The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration

Chang CH, Tsai WC, Lin MS, et al. · Journal of Applied Physiology

Accelerated tendon fibroblast outgrowth, improved survival under oxidative stress, and dose-dependent increases in migration via FAK-paxillin signaling.

Population

Rat Achilles tendon explants and cultured tendon fibroblasts

Intervention

BPC 157 at graded concentrations in culture

Comparator

Untreated cultures

Limitations

Cell/explant work only; one of the few positive results from outside the Zagreb group, but still preclinical.