Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

Rahman OF, Lee SJ, Seeds WA · JAAOS Global Research and Reviews

Groups GHK-Cu with the wound-healing peptides acting through angiogenesis, integrin-mediated extracellular-matrix remodelling and fibroblast activation, and states plainly that preclinical work is promising while clinical trials are absent.

Population

Narrative review of therapeutic peptides in orthopaedic practice

Intervention

n/a

Comparator

n/a

Limitations

Narrative review; mechanistic framing is drawn from the dermal and pulmonary literature rather than from orthopaedic data.