterwimmer S et al. · Arthritis and Rheumatism · cited by Exercise & Rehab and Precautions
RCT · 2004 · n=118
Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfonylmethane and their Combination in Osteoarthritis
Usha PR et al. · Clinical Drug Investigation · cited by Supplements
In vitro · 2004
Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes
Schulze-Tanzil G et al. · Annals of the New York Academy of Sciences · cited by Supplements
Cohort · 2004 · n=6
High absorption but very low bioavailability of oral resveratrol in humans
Walle T et al. · Drug Metabolism and Disposition · cited by Supplements
RCT · 2004 · n=34
The effect of low doses of betaine on plasma homocysteine in healthy volunteers
Alfthan G et al. · British Journal of Nutrition · cited by Supplements
Cohort · 2004 · n=4,807
Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study
Geleijnse JM et al. · The Journal of Nutrition · cited by Supplements
RCT · 2004 · n=61
S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]
Najm WI et al. · BMC Musculoskeletal Disorders · cited by Supplements
Animal · 2004
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
Bock-Marquette I et al. · Nature · cited by Peptides
Animal · 2004
Thymosin beta4 increases hair growth by activation of hair follicle stem cells
Philp D et al. · The FASEB Journal · cited by Peptides
In vitro · 2004
Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma
Wang WS et al. · Oncogene · cited by Peptides
Animal · 2003 · n=108
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Anisimov VN et al. · Biogerontology · cited by Peptides
RCT · 2003 · n=266
Peptides of pineal gland and thymus prolong human life
Khavinson VKh et al. · Neuroendocrinology Letters · cited by Peptides
In vitro · 2003
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Khavinson VKh et al. · Bulletin of Experimental Biology and Medicine · cited by Peptides
Animal · 2003
Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice
Sikiric P et al. · Burns · cited by Peptides
Animal · 2003
Ascorbic acid accumulates in cartilage in vivo
Stabler TV et al. · Clinica Chimica Acta · cited by Supplements
RCT · 2003 · n=133
Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice
Jensen NH · Ugeskrift for Laeger · cited by Supplements
Review · 2003
Advanced glycation endproducts and osteoarthritis
Saudek DM et al. · Current Rheumatology Reports · cited by Foods & Nutrition
Animal · 2003 · n=24
The effect of topical tripeptide-copper complex on healing of ischemic open wounds
Canapp SO Jr et al. · Veterinary Surgery · cited by Peptides
Systematic review · 2003 · n=179
Thermotherapy for treatment of osteoarthritis
Brosseau L et al. · Cochrane Database of Systematic Reviews · cited by Light, Heat & Devices
In vitro · 2003
Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes
Terauchi R et al. · Arthritis and Rheumatism · cited by Light, Heat & Devices
In vitro · 2003
Effect of heat stimulation on viability and proteoglycan metabolism of cultured chondrocytes: preliminary report
Hojo T et al. · Journal of Orthopaedic Science · cited by Light, Heat & Devices
Animal · 2003
Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth
Staresinic M et al. · Journal of Orthopaedic Research · cited by Peptides
Registry · 2003
Safety of Cartrophen Vet in the dog: review of adverse reaction reports in the UK
Hannon RL et al. · The Journal of Small Animal Practice · cited by Peptides
RCT · 2003 · n=121
A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis
Sant GR et al. · The Journal of Urology · cited by Peptides
Registry · 2003 · n=51,367
Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids
van der Linden PD et al. · Archives of Internal Medicine · cited by Precautions
RCT · 2003 · n=30
Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial
Kimmatkar N et al. · Phytomedicine · cited by Supplements
Case series · 2003 · n=20
Oral absorption and bioavailability of ichthyic origin chondroitin sulfate in healthy male volunteers
Volpi N · Osteoarthritis and Cartilage · cited by Foods & Nutrition and Supplements
In vitro · 2003
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Howitz KT et al. · Nature · cited by Supplements
RCT · 2003 · n=76
Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women
Olthof MR et al. · The Journal of Nutrition · cited by Supplements
Review · 2003
Evaluation of cartilage injuries and repair
Brittberg M et al. · The Journal of Bone and Joint Surgery. American Volume · cited by 1 page
Case series · 2003 · n=72
Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up
Steadman JR et al. · Arthroscopy · cited by Treatments & Surgery
Case series · 2003 · n=831
Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience
