Microfragmented Adipose Tissue Injection Reduced Pain Compared With a Saline Control Among Patients With Symptomatic Osteoarthritis of the Knee During 1-Year Follow-Up: A Randomized Controlled Trial

Richter DL, et al. · Arthroscopy

MFAT showed statistically significant improvements over saline across primary pain/function outcomes at 1 year; corticosteroid benefit was significant only at 2-6 weeks.

Population

75 adults with symptomatic knee OA

Intervention

Single microfragmented adipose tissue (MFAT) injection

Comparator

Corticosteroid or saline injection

Limitations

Partially blinded; lead author reports equipment/supplies from Lipogems (MFAT device maker); modest n per arm.