Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides

Ashapkin V, Khavinson V, Shilovsky G, et al. · Molecular Biology Reports

AED increased IGF1 expression several-fold and shifted aging-related gene expression in MSCs — gene-expression changes only, no functional cartilage endpoint.

Population

Aging human mesenchymal stem cell cultures

Intervention

Tripeptides AED (Cartalax), KED, and dipeptide KE

Comparator

Untreated cultures

Limitations

Khavinson is a co-author; expression-level outcomes; no tissue or organism-level confirmation.