Betaine Supplementation Does Not Improve Muscle Hypertrophy or Strength Following 6 Weeks of Cross-Fit Training

Moro T, Badiali F, Fabbri I, Paoli A · Nutrients

Back-squat strength rose within the betaine group (P=0.04) but not within placebo, and the between-group difference was not significant; body composition, cell hydration, rowing performance and anaerobic capacity did not differ.

Population

Trained CrossFit athletes matched for training status and body fat, 6 weeks

Intervention

Betaine supplementation during 6 weeks of CrossFit training

Comparator

Placebo plus identical training

Limitations

29 already-trained participants for 6 weeks; the headline within-group improvement is the weaker comparison, and the between-group test was null.