The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses

Bideshki MV, Jourabchi-Ghadim N, Radkhah N, Behzadi M, Asemani S, Jamilian P, Zarezadeh M · Phytotherapy Research

The umbrella analysis found consistent pooled reductions in VAS, total WOMAC and the WOMAC pain, function and stiffness subscales, and concluded the evidence supports curcuminoid supplementation for symptom relief.

Population

11 meta-analyses of RCTs of curcumin supplementation in osteoarthritis

Intervention

Curcumin supplementation

Comparator

Placebo or control

Limitations

Umbrella reviews inherit rather than repair the underlying trials, and the 11 meta-analyses overlap heavily on the same small studies, so the apparent consistency is partly the same data counted repeatedly.