Analysis of correlation between the consumption of beverages and the risk of radiographic knee osteoarthritis in Korean people: A cross-sectional study using the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V-1, 2)

Lim CO, Park HJ, Koo BM, Kim BT, Kim JG, Choi GW · Medicine (Baltimore)

Soft drinks, green tea and milk showed no significant relationship with radiographic knee OA in either sex. The only association was coffee, inversely, in women only (p < 0.05, p for trend < 0.05) — which points the opposite way from the Mendelian randomization literature on coffee.

Population

5,503 adults in the Fifth Korea National Health and Nutrition Examination Survey with knee radiographs

Intervention

Frequency of drinking coffee, green tea, milk or soft drinks

Comparator

Non-drinkers of each

Limitations

Cross-sectional national survey data, beverage frequency by questionnaire, prevalent radiographic disease. A single-sex association among eight tested beverage-sex combinations is what multiple comparisons produce.