Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat

Cerovecki T, Bojanic I, Brcic L, et al. · Journal of Orthopaedic Research

Functional, biomechanical, macroscopic, and histological improvement of MCL healing across intraperitoneal, oral, and topical routes.

Population

Rats with transected medial collateral ligament

Intervention

BPC 157 10 µg or 10 ng/kg i.p., 0.16 µg/mL in drinking water, or 1 µg topical; up to 90 days

Comparator

Saline

Limitations

Zagreb-affiliated group; no blinded independent replication; species gap to human ligament.