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RCT · 2023 · n=50

Specific collagen peptides increase adaptions of patellar tendon morphology following 14-weeks of high-load resistance training: A randomized-controlled trial

Jerger S, Centner C, Lauber B, Seynnes O, Friedrich T, Lolli D, Gollhofer A, König D · European Journal of Sport Science

Promisingcounts toward this tier

Patellar tendon cross-sectional area increased more on collagen than placebo at 60% and 70% of tendon length from the proximal insertion. The rest of the trial was null: tendon stiffness, muscle cross-sectional area and maximal strength all rose, equally, in both groups. Same signature as the Achilles trial from the same group — the tendon got bigger without measurably performing better.

Population
Healthy, moderately active men completing 14 weeks of knee-extensor resistance training at 70-85% of one-rep max
Intervention
5 g specific collagen peptides daily
Comparator
5 g placebo, same training
Limitations
Healthy young men with no tendon pathology, so this tests augmentation of a normal training adaptation. Regional cross-sectional area is a positive result at two of several measurement sites. Registered as DRKS00029244. Directly contradicted on both size and stiffness by the independent 15-week MRI trial (pmid-37436929).

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