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RCT · 2023 · n=39

The Effect of Specific Bioactive Collagen Peptides on Tendon Remodeling during 15 wk of Lower Body Resistance Training

Balshaw TG, Funnell MP, McDermott EJ, Maden-Wilkinson TM, Massey GJ, James LJ, Folland JP · Medicine and Science in Sports and Exercise

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Comprehensively null, with MRI as the outcome measure. Verbatim: 'No between-group differences were detected for any of the tendinous tissue adaptations to RT (ANOVA group-time, 0.365 <= P <= 0.877).' Both groups improved identically, and placebo was numerically higher on every mechanical measure — patellar tendon stiffness +17.3% on collagen vs +20.9% on placebo, Young's modulus +17.8% vs +20.6%.

Population
Young healthy recreationally active men undertaking 15 weeks of standardized lower-body resistance training 3x weekly
Intervention
15 g specific bioactive collagen peptides daily
Comparator
Placebo
Limitations
Healthy young men with no tendon pathology, so it tests augmentation of normal training adaptation rather than treatment of an injured tendon. Tendon rather than cartilage. Independent (Loughborough).

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