Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation

Krivic A, Anic T, Seiwerth S, et al. · Journal of Orthopaedic Research

Improved tendon-to-bone healing on functional and biomechanical measures and counteracted corticosteroid-impaired healing.

Population

Rats with Achilles tendon detached from the calcaneus

Intervention

BPC 157 10 µg, 10 ng, or 10 pg/kg i.p. daily for up to 21 days

Comparator

Saline; 6α-methylprednisolone arm

Limitations

Same core lab as most BPC-157 work; rodent model only.