Improved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment

Sampson MJ, Kabbani M, Krishnan R, et al. · BMC Musculoskeletal Disorders

MRI resolution of bone marrow edema with pain falling from 8/10 to 0 — hypothesis-generating only.

Population

70-year-old woman with knee OA and bone marrow edema lesion

Intervention

PPS IM twice weekly for 3 weeks

Comparator

None

Limitations

Single patient; drug supplied by Paradigm Biopharmaceuticals and an author was a company employee.