Hangody L et al. · The Journal of Bone and Joint Surgery. American Volume · cited by Treatments & Surgery
Animal · 2003
Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice
Philp D et al. · Wound Repair and Regeneration · cited by Peptides
In vitro · 2003
The effect of cyclical compressive loading on gene expression in articular cartilage
Blain EJ et al. · Biorheology · cited by Peptides
Animal · 2003 · n=20
Role of thymosin beta4 in tumor metastasis and angiogenesis
Cha HJ et al. · Journal of the National Cancer Institute · cited by Peptides
In vitro · 2002
The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants
Clark AG et al. · Matrix Biology · cited by Supplements
In vitro · 2002
HPLC and GC/MS determination of deuterated vitamin K (phylloquinone) in human serum after ingestion of deuterium-labeled broccoli
Dolnikowski GG et al. · The Journal of Nutritional Biochemistry · cited by Foods & Nutrition
In vitro · 2002
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis
Verzijl N et al. · Arthritis and Rheumatism · cited by Foods & Nutrition
In vitro · 2002
Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage
Chen AC et al. · Arthritis and Rheumatism · cited by Foods & Nutrition
In vitro · 2002
Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes
Ahmed S et al. · Free Radical Biology & Medicine · cited by Foods & Nutrition
RCT · 2002 · n=163
Structural effect of avocado/soybean unsaponifiables on joint space loss in osteoarthritis of the hip
Lequesne M et al. · Arthritis and Rheumatism · cited by Supplements
In vitro · 2002
The effect of thymosin beta4 on articular cartilage chondrocyte matrix metalloproteinase expression
Blain EJ et al. · Biochemical Society Transactions · cited by Peptides
Animal · 2002 · n=6
Plasma and synovial fluid concentrations of calcium pentosan polysulphate achieved in the horse following intramuscular injection
Fuller CJ et al. · Equine Veterinary Journal · cited by Peptides
Case report · 2002 · n=1
Massive bleeding on a bladder protectant: a case report of pentosan polysulfate sodium-induced coagulopathy
Gill S et al. · Archives of Internal Medicine · cited by Peptides
In vitro · 2002
Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage
Mastbergen SC et al. · Rheumatology (Oxford) · cited by Precautions
Animal · 2002
Synergistic effect of ofloxacin and magnesium deficiency on joint cartilage in immature rats
Lozo E et al. · Antimicrobial Agents and Chemotherapy · cited by Precautions
Cohort · 2002 · n=11
Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement
Vanwanseele B et al. · Arthritis and Rheumatism · cited by Exercise & Rehab and Precautions
RCT · 2002 · n=202
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study
Pavelká K et al. · Archives of Internal Medicine · cited by Supplements
In vitro · 2002
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4
Bhardwaj RK et al. · The Journal of Pharmacology and Experimental Therapeutics · cited by Supplements
Case series · 2002 · n=20
Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers
Volpi N · Osteoarthritis and Cartilage · cited by Foods & Nutrition and Supplements
RCT · 2002 · n=42
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects
Schwab U et al. · The American Journal of Clinical Nutrition · cited by Supplements
Case series · 2001 · n=15
A new recommended dietary allowance of vitamin C for healthy young women
Levine M et al. · Proceedings of the National Academy of Sciences · cited by Supplements
RCT · 2001 · n=261
Effects of a ginger extract on knee pain in patients with osteoarthritis
Altman RD et al. · Arthritis and Rheumatism · cited by Supplements
Animal · 2001
Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel
Li X et al. · Infection and Immunity · cited by Foods & Nutrition
In vitro · 2001
The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model
McCormack MC et al. · Archives of Facial Plastic Surgery · cited by Peptides
Review · 2001
Vascular mechanisms in osteoarthritis
Ghosh P et al. · Best Practice & Research. Clinical Rheumatology · cited by Peptides
Animal · 2001 · n=8
The effect of three different doses of sodium pentosan polysulphate on haematological and haemostatic variables in adult horses
Dart A et al. · Australian Veterinary Journal · cited by Peptides
In vitro · 2001
Biosynthetic response and mechanical properties of articular cartilage after injurious compression
Kurz B et al. · Journal of Orthopaedic Research · cited by Precautions
RCT · 2001 · n=212
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial
Reginster JY et al. · Lancet · cited by Supplements
Cohort · 2001 · n=22
Sulfate could mediate the therapeutic effect of glucosamine sulfate
Hoffer LJ et al. · Metabolism · cited by Foods & Nutrition and Supplements
