An accelerated 6-week return to full weight bearing after matrix-induced autologous chondrocyte implantation results in good clinical outcomes to 5 years post-surgery

Ebert JR, Edwards P, Janes GC, et al. · Knee Surgery, Sports Traumatology, Arthroscopy

No differences between rehab arms to a minimum 5 years; both improved significantly with 8.1% graft failure overall — faster loading did not harm the graft.

Population

35 patients (37 knees) after MACI to femoral condyle/trochlea, randomized to 6- vs 8-week return to full weight bearing

Intervention

Accelerated rehabilitation (full weight bearing at 6 weeks)

Comparator

Conservative rehabilitation (full weight bearing at 8 weeks)

Limitations

Small RCT powered for rehab timing, not efficacy; single group of surgeons.