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In vitro · 2019
Preclinicalcounts toward this tierHydroxytyrosol promotes autophagy by regulating SIRT1 against advanced oxidation protein product-induced NADPH oxidase and inflammatory response
Sun T, Chen Q, Zhu SY, Wu Q, Liao CR, Wang Z, Wu XH, Wu HT, Chen JT · International Journal of Molecular Medicine
Preclinicalcounts toward this tier
Restores autophagy through SIRT1 and blunts NADPH-oxidase-driven inflammation — the autophagy arm of the olive-polyphenol case, which is what distinguishes it from a plain antioxidant story.
- Population
- Cells exposed to advanced oxidation protein products
- Intervention
- Hydroxytyrosol
- Comparator
- Untreated
- Limitations
- Cell culture; the stressor is a chemical oxidation product rather than a joint condition.
Cited by
1 entry references this study
- Olive oilPRECL.
Foods & Nutrition → Foods with joint trials