Association between Dietary Magnesium Intake and Radiographic Knee Osteoarthritis

Zeng C, Li H, Wei J, Yang T, Deng ZH, Yang Y, Zhang Y, Yang TB, Lei GH · PLoS One

Replicates the inverse association between dietary magnesium and radiographic knee osteoarthritis in a different population and diet: against the lowest quintile, the odds of radiographic knee OA were 0.53 (95% CI 0.28-1.01) in the third quintile and 0.40 (0.17-0.94) in the fourth, with joint-space narrowing following and osteophytes not.

Population

A Chinese population-based sample with knee radiographs scored by the OARSI atlas

Intervention

Higher dietary magnesium intake

Comparator

Lower intake

Limitations

Cross-sectional, self-reported intake, and the same confounding with overall dietary quality. Prevalent rather than incident disease. Radiographs read by two orthopaedists blinded to symptoms; funded by Hunan provincial, university and National Natural Science Foundation of China grants.