An Investigation into the Effects of a Curcumin Extract (Curcugen) on Osteoarthritis Pain of the Knee: A Randomised, Double-Blind, Placebo-Controlled Study

Lopresti AL, Smith SJ, Jackson-Michel S, Fairchild T · Nutrients

KOOS knee pain (p=0.009) and numeric pain ratings (p=0.001) improved versus placebo, along with the timed up-and-go, 6-minute walk and JOA score; the 30-second chair stand and 40 m fast-paced walk did not separate. Pain medication was reduced in 37% on curcumin versus 13% on placebo.

Population

Adults with knee osteoarthritis, Australia

Intervention

Curcugen standardised curcumin extract 500 mg twice daily for 8 weeks

Comparator

Placebo

Limitations

8 weeks; supported by the extract supplier (Gencor), and two of four performance tests did not separate from placebo.