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Meta-analysis · 2016 · n=606

Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Daily JW, Yang M, Park S · Journal of Medicinal Food

Promisingcounts toward this tier

About 1000 mg/day of curcumin reduced arthritis pain and improved function versus placebo, with effects comparable to NSAIDs in head-to-head trials; the authors nonetheless judged the trial base too small and short to be definitive.

Population
8 randomized trials of turmeric/curcumin in arthritis (mostly knee OA)
Intervention
Turmeric extracts or curcumin, typically ~1000 mg/day for 8-12 weeks
Comparator
Placebo or active comparator (NSAIDs)
Limitations
Few, small, short trials with heterogeneous formulations; authors explicitly call the evidence insufficient for firm conclusions.

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