Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth

Staresinic M, Sebecic B, Patrlj L, et al. · Journal of Orthopaedic Research

Treated tendons showed higher load to failure, better functional (Achilles functional index) scores, and improved collagen organization than saline controls.

Population

Rats with surgically transected Achilles tendon

Intervention

BPC 157 10 µg, 10 ng, or 10 pg/kg i.p. daily for up to 14 days

Comparator

Saline

Limitations

Single research network (Zagreb group); rodent model; no independent replication in humans.