Chondrocytes secretory phenotype associated with aging: role in the pathogenesis of osteoarthritis and prospects for peptide bioregulation

Myakisheva SN, Linkova NS, Kozhevnikova EO, et al. · Advances in Gerontology (Uspekhi Gerontologii)

Asserts efficacy of Sigumir and the AED tripeptide (Cartalax) in OA animal models and elderly patients, but cites institute-affiliated primary sources rather than independent trials.

Population

Narrative review of chondrocyte aging and Khavinson peptide claims

Intervention

n/a

Comparator

n/a

Limitations

Authors from the originating institute reviewing their own program; primary human data behind the claims are not independently indexed.