Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions in Mild to Moderate Osteoarthritic Knees: Results of a 2-Year Multicenter Prospective Study

Kon E, Di Matteo B, Verdonk P, et al. · The American Journal of Sports Medicine

All KOOS subscales improved significantly at 24 months (pain 49.6 to 79.5); MRI showed 78.7% defect surface coverage; 9.3% treatment failure needing revision — the study extending the indication toward OA knees.

Population

86 patients with joint surface lesions in knees with mild-to-moderate osteoarthritis (Kellgren-Lawrence 2-3), multicenter

Intervention

Agili-C aragonite scaffold

Comparator

None

Limitations

Uncontrolled industry-sponsored cohort; 2-year horizon; OA progression beyond that unknown.