Limited effects of non-steroidal anti-inflammatory drugs (NSAIDs) on imaging outcomes in osteoarthritis: observational data from the osteoarthritis initiative (OAI)

Kreutzinger V, et al. · BMC Musculoskeletal Disorders

NSAID use showed limited association with MRI structural progression overall; cartilage-lesion progression was, if anything, slightly slower in some NSAID-user subgroups.

Population

Osteoarthritis Initiative participants with serial knee MRI

Intervention

Regular NSAID use (observed)

Comparator

Non-users

Limitations

Observational; heterogeneous NSAID types and doses pooled.