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RCT · 2022 · n=40

Effects of specific collagen peptide supplementation combined with resistance training on Achilles tendon properties

Jerger S, Centner C, Lauber B, Seynnes O, Sohnius T, Jendricke P, Oesser S, Gollhofer A, König D · Scandinavian Journal of Medicine & Science in Sports

Promisingcounts toward this tier

The strongest positive tendon result: Achilles tendon cross-sectional area rose 11.0% on collagen against 4.7% on placebo (p=0.002), with greater plantar flexor muscle thickness too (p=0.014). Read the omission though — tendon STIFFNESS and muscle strength increased in both groups with no significant difference, so the tissue got bigger without measurably performing better.

Population
Healthy male volunteers, mean age 26, completing a 14-week high-load resistance training programme
Intervention
5 g specific collagen peptides daily
Comparator
5 g placebo, same training
Limitations
Healthy young men, so it tests augmentation of normal training adaptation rather than repair. Co-author Oesser is at the Collagen Research Institute, the GELITA-linked arm. Directly contradicted on mechanical outcomes by the independent 15-week MRI trial (pmid-37436929), which found nothing on either size or stiffness.

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1 entry references this study