Review · 2018
Promisingcounts toward this tierWhat is the evidence for a role for diet and nutrition in osteoarthritis?
Thomas S, Browne H, Mobasheri A, Rayman MP · Rheumatology (Oxford)
A clinical overview of diet and nutrition in osteoarthritis, and it orders the options: weight reduction with exercise first and by a distance; then dietary lipid modification, with long-chain omega-3s from oily fish or supplements, justified partly through the metabolic-syndrome link to OA; then adequate micronutrient intake, singling out vitamin K for its role in bone and cartilage mineralization. It judges the evidence for vitamin D supplementation in OA unconvincing, and notes a strong association between OA and raised serum cholesterol.
- Population
- The diet-and-osteoarthritis literature, reviewed for clinicians
- Intervention
- Dietary modification across weight, lipids, omega-3s and micronutrients
- Comparator
- Not applicable
- Limitations
- A narrative clinical review rather than a systematic one, with no pooling or formal quality appraisal; the authors declare no conflicts.
Cited by
4 entries reference this study
- Body weight & the kneeSTRONG
Foods & Nutrition → Load & body weight
Evidence for that entry
Strong - Oily fishPRECL.
Foods & Nutrition → Foods with joint trials
Evidence for that entry
Preclinical - Omega-3s & fish oilPRECL.
Foods & Nutrition → Nutrients & minerals from food
Evidence for that entry
Preclinical - The anti-inflammatory dietPROM.
Foods & Nutrition → Dietary patterns
Evidence for that entry
Promising