Case series · 2001 · n=10
Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
Abdelmalek MF et al. · The American Journal of Gastroenterology · cited by Supplements
RCT · 2000 · n=394
A 5-year randomized controlled, double-blind study of glycosaminoglycan polysulphuric acid complex (Rumalon) as a structure modifying therapy in osteoarthritis of the hip and knee
Pavelká K et al. · Osteoarthritis and Cartilage · cited by Peptides
Case series · 2000 · n=31
Immunomodulatory properties of rumalon, a glycosaminoglycan peptide complex, in patients with osteoarthritis: activation of T helper cell type 2 cytokines and antigen-specific IgG4 antigen-specific igG4 antibodies
Klein R et al. · The Journal of Rheumatology · cited by Peptides
In vitro · 2000
Discrete reduction of type I collagen thermal stability upon oxidation
Komsa-Penkova R et al. · Biophysical Chemistry · cited by Foods & Nutrition and Supplements
In vitro · 2000
Effect of collagen turnover on the accumulation of advanced glycation end products
Verzijl N et al. · The Journal of Biological Chemistry · cited by Foods & Nutrition
RCT · 2000
A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis
Bliddal H et al. · Osteoarthritis and Cartilage · cited by Supplements
In vitro · 2000
n-3 fatty acids specifically modulate catabolic factors involved in articular cartilage degradation
Curtis CL et al. · The Journal of Biological Chemistry · cited by Foods & Nutrition
Animal · 2000
Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(2+)
Siméon A et al. · The Journal of Investigative Dermatology · cited by Peptides
In vitro · 2000
The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures
Siméon A et al. · Life Sciences · cited by Peptides
Animal · 2000
Efficacy of oral calcium pentosan polysulphate for the treatment of osteoarthritis of the canine stifle joint secondary to cranial cruciate ligament deficiency
Innes JF et al. · The Veterinary Record · cited by Peptides
In vitro · 2000
Production of tissue inhibitor of metalloproteinases 3 is selectively enhanced by calcium pentosan polysulfate in human rheumatoid synovial fibroblasts
Takizawa M et al. · Arthritis and Rheumatism · cited by Peptides
In vitro · 2000
Calcium pentosan polysulfate inhibits the catabolism of aggrecan in articular cartilage explant cultures
Munteanu SE et al. · Arthritis and Rheumatism · cited by Peptides
Animal · 2000
Incomplete restoration of immobilization induced softening of young beagle knee articular cartilage after 50-week remobilization
Haapala J et al. · International Journal of Sports Medicine · cited by Precautions
RCT · 2000 · n=241
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis
Shiraki M et al. · Journal of Bone and Mineral Research · cited by Supplements
Animal · 1999
Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL)
Oesser S et al. · The Journal of Nutrition · cited by Supplements
RCT · 1999
Response of vitamin K status to different intakes and sources of phylloquinone-rich foods: comparison of younger and older adults
Booth SL et al. · The American Journal of Clinical Nutrition · cited by Foods & Nutrition
Animal · 1999
Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
Siméon A et al. · The Journal of Investigative Dermatology · cited by Peptides
Animal · 1999
Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits
Sebecić B et al. · Bone · cited by Peptides
Review · 1999
The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment
Ghosh P · Seminars in Arthritis and Rheumatism · cited by Peptides
RCT · 1999 · n=18
The oral bioavailability of pentosan polysulphate sodium in healthy volunteers
Faaij RA et al. · European Journal of Clinical Pharmacology · cited by Peptides
In vitro · 1999
The effects of NSAID on the matrix of human articular cartilages
Dingle JT · Zeitschrift für Rheumatologie · cited by Precautions
RCT · 1999 · n=190
Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis
McKown KM et al. · Arthritis and Rheumatism · cited by Supplements
RCT · 1998
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
Shoba G et al. · Planta Medica · cited by Supplements
RCT · 1998 · n=274
Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial
Barnett ML et al. · Arthritis and Rheumatism · cited by Supplements
Animal · 1997
Dose-dependent protective effect of BPC 157 on capsaicin-induced rhinitis in rats
Kalogjera L et al. · European Archives of Oto-Rhino-Laryngology · cited by Peptides
In vitro · 1997
[Use of Bioimplants to Replace Cartilage Part I: Chondrocyte Cultivation in Three-dimensional Gel.]
Pesáková V et al. · Acta Chirurgiae Orthopaedicae et Traumatologiae Čechoslovaca · cited by Peptides
Animal · 1997
[Use of Bioimplants to Replace Cartilage Part II: Application of Implants in Animal Experiments.]
