A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis

Kumar S, Sugihara F, Suzuki K, Inoue N, Venkateswarathirukumara S · Journal of the Science of Food and Agriculture

Both the porcine and the bovine peptide arms reduced WOMAC and VAS scores and improved quality of life, while the placebo arm's endpoint indices were unchanged. Two source materials tested against one placebo in a single trial, which is rare in this literature.

Population

Adults with osteoarthritis, 13 weeks

Intervention

Porcine and bovine collagen peptide, separate arms

Comparator

Placebo

Limitations

Group sizes and doses are not stated in the abstract, and no funding statement was available in the indexed record. Thirteen weeks, symptom scores only. Reporting each arm as improved against its own baseline while placebo did not is a weaker claim than a between-group comparison.