Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial

Kimmatkar N, Thawani V, Hingorani L, Khiyani R · Phytomedicine

All patients receiving boswellia reported decreased knee pain, increased knee flexion, and increased walking distance versus placebo; pain scores fell substantially during active treatment.

Population

Adults with knee osteoarthritis, India (crossover design)

Intervention

Boswellia serrata extract 333 mg three times daily for 8 weeks, then crossover

Comparator

Placebo

Limitations

Very small (n=30), single-centre, extract supplied by manufacturer (Pharmanza); radiographic findings unchanged.