Consumption of 100% Tart Cherry Juice Reduces Serum Urate in Overweight and Obese Adults

Martin KR, Coles KM · Current Developments in Nutrition

Serum urate fell 19.2% on tart cherry juice (p < 0.05). hsCRP fell 19.4% and MCP-1 6.3%, neither reaching significance (p = 0.09 and p = 0.08). Lipids, glycaemia and insulin resistance did not move.

Population

Overweight and obese adults (BMI > 25), 18 women and 8 men, the 26 completers of 34 enrolled; 46% were hyperuricaemic at baseline

Intervention

240 mL/day of 100% tart cherry juice for 4 weeks

Comparator

Placebo beverage, crossover with a 4-week washout

Limitations

n=26, overweight but otherwise healthy rather than diseased, 4 weeks, and the inflammatory markers missed significance. The juice concentrate and the placebo formulation came from the Cherry Marketing Institute, which funded the trial and had no further role. Registered NCT03636529.