Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study

Sengupta K, Krishnaraju AV, Vishal AA, et al. · International Journal of Medical Sciences

Both extracts improved pain and function scores versus placebo by day 90 (improvements beginning around day 7), with Aflapin numerically superior to 5-Loxin.

Population

Adults with knee osteoarthritis, India

Intervention

5-Loxin 100 mg/day or Aflapin 100 mg/day (Boswellia extracts) for 90 days

Comparator

Placebo

Limitations

Manufacturer-run trial (Laila Nutraceuticals authors); small arms (~20/group); same research group as the prior 5-Loxin trial.