Creatine monohydrate supplementation does not improve functional recovery after total knee arthroplasty

Roy BD, de Beer J, Harvey D, Tarnopolsky MA · Archives of Physical Medicine and Rehabilitation

NULL: creatine produced no significant benefit for body composition, muscle strength, or functional recovery after knee replacement.

Population

Adults with OA undergoing total knee arthroplasty (17 men, 20 women)

Intervention

Creatine 10 g/day for 10 days pre-surgery, then 5 g/day for 30 days post-surgery

Comparator

Placebo

Limitations

Small; peri-operative catabolic setting may swamp supplement effects; short supplementation window.