Adam M et al. · Acta Chirurgiae Orthopaedicae et Traumatologiae Čechoslovaca · cited by Peptides
Animal · 1997
Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and adjuvant arthritis in rats
Sikiric P et al. · Journal of Physiology, Paris · cited by Peptides
Meta-analysis · 1997 · n=398
Efficacy of pentosan polysulfate in the treatment of interstitial cystitis: a meta-analysis
Hwang P et al. · Urology · cited by Peptides
Animal · 1997
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
Luo G et al. · Nature · cited by Supplements
Cohort · 1997 · n=31,516
Cartilage injuries: a review of 31,516 knee arthroscopies
Curl WW et al. · Arthroscopy · cited by 1 page
Cohort · 1996 · n=640
Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis?
McAlindon TE et al. · Arthritis and Rheumatism · cited by Supplements
Case series · 1996 · n=7
Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
Levine M et al. · Proceedings of the National Academy of Sciences · cited by Supplements
Animal · 1996
Morphological features of bone healing under the effect of collagen-graft-glycosaminoglycan copolymer supplemented with the tripeptide Gly-His-Lys
Pohunková H et al. · Biomaterials · cited by Peptides
Animal · 1996 · n=12
Effect of locally injected medications on healing of pad wounds in dogs
Swaim SF et al. · American Journal of Veterinary Research · cited by Peptides
Animal · 1996 · n=40
Systemic use of pentosan polysulphate in the treatment of osteoarthritis
Read RA et al. · The Journal of Small Animal Practice · cited by Peptides
Case report · 1996 · n=1
Pentosan polysulfate-induced thrombocytopenia: a case diagnosed with an ELISA test used for heparin-induced thrombocytopenia
Gironell A et al. · Annals of Hematology · cited by Peptides
RCT · 1996 · n=90
Oral type II collagen treatment in early rheumatoid arthritis. A double-blind, placebo-controlled, randomized trial
Sieper J et al. · Arthritis and Rheumatism · cited by Supplements
Animal · 1995
BPC-15 reduces trinitrobenzene sulfonic acid-induced colonic damage in rats
Veljaca M et al. · Journal of Pharmacology and Experimental Therapeutics · cited by Peptides
In vitro · 1995
The kinetics of the thermal denaturation of collagen in unrestrained rat tail tendon determined by differential scanning calorimetry
Miles CA et al. · Journal of Molecular Biology · cited by Foods & Nutrition
In vitro · 1995
Effect of the tripeptide glycyl-L-histidyl-L-lysine on the proliferation and synthetic activity of chick embryo chondrocytes
Pesáková V et al. · Biomaterials · cited by Peptides
In vitro · 1995
Effects of the tripeptide glycyl-L-histidyl-L-lysine copper complex on osteoblastic cell spreading, attachment and phenotype
Godet D et al. · Cellular and Molecular Biology · cited by Peptides
Animal · 1995
Effect of tripeptide-copper complexes on the process of skin wound healing and on cultured fibroblasts
Buffoni F et al. · Archives Internationales de Pharmacodynamie et de Thérapie · cited by Peptides
RCT · 1995 · n=812
Effects of antiinflammatory drugs on the progression of osteoarthritis of the knee. LINK Study Group. Longitudinal Investigation of Nonsteroidal Antiinflammatory Drugs in Knee Osteoarthritis
Huskisson EC et al. · Journal of Rheumatology · cited by Precautions
In vitro · 1994
SPARC is a source of copper-binding peptides that stimulate angiogenesis
Lane TF et al. · The Journal of Cell Biology · cited by Peptides
RCT · 1994 · n=39
Effects of local heat and cold treatment on surface and articular temperature of arthritic knees
Oosterveld FG et al. · Arthritis and Rheumatism · cited by Light, Heat & Devices
Case series · 1994 · n=23
Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
Brittberg M et al. · The New England Journal of Medicine · cited by Treatments & Surgery
In vitro · 1993
Kinetics of collagen denaturation in mammalian lens capsules studied by differential scanning calorimetry
Miles CA · International Journal of Biological Macromolecules · cited by Foods & Nutrition
Animal · 1993
In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds
Maquart FX et al. · The Journal of Clinical Investigation · cited by Peptides
RCT · 1993 · n=148
A quantitatively controlled method to study prospectively interstitial cystitis and demonstrate the efficacy of pentosanpolysulfate
Parsons CL et al. · The Journal of Urology · cited by Peptides
Animal · 1993
Pentosan polysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo
Francis DJ et al. · Rheumatology International · cited by Peptides
Animal · 1993
Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate
