Bone Marrow Aspirate Concentrate Is Equivalent to Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis at 2 Years: A Prospective Randomized Trial

Anz AW, Plummer HA, Cohen A, et al. · The American Journal of Sports Medicine

Both groups improved significantly and remained improved at 24 months with no difference between BMAC and PRP at any time point — BMAC's extra cost and morbidity bought nothing over PRP.

Population

Adults with symptomatic knee OA (KL 1-3)

Intervention

Single BMAC injection

Comparator

Single leukocyte-rich PRP injection

Limitations

No placebo arm; patient-reported outcomes only.