GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

Pickart L, Vasquez-Soltero JM, Margolina A · BioMed Research International

Summarizes wound-healing and cosmetic-dermatology evidence and broad gene-modulation claims, and estimates 100–200 mg as a therapeutic human dose from animal systemic-healing work with no human dose-finding; contains no joint, tendon, or cartilage clinical data.

Population

Narrative review of GHK/GHK-Cu skin and gene-expression literature

Intervention

n/a

Comparator

n/a

Limitations

All three authors work at Skin Biology, the lead author's company selling GHK-Cu products, while the paper declares no conflict of interests; the ~4,000-gene claim comes from Broad Institute Connectivity Map expression screens, not from outcomes.