Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study

Veronese N, Koyanagi A, Stubbs B, et al. · Clinical Nutrition

Highest versus lowest Mediterranean-diet adherence was associated with a 9% lower risk of incident symptomatic knee OA (RR 0.91, 95% CI 0.82-0.998) and marginally less pain worsening (RR 0.96) over 4 years — statistically fragile margins in both cases.

Population

Adults with or at risk of knee OA (Osteoarthritis Initiative), 4-year follow-up

Intervention

Adherence to Mediterranean diet (aMED quintiles, observational)

Limitations

Observational; confidence intervals barely exclude 1; residual confounding by weight, activity, and socioeconomic status plausible.