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In vitro · 2003
Preclinicalcounts toward this tierEpithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Khavinson VKh, Bondarev IE, Butyugov AA · Bulletin of Experimental Biology and Medicine
Preclinicalcounts toward this tier
Reports induction of telomerase activity and telomere elongation in somatic cells — the single most-cited claim of the whole program, and the origin of the telomerase language used in bioregulator marketing.
- Population
- Human fetal fibroblast cultures
- Intervention
- Epithalon (AEDG)
- Comparator
- Untreated cultures
- Limitations
- Two-page report from the originating institute; a different peptide from Cartalax. The first reproduction by a laboratory with no institute author came in 2025, twenty-two years later, in two normal human cell lines, alongside a finding the original did not test: telomere lengthening in cancer lines through the ALT pathway.
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