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Meta-analysis · 2025 · n=5,162

Conversion to Total Knee Arthroplasty After High Tibial Osteotomy: A Systematic Review and Meta-analysis

Loke RWK, et al. · Orthopaedic Journal of Sports Medicine

Promisingcounts toward this tier

Conversion to total knee replacement: 4.5% before 5 years, 8.3% at 5-10 years, 11.2% beyond 10 years; overall complications 12.1%. Adding cartilage repair procedures showed no significant survival benefit in pooled data.

Population
5,162 HTO patients across 59 studies
Intervention
High tibial osteotomy
Comparator
None (pooled conversion rates)
Limitations
Declares itself 'Systematic review; Level of evidence, 4'. Heterogeneous techniques and eras pooled, and the concomitant-cartilage arm mixes stem-cell augmentation, osteochondral allograft, microfracture, abrasion arthroplasty and ACI as one category. The null for concomitant cartilage repair conflicts with smaller controlled series.

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1 entry references this study