Rogachefsky RA et al. · Osteoarthritis and Cartilage · cited by Peptides
RCT · 1993 · n=60
Effects of oral administration of type II collagen on rheumatoid arthritis
Trentham DE et al. · Science · cited by Supplements
In vitro · 1993
Thymosin beta-4 expression is correlated with metastatic capacity of colorectal carcinomas
Yamamoto T et al. · Biochemical and Biophysical Research Communications · cited by Peptides
RCT · 1992 · n=86
A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers
Bishop JB et al. · Journal of Vascular Surgery · cited by Peptides
In vitro · 1992
Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
Wegrowski Y et al. · Life Sciences · cited by Peptides
In vitro · 1992
Thymosin beta 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes
Cassimeris L et al. · The Journal of Cell Biology · cited by Peptides
Review · 1991
Agricultural practices affect arthritis
Newnham RE · Nutrition and Health · cited by Foods & Nutrition
In vitro · 1990
Effects of glycyl-histidyl-lysyl chelated Cu(II) on ferritin dependent lipid peroxidation
Miller DM et al. · Advances in Experimental Medicine and Biology · cited by Peptides
RCT · 1990 · n=110
Pentosan polysulfate sodium for therapy of interstitial cystitis. A double-blind placebo-controlled clinical study
Mulholland SG et al. · Urology · cited by Peptides
Animal · 1989
Pentosan polysulfate (Cartrophen) prevents the hydrocortisone induced loss of hyaluronic acid and proteoglycans from cartilage of rabbit joints as well as normalizes the keratan sulfate levels in their serum
Kongtawelert P et al. · The Journal of Rheumatology · cited by Peptides
RCT · 1989 · n=105
Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis
Rashad S et al. · Lancet · cited by Precautions
Case series · 1989
Iron, copper, and zinc status: response to supplementation with zinc or zinc and iron in adult females
Yadrick MK et al. · The American Journal of Clinical Nutrition · cited by Supplements
Review · 1988
The sauna and rheumatic diseases
Isomäki H · Annals of Clinical Research · cited by Light, Heat & Devices
In vitro · 1988
Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
Maquart FX et al. · FEBS Letters · cited by Peptides
RCT · 1987 · n=115
A prospective double-blind clinically controlled multicenter trial of sodium pentosanpolysulfate in the treatment of interstitial cystitis and related painful bladder disease
Holm-Bentzen M et al. · The Journal of Urology · cited by Peptides
RCT · 1987 · n=15
Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans
Barrie SA et al. · Agents and Actions · cited by Supplements
Animal · 1986
Softening of canine articular cartilage after immobilization of the knee joint
Jurvelin J et al. · Clinical Orthopaedics and Related Research · cited by Precautions
Animal · 1986
Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen
Nagler-Anderson C et al. · Proceedings of the National Academy of Sciences of the United States of America · cited by Supplements
Animal · 1982
Aspirin aggravates the degeneration of canine joint cartilage caused by immobilization
Palmoski MJ et al. · Arthritis and Rheumatism · cited by Precautions
RCT · 1982 · n=27
Zinc sulphate in rheumatoid arthritis
Mattingly PC et al. · Annals of the Rheumatic Diseases · cited by Supplements
Case series · 1982 · n=22
Lack of beneficial effect of zinc sulphate in rheumatoid arthritis
Rasker JJ et al. · Scandinavian Journal of Rheumatology · cited by Supplements
In vitro · 1981
Natural occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains, and beverages
Pearson TW et al. · Journal of Agricultural and Food Chemistry · cited by Foods & Nutrition and Supplements
In vitro · 1980
Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells
Pickart L et al. · Nature · cited by Peptides
Cohort · 1979 · n=186
Indomethacin treatment in osteoarthritis of the hip joint. Does the treatment interfere with the natural course of the disease?
Rønningen H et al. · Acta Orthopaedica Scandinavica · cited by Precautions
In vitro · 1977
Growth-modulating serum tripeptide is glycyl-histidyl-lysine
Schlesinger DH et al. · Experientia · cited by Peptides
RCT · 1976 · n=24
Oral zinc sulphate in rheumatoid arthritis
Simkin PA · Lancet · cited by Supplements
In vitro · 1966
Dimethyl sulfone: isolation from cows' milk
Williams KI et al. · Proceedings of the Society for Experimental Biology and Medicine · cited by Foods & Nutrition and Supplements
Case series · 1961
The etiology of chondromalacia patellae
Outerbridge RE · The Journal of Bone and Joint Surgery. British Volume · cited by 1 page